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Aliases for MIR4515 Gene

Subcategory (RNA class) for MIR4515 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4515 Gene

  • MicroRNA 4515 2 3 5
  • Hsa-Mir-4515 3
  • Mir-4515 3

External Ids for MIR4515 Gene

Previous GeneCards Identifiers for MIR4515 Gene

  • GC15U901392
  • GC15P083738
  • GC15P083096
  • GC15P083099
  • GC15P083102
  • GC15P083104
  • GC15P083111

Summaries for MIR4515 Gene

Entrez Gene Summary for MIR4515 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4515 Gene

MIR4515 (MicroRNA 4515) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4515 Gene

Genomics for MIR4515 Gene

Regulatory Elements for MIR4515 Gene

Enhancers for MIR4515 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15G083060 2 FANTOM5 Ensembl ENCODE dbSUPER 0.7 -2.6 -2613 7.5 HDGF HNRNPUL1 PKNOX1 FOXA2 ARNT CREB3L1 WRNIP1 ARID4B SIN3A FEZF1 C15orf40 BTBD1 TM6SF1 SNHG21 FAM103A1 AP3B2 GOLGA6L9 WHAMM MIR4515 GC15P083164
GH15G083052 1.1 Ensembl ENCODE dbSUPER 0.4 -13.9 -13879 1.4 FEZF1 ZNF394 EP300 PRDM6 JUND ZNF692 SCRT2 FOS TM6SF1 C15orf40 BTBD1 GOLGA6L10 GC15P083164 MIR4515
GH15G083057 0.2 dbSUPER 0.4 -9.4 -9360 1.3 FAM103A1 HOMER2 BTBD1 MIR4515 GC15P083164
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4515 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4515 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000080276 -1235 3001 HDGF HNRNPUL1 PKNOX1 FOXA2 ARNT CREB3L1 WRNIP1 ARID4B SIN3A DMAP1

Genomic Location for MIR4515 Gene

Chromosome:
15
Start:
83,067,335 bp from pter
End:
83,067,415 bp from pter
Size:
81 bases
Orientation:
Plus strand

Genomic View for MIR4515 Gene

Genes around MIR4515 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4515 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4515 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4515 Gene

Proteins for MIR4515 Gene

Post-translational modifications for MIR4515 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4515 Gene

Domains & Families for MIR4515 Gene

Gene Families for MIR4515 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4515: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4515 Gene

Function for MIR4515 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4515 Gene

Localization for MIR4515 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4515 Gene

Pathways & Interactions for MIR4515 Gene

SuperPathways for MIR4515 Gene

No Data Available

Interacting Proteins for MIR4515 Gene

Gene Ontology (GO) - Biological Process for MIR4515 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4515 Gene

Drugs & Compounds for MIR4515 Gene

No Compound Related Data Available

Transcripts for MIR4515 Gene

mRNA/cDNA for MIR4515 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4515 Gene

No ASD Table

Relevant External Links for MIR4515 Gene

GeneLoc Exon Structure for
MIR4515
ECgene alternative splicing isoforms for
MIR4515

Expression for MIR4515 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4515 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4515 Gene:

MIR4515
genes like me logo Genes that share expression patterns with MIR4515: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4515 Gene

Orthologs for MIR4515 Gene

Evolution for MIR4515 Gene

ENSEMBL:
Gene Tree for MIR4515 (if available)
TreeFam:
Gene Tree for MIR4515 (if available)

No data available for Orthologs for MIR4515 Gene

Paralogs for MIR4515 Gene

No data available for Paralogs for MIR4515 Gene

Variants for MIR4515 Gene

Sequence variations from dbSNP and Humsavar for MIR4515 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1000324989 -- 83,065,578(+) TACCC(A/T)AGACT intron-variant, upstream-variant-2KB
rs1001467383 -- 83,067,276(+) CCTCC(A/G)CAGGC nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime
rs1003084794 -- 83,066,321(+) AGGGG(A/G)TGACA intron-variant, upstream-variant-2KB
rs1003493971 -- 83,065,983(+) TTAAT(A/G)AAAAA intron-variant, upstream-variant-2KB
rs1003536776 -- 83,066,173(+) GCGTG(C/T)CTGTA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4515 Gene

Variant ID Type Subtype PubMed ID
nsv1120052 OTHER inversion 24896259
nsv7269 OTHER inversion 18451855

Relevant External Links for MIR4515 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4515

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4515 Gene

Disorders for MIR4515 Gene

Relevant External Links for MIR4515

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4515

No disorders were found for MIR4515 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4515 Gene

Publications for MIR4515 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4515 Gene

Sources for MIR4515 Gene

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