Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR4518 Gene

Subcategory (RNA class) for MIR4518 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4518 Gene

  • MicroRNA 4518 2 3 5
  • Hsa-Mir-4518 3
  • Mir-4518 3

External Ids for MIR4518 Gene

Previous GeneCards Identifiers for MIR4518 Gene

  • GC16U901347

Summaries for MIR4518 Gene

Entrez Gene Summary for MIR4518 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4518 Gene

MIR4518 (MicroRNA 4518) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4518 Gene

Genomics for MIR4518 Gene

Regulatory Elements for MIR4518 Gene

Enhancers for MIR4518 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16G030521 1.3 ENCODE dbSUPER 0.4 +18.6 18618 1.5 PKNOX1 ARID4B DMAP1 ZNF2 YY1 SLC30A9 SP3 ZHX2 MXD4 KAT8 ZNF785 ENSG00000260267 SMG1P2 ENSG00000260304 ENSG00000235560 ZNF764 ZNF48 ZNF747 ENSG00000260625 NPIPB13
GH16G030509 1.2 ENCODE dbSUPER 0.4 +6.2 6180 1.8 ELF3 ATF1 ARID4B THRB ZSCAN9 RAD21 YY1 RARA SLC30A9 ZNF121 ENSG00000235560 MIR4518 PIR36283
GH16G030524 1.3 ENCODE dbSUPER 0.3 +20.6 20563 0.3 HDGF ATF1 ARNT AGO1 ZNF2 GLIS2 ZNF143 KDM4B NFYC ZHX2 PIR36283 MIR4518
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4518 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4518 Gene

Chromosome:
16
Start:
30,503,919 bp from pter
End:
30,504,001 bp from pter
Size:
83 bases
Orientation:
Plus strand

Genomic View for MIR4518 Gene

Genes around MIR4518 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4518 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4518 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4518 Gene

Proteins for MIR4518 Gene

Post-translational modifications for MIR4518 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4518 Gene

Domains & Families for MIR4518 Gene

Gene Families for MIR4518 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4518: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4518 Gene

Function for MIR4518 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4518 Gene

Localization for MIR4518 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4518 Gene

Pathways & Interactions for MIR4518 Gene

SuperPathways for MIR4518 Gene

No Data Available

Interacting Proteins for MIR4518 Gene

Gene Ontology (GO) - Biological Process for MIR4518 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4518 Gene

Drugs & Compounds for MIR4518 Gene

No Compound Related Data Available

Transcripts for MIR4518 Gene

mRNA/cDNA for MIR4518 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4518 Gene

No ASD Table

Relevant External Links for MIR4518 Gene

GeneLoc Exon Structure for
MIR4518
ECgene alternative splicing isoforms for
MIR4518

Expression for MIR4518 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4518 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4518 Gene:

MIR4518
genes like me logo Genes that share expression patterns with MIR4518: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4518 Gene

Orthologs for MIR4518 Gene

Evolution for MIR4518 Gene

ENSEMBL:
Gene Tree for MIR4518 (if available)
TreeFam:
Gene Tree for MIR4518 (if available)

No data available for Orthologs for MIR4518 Gene

Paralogs for MIR4518 Gene

No data available for Paralogs for MIR4518 Gene

Variants for MIR4518 Gene

Sequence variations from dbSNP and Humsavar for MIR4518 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000590607 -- 30,503,841(+) TTCTA(A/G)TTATT intron-variant, upstream-variant-2KB
rs1001203678 -- 30,502,270(+) TGGGG(A/G)CCTGT intron-variant, upstream-variant-2KB
rs1001441964 -- 30,503,446(+) TTTTT(-/C)TTTTT intron-variant, upstream-variant-2KB
rs1001829508 -- 30,502,766(+) AAATT(A/C)ATATA intron-variant, upstream-variant-2KB
rs1002214443 -- 30,503,936(+) GCTGG(A/G)ATTGA intron-variant, nc-transcript-variant

Relevant External Links for MIR4518 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4518

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4518 Gene

Disorders for MIR4518 Gene

Relevant External Links for MIR4518

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4518

No disorders were found for MIR4518 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4518 Gene

Publications for MIR4518 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4518 Gene

Sources for MIR4518 Gene

Content
Loading form....