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Aliases for MIR4535 Gene

Subcategory (RNA class) for MIR4535 Gene


Quality Score for this RNA gene is


Aliases for MIR4535 Gene

  • MicroRNA 4535 2 3 5
  • Hsa-Mir-4535 3

External Ids for MIR4535 Gene

Previous GeneCards Identifiers for MIR4535 Gene

  • GC22U900801
  • GC22P049177

Summaries for MIR4535 Gene

Entrez Gene Summary for MIR4535 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4535 Gene

MIR4535 (MicroRNA 4535) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4535 Gene

Genomics for MIR4535 Gene

Regulatory Elements for MIR4535 Gene

Enhancers for MIR4535 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22F048783 0.4 ENCODE 0.8 +2.9 2909 0.2 CTCF TEAD4 CTBP2 RAD21 MIR4535 GC22M048815
GH22F048794 0.8 FANTOM5 0.4 +14.1 14114 0.1 MIR4535 GC22M048815
GH22F048796 0.6 ENCODE 0.3 +16.5 16499 0.2 JUND CEBPA TEAD4 CEBPB CEBPG NR2F2 GC22M048815 MIR4535
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4535 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4535 Gene

48,780,295 bp from pter
48,780,353 bp from pter
59 bases
Plus strand

Genomic View for MIR4535 Gene

Genes around MIR4535 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4535 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4535 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4535 Gene

Proteins for MIR4535 Gene

Post-translational modifications for MIR4535 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4535 Gene

Domains & Families for MIR4535 Gene

Gene Families for MIR4535 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4535: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4535 Gene

Function for MIR4535 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4535 Gene

Localization for MIR4535 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4535 Gene

Pathways & Interactions for MIR4535 Gene

SuperPathways for MIR4535 Gene

No Data Available

Interacting Proteins for MIR4535 Gene

Gene Ontology (GO) - Biological Process for MIR4535 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4535 Gene

Transcripts for MIR4535 Gene

mRNA/cDNA for MIR4535 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4535 Gene

No ASD Table

Relevant External Links for MIR4535 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4535 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4535 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4535 Gene

Orthologs for MIR4535 Gene

Evolution for MIR4535 Gene

Gene Tree for MIR4535 (if available)
Gene Tree for MIR4535 (if available)

No data available for Orthologs for MIR4535 Gene

Paralogs for MIR4535 Gene

No data available for Paralogs for MIR4535 Gene

Variants for MIR4535 Gene

Sequence variations from dbSNP and Humsavar for MIR4535 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs112511608 -- 48,780,758(+) TCCCC(A/G)GTGAG downstream-variant-500B
rs112931772 -- 48,780,017(+) CTGCG(-/TTCTC)TTCTC upstream-variant-2KB
rs113294319 -- 48,778,594(+) GCAGC(C/T)GCAGA upstream-variant-2KB
rs11374004 -- 48,779,727(+) ATAGG(-/A)AAAAA upstream-variant-2KB
rs113766434 -- 48,779,041(+) GGAAC(C/T)TACAC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4535 Gene

Variant ID Type Subtype PubMed ID
dgv4589n100 CNV gain 25217958
nsv1062235 CNV gain 25217958
nsv1064218 CNV gain 25217958
nsv589163 CNV gain 21841781

Relevant External Links for MIR4535 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4535 Gene

Disorders for MIR4535 Gene

Relevant External Links for MIR4535

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4535 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4535 Gene

Publications for MIR4535 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4535 Gene

Sources for MIR4535 Gene

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