Aliases for MIR4514 Gene
Subcategory (RNA class) for MIR4514 Gene
miRNA
Quality Score for this RNA gene is
8
External Ids for MIR4514 Gene
- HGNC: 41845
- Entrez Gene: 100616181
- Ensembl: ENSG00000265855
- miRBase: hsa-mir-4514
ORGUL Members for MIR4514 Gene
Previous GeneCards Identifiers for MIR4514 Gene
- GC15U901404
- GC15M081291
Summaries for MIR4514 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR4514 Gene
MIR4514 (MicroRNA 4514) is an RNA Gene, and is affiliated with the miRNA class.
No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4514 Gene
Genomics for MIR4514 Gene
Regulatory Element Products
Genomic Location for MIR4514 Gene
- Chromosome:
- 15
- Start:
- 80,997,417 bp from pter
- End:
- 80,997,473 bp from pter
- Size:
- 57 bases
- Orientation:
- Minus strand
Genomic View for MIR4514 Gene
Genes around MIR4514 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 15q25.1 by Ensembl
- 15q25.1 by Entrez Gene
- 15q25.1 by HGNC
MIR4514 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR4514 Gene
ORGUL Member Location for MIR4514 Gene
No data available for Regulatory Elements for MIR4514 Gene
Proteins for MIR4514 Gene
Post-translational modifications for MIR4514 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MIR4514
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR4514
- Origene Custom Protein Services for MIR4514
- Search GeneTex for Proteins for MIR4514
Assay Products
No data available for DME Specific Peptides for MIR4514 Gene
Domains & Families for MIR4514 Gene
Gene Families for MIR4514 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4514 Gene
Function for MIR4514 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR4514
-
- Search ViGene Biosciences for MIR4514
CRISPR Products
- Browse CRISPR knockouts for MIR4514
Inhibitory RNA Products
- Search ViGene Biosciences for MIR4514
Clone Products
- GenScript: Custom all cDNA clones Services for MIR4514
- VectorBuilder custom plasmid, inducible vectors for MIR4514
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4514
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
- Search ViGene Biosciences for MIR4514
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4514 Gene
Localization for MIR4514 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4514 Gene
Transcripts for MIR4514 Gene
mRNA/cDNA for MIR4514 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR4514
Inhibitory RNA Products
- Search ViGene Biosciences for MIR4514
Clone Products
- GenScript: Custom all cDNA clones Services for MIR4514
- VectorBuilder custom plasmid, inducible vectors for MIR4514
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4514
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for MIR4514 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR4514 Gene:
MIR4514
No Expression Related Data Available
Primer Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4514 Gene
Orthologs for MIR4514 Gene
No data available for Orthologs for MIR4514 Gene
Paralogs for MIR4514 Gene
No data available for Paralogs for MIR4514 Gene
Variants for MIR4514 Gene
| SNP ID | Clin | Chr 15 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs10162964 | -- | 80,998,078(+) | atttt(A/G)atttt | upstream-variant-2KB | |
| rs112585854 | -- | 80,999,045(+) | TATTT(A/T)TTTTT | upstream-variant-2KB | |
| rs113605253 | -- | 80,996,931(+) | GTGGG(C/T)GCCTG | downstream-variant-500B | |
| rs11437837 | -- | 80,997,700(+) | AAAAA(-/A)TACTT | upstream-variant-2KB | |
| rs116034786 | -- | 80,997,457(+) | CCCCA(A/G)TCCTG | nc-transcript-variant |
Relevant External Links for MIR4514 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR4514
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4514 Gene
Disorders for MIR4514 Gene
Relevant External Links for MIR4514
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- MIR4514
No disorders were found for MIR4514 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4514 Gene
Publications for MIR4514 Gene
- Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
Products for MIR4514 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR4514
- Origene Custom Protein Services for MIR4514
- Browse OriGene Inhibitory RNA Products For MIR4514
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for MIR4514
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MIR4514
- GenScript: Custom all cDNA clones Services for MIR4514
- GenScript Custom Purified and Recombinant Proteins Services for MIR4514
- GenScript Custom Assay Services for MIR4514
- GenScript Custom overexpressing Cell Line Services for MIR4514
- Browse GenScript CRISPR for MIR4514
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for MIR4514
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Search ViGene Biosciences for MIR4514
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR4514
- VectorBuilder custom plasmid, inducible vectors for MIR4514
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4514
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for MIR4514 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab