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Aliases for MIR4531 Gene

Subcategory (RNA class) for MIR4531 Gene


Quality Score for this RNA gene is


Aliases for MIR4531 Gene

  • MicroRNA 4531 2 3 5
  • Hsa-Mir-4531 3

External Ids for MIR4531 Gene

Previous GeneCards Identifiers for MIR4531 Gene

  • GC19U901538
  • GC19M045157

Summaries for MIR4531 Gene

Entrez Gene Summary for MIR4531 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4531 Gene

MIR4531 (MicroRNA 4531) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4531 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4531 Gene

Genomics for MIR4531 Gene

Regulatory Elements for MIR4531 Gene

Enhancers for MIR4531 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19H044647 1.1 Ensembl ENCODE dbSUPER 0.7 +5.0 4957 3.1 ZNF664 SCRT2 HNF4G ZSCAN29 HNF4A REST PVR CEACAM19 CEACAM22P MIR4531
GH19H044657 0.8 ENCODE 0.7 -3.8 -3764 0.7 HDGF CTCF PKNOX1 RB1 MAX ARID4B RAD21 CC2D1A ZFHX2 CTBP1 PVR CEACAM19 MIR4531
GH19H044653 0.8 ENCODE 0.7 -0.6 -561 1.5 HDAC1 CTCF PKNOX1 BACH1 MAX ZMYM3 SIN3A EBF1 RAD21 CTBP1 PVR CEACAM19 MIR4531
GH19H044646 0.8 ENCODE dbSUPER 0.4 +7.4 7399 0.4 BCOR ZMYM3 ZBTB33 KDM1A CEACAM19 PVR MIR4531
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4531 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4531 Gene

Genomic Locations for MIR4531 Gene
47 bases
Minus strand

Genomic View for MIR4531 Gene

Genes around MIR4531 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4531 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4531 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4531 Gene

Proteins for MIR4531 Gene

Post-translational modifications for MIR4531 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4531 Gene

Domains & Families for MIR4531 Gene

Gene Families for MIR4531 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4531: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4531 Gene

Function for MIR4531 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4531 Gene

Localization for MIR4531 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4531 Gene

Pathways & Interactions for MIR4531 Gene

SuperPathways for MIR4531 Gene

No Data Available

Interacting Proteins for MIR4531 Gene

Gene Ontology (GO) - Biological Process for MIR4531 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4531 Gene

Drugs & Compounds for MIR4531 Gene

No Compound Related Data Available

Transcripts for MIR4531 Gene

mRNA/cDNA for MIR4531 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4531 Gene

No ASD Table

Relevant External Links for MIR4531 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4531 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4531 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4531 Gene

Orthologs for MIR4531 Gene

Evolution for MIR4531 Gene

Gene Tree for MIR4531 (if available)
Gene Tree for MIR4531 (if available)

No data available for Orthologs for MIR4531 Gene

Paralogs for MIR4531 Gene

No data available for Paralogs for MIR4531 Gene

Variants for MIR4531 Gene

Sequence variations from dbSNP and Humsavar for MIR4531 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000114397 -- 44,653,791(+) TCCCG(C/G)TGTTT intron-variant, upstream-variant-2KB
rs1002515322 -- 44,655,015(+) GAGCA(A/G)GGTAA intron-variant, upstream-variant-2KB
rs1002617032 -- 44,654,704(+) ACATC(A/G)TTTGT intron-variant, upstream-variant-2KB
rs1005188409 -- 44,655,333(+) ATCAA(C/T)CCACC intron-variant, upstream-variant-2KB
rs1006183958 -- 44,654,464(+) GAGGC(A/G)TTTAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4531 Gene

Variant ID Type Subtype PubMed ID
nsv483005 CNV loss 15286789
nsv1062812 CNV gain 25217958

Relevant External Links for MIR4531 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4531 Gene

Disorders for MIR4531 Gene

Relevant External Links for MIR4531

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4531 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4531 Gene

Publications for MIR4531 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4531 Gene

Sources for MIR4531 Gene

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