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Aliases for MIR4524B Gene

Subcategory (RNA class) for MIR4524B Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4524B Gene

  • MicroRNA 4524b 2 3 5
  • Hsa-Mir-4524b 3

External Ids for MIR4524B Gene

Previous GeneCards Identifiers for MIR4524B Gene

  • GC17U901669
  • GC17P067098

Summaries for MIR4524B Gene

Entrez Gene Summary for MIR4524B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4524B Gene

MIR4524B (MicroRNA 4524b) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4524B Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4524B Gene

Genomics for MIR4524B Gene

GeneHancer (GH) Regulatory Elements for MIR4524B Gene

Promoters and enhancers for MIR4524B Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I069099 Enhancer 0.4 FANTOM5 550.8 +0.2 159 0.1 CREB1 MIR4524A MIR4524B ABCA6 ABCA9 ABCA10 GC17M069120
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4524B on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4524B Gene

Genomic Locations for MIR4524B Gene
chr17:69,099,542-69,099,656
(GRCh38/hg38)
Size:
115 bases
Orientation:
Plus strand
chr17:67,095,683-67,095,797
(GRCh37/hg19)

Genomic View for MIR4524B Gene

Genes around MIR4524B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4524B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4524B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4524B Gene

Proteins for MIR4524B Gene

Post-translational modifications for MIR4524B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4524B Gene

Domains & Families for MIR4524B Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4524B Gene

Function for MIR4524B Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4524B Gene

Localization for MIR4524B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4524B Gene

Pathways & Interactions for MIR4524B Gene

SuperPathways for MIR4524B Gene

No Data Available

Interacting Proteins for MIR4524B Gene

Gene Ontology (GO) - Biological Process for MIR4524B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4524B Gene

Drugs & Compounds for MIR4524B Gene

No Compound Related Data Available

Transcripts for MIR4524B Gene

mRNA/cDNA for MIR4524B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4524B Gene

No ASD Table

Relevant External Links for MIR4524B Gene

GeneLoc Exon Structure for
MIR4524B
ECgene alternative splicing isoforms for
MIR4524B

Expression for MIR4524B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4524B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4524B Gene:

MIR4524B
genes like me logo Genes that share expression patterns with MIR4524B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4524B Gene

Orthologs for MIR4524B Gene

Evolution for MIR4524B Gene

ENSEMBL:
Gene Tree for MIR4524B (if available)
TreeFam:
Gene Tree for MIR4524B (if available)

No data available for Orthologs for MIR4524B Gene

Paralogs for MIR4524B Gene

No data available for Paralogs for MIR4524B Gene

Variants for MIR4524B Gene

Sequence variations from dbSNP and Humsavar for MIR4524B Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1002575465 -- 69,098,054(+) T/G upstream_transcript_variant
rs1005015253 -- 69,099,886(+) G/A downstream_transcript_variant
rs1005567259 -- 69,099,258(+) A/G upstream_transcript_variant
rs1006579153 -- 69,098,539(+) C/T upstream_transcript_variant
rs1008666593 -- 69,100,104(+) T/C downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4524B Gene

Variant ID Type Subtype PubMed ID
nsv470598 CNV loss 18288195
nsv833526 CNV gain 17160897

Additional Variant Information for MIR4524B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4524B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4524B Gene

Disorders for MIR4524B Gene

Additional Disease Information for MIR4524B

No disorders were found for MIR4524B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4524B Gene

Publications for MIR4524B Gene

  1. Deep sequencing of short RNAs reveals novel microRNAs in minor salivary glands of patients with Sjögren's syndrome. (PMID: 21895886) Tandon M … Alevizos I (Oral diseases 2012) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4524B Gene

Sources for MIR4524B Gene

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