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Aliases for MIR4529 Gene

Subcategory (RNA class) for MIR4529 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4529 Gene

  • MicroRNA 4529 2 3 5
  • Hsa-Mir-4529 3

External Ids for MIR4529 Gene

Previous GeneCards Identifiers for MIR4529 Gene

  • GC18U900671
  • GC18P053150

Summaries for MIR4529 Gene

Entrez Gene Summary for MIR4529 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4529 Gene

MIR4529 (MicroRNA 4529) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4529 Gene

Genomics for MIR4529 Gene

Regulatory Elements for MIR4529 Gene

Enhancers for MIR4529 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH18G055488 1.2 Ensembl ENCODE dbSUPER 0.4 +9.9 9895 1.8 MTA2 BHLHE40 JUNB FEZF1 REST CHD7 RAD21 TBX21 ZNF692 IKZF1 TCF4-AS2 MIR4529
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4529 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4529 Gene

Chromosome:
18
Start:
55,479,221 bp from pter
End:
55,479,298 bp from pter
Size:
78 bases
Orientation:
Plus strand

Genomic View for MIR4529 Gene

Genes around MIR4529 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4529 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4529 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4529 Gene

Proteins for MIR4529 Gene

Post-translational modifications for MIR4529 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4529 Gene

Domains & Families for MIR4529 Gene

Gene Families for MIR4529 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4529: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4529 Gene

Function for MIR4529 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4529 Gene

Localization for MIR4529 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4529 Gene

Pathways & Interactions for MIR4529 Gene

SuperPathways for MIR4529 Gene

No Data Available

Interacting Proteins for MIR4529 Gene

Gene Ontology (GO) - Biological Process for MIR4529 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4529 Gene

Drugs & Compounds for MIR4529 Gene

No Compound Related Data Available

Transcripts for MIR4529 Gene

mRNA/cDNA for MIR4529 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4529 Gene

No ASD Table

Relevant External Links for MIR4529 Gene

GeneLoc Exon Structure for
MIR4529
ECgene alternative splicing isoforms for
MIR4529

Expression for MIR4529 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4529 Gene:

MIR4529
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4529 Gene

Orthologs for MIR4529 Gene

Evolution for MIR4529 Gene

ENSEMBL:
Gene Tree for MIR4529 (if available)
TreeFam:
Gene Tree for MIR4529 (if available)

No data available for Orthologs for MIR4529 Gene

Paralogs for MIR4529 Gene

No data available for Paralogs for MIR4529 Gene

Variants for MIR4529 Gene

Sequence variations from dbSNP and Humsavar for MIR4529 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type
rs1002058368 -- 55,477,649(+) CTAGC(A/G)GGACA intron-variant, upstream-variant-2KB
rs1003699970 -- 55,478,834(+) TGCAA(A/C)AAACA intron-variant, upstream-variant-2KB
rs1003731092 -- 55,479,326(+) GCTCA(A/G)CCTCT intron-variant, downstream-variant-500B
rs1003744843 -- 55,478,556(+) ACAAA(A/C)GAAAC intron-variant, upstream-variant-2KB
rs1003960822 -- 55,478,971(+) AAATA(C/T)GGCAA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4529 Gene

Variant ID Type Subtype PubMed ID
nsv1120116 OTHER inversion 24896259

Relevant External Links for MIR4529 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4529

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4529 Gene

Disorders for MIR4529 Gene

Relevant External Links for MIR4529

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4529

No disorders were found for MIR4529 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4529 Gene

Publications for MIR4529 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4529 Gene

Sources for MIR4529 Gene

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