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MIR4514 Gene(RNA Gene)

MicroRNA 4514

GCID:
GC15M080997
GIFtS:
11
Genes Participants
UDN Logo

Aliases for MIR4514 Gene

Subcategory (RNA class) for MIR4514 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4514 Gene

  • MicroRNA 4514 2 3 5
  • Hsa-Mir-4514 3

External Ids for MIR4514 Gene

ORGUL Members for MIR4514 Gene

Previous GeneCards Identifiers for MIR4514 Gene

  • GC15U901404
  • GC15M081291

Summaries for MIR4514 Gene

Entrez Gene Summary for MIR4514 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4514 Gene

MIR4514 (MicroRNA 4514) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4514 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4514 Gene

Genomics for MIR4514 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for MIR4514 Gene

Promoters and enhancers for MIR4514 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH15I080998 Enhancer 0.8 Ensembl dbSUPER 550.8 -1.3 -1328 0.4 BCOR IRF2 L3MBTL2 HLF USF2 REST NFIL3 ZNF766 POLR2A PRDM10 MIR4514 ENSG00000277782
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4514 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4514 Gene

Genomic Locations for MIR4514 Gene
chr15:80,997,417-80,997,473
(GRCh38/hg38)
Size:
57 bases
Orientation:
Minus strand
chr15:81,289,758-81,289,814
(GRCh37/hg19)

Genomic View for MIR4514 Gene

Genes around MIR4514 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4514 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4514 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR4514 Gene

ORGUL Member Location for MIR4514 Gene

ORGUL Member Location for MIR4514 gene

Proteins for MIR4514 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR4514 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4514 Gene

Domains & Families for MIR4514 Gene

Gene Families for MIR4514 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4514: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4514 Gene

Function for MIR4514 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4514 Gene

Localization for MIR4514 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4514 Gene

Pathways & Interactions for MIR4514 Gene

SuperPathways for MIR4514 Gene

PathCards logo More details on SuperPathways for MIR4514
No Data Available

Interacting Proteins for MIR4514 Gene

Gene Ontology (GO) - Biological Process for MIR4514 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4514 Gene

Drugs & Compounds for MIR4514 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR4514 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for MIR4514 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4514 Gene

No ASD Table

Relevant External Links for MIR4514 Gene

GeneLoc Exon Structure for
MIR4514
ECgene alternative splicing isoforms for
MIR4514

Expression for MIR4514 Gene

Products:

  1. Primer

NURSA nuclear receptor signaling pathways regulating expression of MIR4514 Gene:

MIR4514
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4514 Gene

Orthologs for MIR4514 Gene

Evolution for MIR4514 Gene

ENSEMBL:
Gene Tree for MIR4514 (if available)
TreeFam:
Gene Tree for MIR4514 (if available)

No data available for Orthologs for MIR4514 Gene

Paralogs for MIR4514 Gene

No data available for Paralogs for MIR4514 Gene

Variants for MIR4514 Gene

Sequence variations from dbSNP and Humsavar for MIR4514 Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1002361611 -- 80,999,372(-) G/A upstream_transcript_variant
rs1002412511 -- 80,999,137(-) T/C/G upstream_transcript_variant
rs1002457257 -- 80,998,818(-) A/T upstream_transcript_variant
rs1004639787 -- 80,997,442(-) A/G non_coding_transcript_variant
rs1006361376 -- 80,998,734(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4514 Gene

Variant ID Type Subtype PubMed ID
nsv1637 CNV deletion 18451855

Additional Variant Information for MIR4514 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4514

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4514 Gene

Disorders for MIR4514 Gene

Additional Disease Information for MIR4514

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR4514 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4514 Gene

Publications for MIR4514 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4514 Gene

Sources for MIR4514 Gene

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