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Aliases for MIR452 Gene

Subcategory (RNA class) for MIR452 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR452 Gene

  • MicroRNA 452 2 3
  • Hsa-Mir-452 3
  • MIRN452 3

External Ids for MIR452 Gene

Previous Symbols for MIR452 Gene

  • MIRN452

Summaries for MIR452 Gene

Entrez Gene Summary for MIR452 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR452 Gene

MIR452 (MicroRNA 452) is a RNA Gene, and belongs to miRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR452 Gene

Genomics for MIR452 Gene

Genomic Location for MIR452 Gene

Start:
151,959,607 bp from pter
End:
151,959,719 bp from pter
Size:
113 bases
Orientation:
Minus strand

Genomic View for MIR452 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR452 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR452 Gene

No data available for Regulatory Elements for MIR452 Gene

Proteins for MIR452 Gene

Post-translational modifications for MIR452 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR452 Gene

Domains for MIR452 Gene

Gene Families for MIR452 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR452: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR452 Gene

Function for MIR452 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR452 Gene

Localization for MIR452 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR452 Gene

Pathways for MIR452 Gene

SuperPathways for MIR452 Gene

No Data Available

Interacting Proteins for MIR452 Gene

Gene Ontology (GO) - Biological Process for MIR452 Gene

None

No data available for Pathways by source for MIR452 Gene

Transcripts for MIR452 Gene

mRNA/cDNA for MIR452 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR452 Gene

No ASD Table

Relevant External Links for MIR452 Gene

GeneLoc Exon Structure for
MIR452
ECgene alternative splicing isoforms for
MIR452

Expression for MIR452 Gene

mRNA expression in normal human tissues for MIR452 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

genes like me logo Genes that share expressions with MIR452: view

Orthologs for MIR452 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR452 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-452 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-452 37
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-452 37
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir452 37
  • 96 (a)
OneToOne
Species with no ortholog for MIR452:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR452 Gene

ENSEMBL:
Gene Tree for MIR452 (if available)
TreeFam:
Gene Tree for MIR452 (if available)

Paralogs for MIR452 Gene

No data available for Paralogs for MIR452 Gene

Variants for MIR452 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR452 Gene

Variant ID Type Subtype PubMed ID
nsv510867 CNV Loss 20534489

Relevant External Links for MIR452 Gene

HapMap Linkage Disequilibrium report
MIR452

No data available for Sequence variations from dbSNP and Humsavar for MIR452 Gene

Disorders for MIR452 Gene

No disorders were found for MIR452 Gene.

No data available for UniProtKB/Swiss-Prot for MIR452 Gene

Publications for MIR452 Gene

  1. Clustering and conservation patterns of human microRNAs. (PMID: 15891114) Altuvia Y. … Margalit H. (Nucleic Acids Res. 2005) 3
  2. Identification of hundreds of conserved and nonconserved human microRNAs. (PMID: 15965474) Bentwich I. … Bentwich Z. (Nat. Genet. 2005) 3
  3. Identification of clustered microRNAs using an ab initio prediction method. (PMID: 16274478) Sewer A. … Zavolan M. (BMC Bioinformatics 2005) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3

Products for MIR452 Gene

Sources for MIR452 Gene

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