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Aliases for MIR451B Gene

Subcategory (RNA class) for MIR451B Gene


Quality Score for this RNA gene is


Aliases for MIR451B Gene

  • MicroRNA 451b 2 3
  • Hsa-Mir-451b 3

External Ids for MIR451B Gene

ORGUL Members for MIR451B Gene

Previous GeneCards Identifiers for MIR451B Gene

  • GC17U901655
  • GC17M027195
  • GC17P027190

Summaries for MIR451B Gene

Entrez Gene Summary for MIR451B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR451B Gene

MIR451B (MicroRNA 451b) is an RNA Gene, and is affiliated with the lncRNA class.

fRNAdb sequence ontologies for MIR451B Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR451B

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR451B Gene

Genomics for MIR451B Gene

Genomic Location for MIR451B Gene

28,861,371 bp from pter
28,861,438 bp from pter
68 bases
Plus strand

Genomic View for MIR451B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR451B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR451B Gene

ORGUL Member Location for MIR451B Gene

ORGUL Member Location for MIR451B gene

No data available for Regulatory Elements for MIR451B Gene

Proteins for MIR451B Gene

Post-translational modifications for MIR451B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR451B Gene

Domains for MIR451B Gene

Gene Families for MIR451B Gene

  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR451B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR451B Gene

Function for MIR451B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR451B Gene

Localization for MIR451B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR451B Gene

Pathways for MIR451B Gene

SuperPathways for MIR451B Gene

No Data Available

Interacting Proteins for MIR451B Gene

Gene Ontology (GO) - Biological Process for MIR451B Gene


No data available for Pathways by source for MIR451B Gene

Transcripts for MIR451B Gene

fRNAdb Secondary structures for MIR451B Gene

  • FR102080

mRNA/cDNA for MIR451B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR451B Gene

No ASD Table

Relevant External Links for MIR451B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR451B Gene

mRNA expression in normal human tissues for MIR451B Gene

genes like me logo Genes that share expressions with MIR451B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR451B Gene

Orthologs for MIR451B Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR451B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-144 36
  • 92 (a)
(Canis familiaris)
Mammalia cfa-mir-144 36
  • 93 (a)
(Monodelphis domestica)
Mammalia mdo-mir-144 36
  • 86 (a)
(Mus musculus)
Mammalia Mir144 36
  • 98 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-144 36
  • 58 (a)
(Pan troglodytes)
Mammalia ptr-mir-144 36
  • 99 (a)
(Gallus gallus)
Aves gga-mir-144 36
  • 80 (a)
(Danio rerio)
Actinopterygii dre-mir-144 36
  • 72 (a)
Species with no ortholog for MIR451B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR451B Gene

Gene Tree for MIR451B (if available)
Gene Tree for MIR451B (if available)

Paralogs for MIR451B Gene

No data available for Paralogs for MIR451B Gene

Variants for MIR451B Gene

Relevant External Links for MIR451B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR451B Gene

Disorders for MIR451B Gene

No disorders were found for MIR451B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR451B Gene

Publications for MIR451B Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3

Products for MIR451B Gene

Sources for MIR451B Gene

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