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Aliases for MIR4520-1 Gene

Subcategory (RNA class) for MIR4520-1 Gene


Quality Score for this RNA gene is


Aliases for MIR4520-1 Gene

  • MicroRNA 4520-1 2 3 5
  • MicroRNA 4520a 2 3
  • Hsa-Mir-4520-1 3
  • Hsa-Mir-4520a 3
  • Mir-4520-1 3
  • MIR4520A 3

External Ids for MIR4520-1 Gene

Previous HGNC Symbols for MIR4520-1 Gene

  • MIR4520A

Summaries for MIR4520-1 Gene

Entrez Gene Summary for MIR4520-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4520-1 Gene

MIR4520-1 (MicroRNA 4520-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4520-1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4520-1 Gene

Genomics for MIR4520-1 Gene

Regulatory Elements for MIR4520-1 Gene

Enhancers for MIR4520-1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17H006654 1.2 Ensembl ENCODE dbSUPER 0.7 -0.7 -692 4 CTCF ZIC2 RFX5 POLR2A ZNF600 CREM ZBTB20 EZH2 RFX1 MAZ ENSG00000261996 KIAA0753 TNK1 ENSG00000274114 MIR4520-1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4520-1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4520-1 Gene

6,655,440 bp from pter
6,655,509 bp from pter
70 bases
Minus strand

Genomic View for MIR4520-1 Gene

Genes around MIR4520-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4520-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4520-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4520-1 Gene

ORGUL Member Location for MIR4520-1 Gene

ORGUL Member Location for MIR4520-1 gene

Proteins for MIR4520-1 Gene

Post-translational modifications for MIR4520-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4520-1 Gene

Domains & Families for MIR4520-1 Gene

Gene Families for MIR4520-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4520-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4520-1 Gene

Function for MIR4520-1 Gene

Phenotypes From GWAS Catalog for MIR4520-1 Gene

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for MIR4520-1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4520-1 Gene

Localization for MIR4520-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4520-1 Gene

Pathways & Interactions for MIR4520-1 Gene

SuperPathways for MIR4520-1 Gene

No Data Available

Interacting Proteins for MIR4520-1 Gene

Gene Ontology (GO) - Biological Process for MIR4520-1 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4520-1 Gene

Drugs & Compounds for MIR4520-1 Gene

No Compound Related Data Available

Transcripts for MIR4520-1 Gene

mRNA/cDNA for MIR4520-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for MIR4520-1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4520-1 Gene

No ASD Table

Relevant External Links for MIR4520-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4520-1 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4520-1 Gene

Orthologs for MIR4520-1 Gene

Evolution for MIR4520-1 Gene

Gene Tree for MIR4520-1 (if available)
Gene Tree for MIR4520-1 (if available)

No data available for Orthologs for MIR4520-1 Gene

Paralogs for MIR4520-1 Gene

No data available for Paralogs for MIR4520-1 Gene

Variants for MIR4520-1 Gene

Sequence variations from dbSNP and Humsavar for MIR4520-1 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1000142879 -- 6,656,226(+) CGGAG(C/T)AGGTG upstream-variant-2KB
rs1001097596 -- 6,655,077(+) GCCCG(C/G)GCTGG downstream-variant-500B, upstream-variant-2KB
rs1004458242 -- 6,655,004(+) TCCCT(C/T)TTGCG downstream-variant-500B, upstream-variant-2KB
rs1004635220 -- 6,655,414(+) ACCTC(-/GCCT)GCCTG downstream-variant-500B, upstream-variant-2KB
rs1008812708 -- 6,655,717(+) TGGGG(G/T)GGAGT downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4520-1 Gene

Variant ID Type Subtype PubMed ID
nsv574278 CNV gain 21841781

Relevant External Links for MIR4520-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4520-1 Gene

Disorders for MIR4520-1 Gene

Relevant External Links for MIR4520-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4520-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4520-1 Gene

Publications for MIR4520-1 Gene

  1. Differential Expression of miR-4520a Associated With Pyrin Mutations in Familial Mediterranean Fever (FMF). (PMID: 27636101) Latsoudis H … Goulielmos GN (Journal of cellular physiology 2016) 3 60
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  4. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce CE … Bowcock AM (Human molecular genetics 2011) 3 60
  5. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 60

Products for MIR4520-1 Gene

Sources for MIR4520-1 Gene

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