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Aliases for MIR4530 Gene

Subcategory (RNA class) for MIR4530 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4530 Gene

  • MicroRNA 4530 2 3 5
  • Hsa-Mir-4530 3

External Ids for MIR4530 Gene

Previous GeneCards Identifiers for MIR4530 Gene

  • GC19U901541
  • GC19M039901
  • GC19M039411
  • GC19M039413
  • GC19M039467

Summaries for MIR4530 Gene

Entrez Gene Summary for MIR4530 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4530 Gene

MIR4530 (MicroRNA 4530) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4530 Gene

Genomics for MIR4530 Gene

Regulatory Elements for MIR4530 Gene

Enhancers for MIR4530 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F039397 1.3 FANTOM5 ENCODE 0.8 +2.6 2604 20.0 MLX CREB3L1 ZFP64 YBX1 FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 FBL ZFP36 RPS16 RN7SL566P EID2B ENSG00000269688 SUPT5H ENSG00000205041 ENSG00000269069 EID2
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4530 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4530 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000346473 1278 4401 HDGF PKNOX1 ARNT MLX WRNIP1 ZFP64 ARID4B SIN3A YBX1 FEZF1

Genomic Location for MIR4530 Gene

Chromosome:
19
Start:
39,409,623 bp from pter
End:
39,409,678 bp from pter
Size:
56 bases
Orientation:
Minus strand

Genomic View for MIR4530 Gene

Genes around MIR4530 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4530 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4530 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4530 Gene

Proteins for MIR4530 Gene

Post-translational modifications for MIR4530 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4530 Gene

Domains & Families for MIR4530 Gene

Gene Families for MIR4530 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4530: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4530 Gene

Function for MIR4530 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4530 Gene

Localization for MIR4530 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4530 Gene

Pathways & Interactions for MIR4530 Gene

SuperPathways for MIR4530 Gene

No Data Available

Interacting Proteins for MIR4530 Gene

Gene Ontology (GO) - Biological Process for MIR4530 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4530 Gene

Transcripts for MIR4530 Gene

mRNA/cDNA for MIR4530 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4530 Gene

No ASD Table

Relevant External Links for MIR4530 Gene

GeneLoc Exon Structure for
MIR4530
ECgene alternative splicing isoforms for
MIR4530

Expression for MIR4530 Gene

mRNA expression in normal human tissues for MIR4530 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4530 Gene:

MIR4530
genes like me logo Genes that share expression patterns with MIR4530: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4530 Gene

Orthologs for MIR4530 Gene

Evolution for MIR4530 Gene

ENSEMBL:
Gene Tree for MIR4530 (if available)
TreeFam:
Gene Tree for MIR4530 (if available)

No data available for Orthologs for MIR4530 Gene

Paralogs for MIR4530 Gene

No data available for Paralogs for MIR4530 Gene

Variants for MIR4530 Gene

Sequence variations from dbSNP and Humsavar for MIR4530 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs11083522 -- 39,410,971(+) GGCAC(C/T)TCTCA upstream-variant-2KB
rs118169687 -- 39,411,402(+) TCATC(C/T)ATAGG upstream-variant-2KB
rs12980018 -- 39,410,783(+) GGATC(A/G)GGCGA upstream-variant-2KB
rs140228637 -- 39,410,843(+) AAGAG(C/T)AAGCA upstream-variant-2KB
rs140696815 -- 39,411,529(+) CTGCT(C/G)TTGCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4530 Gene

Variant ID Type Subtype PubMed ID
esv3644328 CNV loss 21293372

Relevant External Links for MIR4530 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4530

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4530 Gene

Disorders for MIR4530 Gene

Relevant External Links for MIR4530

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4530

No disorders were found for MIR4530 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4530 Gene

Publications for MIR4530 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4530 Gene

Sources for MIR4530 Gene

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