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Aliases for MIR4532 Gene

Subcategory (RNA class) for MIR4532 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4532 Gene

  • MicroRNA 4532 2 3 5
  • Hsa-Mir-4532 3
  • Mir-4532 3

External Ids for MIR4532 Gene

Previous GeneCards Identifiers for MIR4532 Gene

  • GC20U900695
  • GC20P056472

Summaries for MIR4532 Gene

Entrez Gene Summary for MIR4532 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4532 Gene

MIR4532 (MicroRNA 4532) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4532 Gene

Genomics for MIR4532 Gene

Regulatory Elements for MIR4532 Gene

Enhancers for MIR4532 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH20F057918 0.2 ENCODE 0.3 +23.6 23606 1.9 MYC MIR4532 LOC100129869
GH20F057879 0.5 ENCODE 0.3 -15.2 -15150 1.6 MTA2 JUNB TBX21 MAFK ZBP1 MIR4532 LOC105372692
GH20F057927 0.5 ENCODE 0.3 +32.9 32859 1.5 HDGF SIX4 PKNOX1 NFXL1 YBX1 ZNF644 ZKSCAN1 ZFHX2 MTA3 CTBP1 RAB22A LOC100129869 MIR4532
GH20F057856 0.6 ENCODE 0.3 -38.5 -38515 0.2 CUX1 MIR4532 LOC105372692
GH20F057936 0.2 ENCODE 0.2 +41.7 41666 0.2 ZNF146 LOC100129869 MIR4532
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4532 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4532 Gene

Chromosome:
20
Start:
57,895,394 bp from pter
End:
57,895,444 bp from pter
Size:
51 bases
Orientation:
Plus strand

Genomic View for MIR4532 Gene

Genes around MIR4532 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4532 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4532 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4532 Gene

Proteins for MIR4532 Gene

Post-translational modifications for MIR4532 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4532 Gene

Domains & Families for MIR4532 Gene

Gene Families for MIR4532 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4532: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4532 Gene

Function for MIR4532 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4532 Gene

Localization for MIR4532 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4532 Gene

Pathways & Interactions for MIR4532 Gene

SuperPathways for MIR4532 Gene

No Data Available

Interacting Proteins for MIR4532 Gene

Gene Ontology (GO) - Biological Process for MIR4532 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4532 Gene

Transcripts for MIR4532 Gene

mRNA/cDNA for MIR4532 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4532 Gene

No ASD Table

Relevant External Links for MIR4532 Gene

GeneLoc Exon Structure for
MIR4532
ECgene alternative splicing isoforms for
MIR4532

Expression for MIR4532 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4532 Gene:

MIR4532
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4532 Gene

Orthologs for MIR4532 Gene

Evolution for MIR4532 Gene

ENSEMBL:
Gene Tree for MIR4532 (if available)
TreeFam:
Gene Tree for MIR4532 (if available)

No data available for Orthologs for MIR4532 Gene

Paralogs for MIR4532 Gene

No data available for Paralogs for MIR4532 Gene

Variants for MIR4532 Gene

Sequence variations from dbSNP and Humsavar for MIR4532 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs111968869 -- 57,893,927(+) CCTTC(C/T)GAGGA upstream-variant-2KB
rs112844463 -- 57,894,851(+) GAAGG(-/A)AAGGA upstream-variant-2KB
rs113328034 -- 57,894,740(+) GAAGG(A/G)GGAAG upstream-variant-2KB
rs113808830 -- 57,895,400(+) CAGAC(C/T)CCGGG nc-transcript-variant
rs113915545 -- 57,893,569(+) TTTCC(A/C)GCTGC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4532 Gene

Variant ID Type Subtype PubMed ID
esv2758802 CNV loss 17122850

Relevant External Links for MIR4532 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4532

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4532 Gene

Disorders for MIR4532 Gene

Relevant External Links for MIR4532

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4532

No disorders were found for MIR4532 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4532 Gene

Publications for MIR4532 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4532 Gene

Sources for MIR4532 Gene

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