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Aliases for MIR4520-2 Gene

Subcategory (RNA class) for MIR4520-2 Gene


Quality Score for this RNA gene is


Aliases for MIR4520-2 Gene

  • MicroRNA 4520-2 2 3 5
  • MicroRNA 4520b 2 3
  • Hsa-Mir-4520-2 3
  • Hsa-Mir-4520b 3
  • Mir-4520-2 3
  • MIR4520B 3

External Ids for MIR4520-2 Gene

Previous HGNC Symbols for MIR4520-2 Gene

  • MIR4520B

Summaries for MIR4520-2 Gene

Entrez Gene Summary for MIR4520-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4520-2 Gene

MIR4520-2 (MicroRNA 4520-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4520-2 Gene

Genomics for MIR4520-2 Gene

Regulatory Elements for MIR4520-2 Gene

Enhancers for MIR4520-2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17F006655 0.7 ENCODE 0.8 -0.3 -333 0.2 ZNF263 CTCF MAZ RFX1 RNF2 SP2 ZNF341 ZNF600 ZBTB26 ZBTB20 MIR4520-2 ENSG00000261996
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4520-2 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4520-2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001804715 1851 601 ZNF263 SUZ12 NFXL1 ZIC2 ZBTB40 GABPA ZNF791 ZFHX2 ZNF366 HDAC2

Genomic Location for MIR4520-2 Gene

6,655,449 bp from pter
6,655,502 bp from pter
54 bases
Plus strand

Genomic View for MIR4520-2 Gene

Genes around MIR4520-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4520-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4520-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4520-2 Gene

Proteins for MIR4520-2 Gene

Post-translational modifications for MIR4520-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4520-2 Gene

Domains & Families for MIR4520-2 Gene

Gene Families for MIR4520-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4520-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4520-2 Gene

Function for MIR4520-2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4520-2 Gene

Localization for MIR4520-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4520-2 Gene

Pathways & Interactions for MIR4520-2 Gene

SuperPathways for MIR4520-2 Gene

No Data Available

Interacting Proteins for MIR4520-2 Gene

Gene Ontology (GO) - Biological Process for MIR4520-2 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4520-2 Gene

Transcripts for MIR4520-2 Gene

mRNA/cDNA for MIR4520-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4520-2 Gene

No ASD Table

Relevant External Links for MIR4520-2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4520-2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4520-2 Gene

genes like me logo Genes that share expression patterns with MIR4520-2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4520-2 Gene

Orthologs for MIR4520-2 Gene

Evolution for MIR4520-2 Gene

Gene Tree for MIR4520-2 (if available)
Gene Tree for MIR4520-2 (if available)

No data available for Orthologs for MIR4520-2 Gene

Paralogs for MIR4520-2 Gene

No data available for Paralogs for MIR4520-2 Gene

Variants for MIR4520-2 Gene

Sequence variations from dbSNP and Humsavar for MIR4520-2 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs10491082 -- 6,654,268(+) ACAAA(C/T)GAGAC upstream-variant-2KB
rs10491083 -- 6,655,238(+) CCTAA(A/G)TGTAC downstream-variant-500B, upstream-variant-2KB
rs111225872 -- 6,654,177(+) GGTCT(A/G)CTGGG upstream-variant-2KB
rs111504531 -- 6,655,671(+) TCAAC(C/T)GCTAG downstream-variant-500B, upstream-variant-2KB
rs111701168 -- 6,654,236(+) AGTAA(A/T)GAGAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4520-2 Gene

Variant ID Type Subtype PubMed ID
nsv574278 CNV gain 21841781

Relevant External Links for MIR4520-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4520-2 Gene

Disorders for MIR4520-2 Gene

Relevant External Links for MIR4520-2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4520-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4520-2 Gene

Publications for MIR4520-2 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4520-2 Gene

Sources for MIR4520-2 Gene

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