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Aliases for MIR4513 Gene

Subcategory (RNA class) for MIR4513 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4513 Gene

  • MicroRNA 4513 2 3 5
  • Hsa-Mir-4513 3

External Ids for MIR4513 Gene

Previous GeneCards Identifiers for MIR4513 Gene

  • GC15U901403
  • GC15M075083

Summaries for MIR4513 Gene

Entrez Gene Summary for MIR4513 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4513 Gene

MIR4513 (MicroRNA 4513) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4513 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4513 Gene

Genomics for MIR4513 Gene

GeneHancer (GH) Regulatory Elements for MIR4513 Gene

Promoters and enhancers for MIR4513 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I074775 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 550.8 +0.6 584 26 DMAP1 IRF4 YY1 SLC30A9 ZNF143 ZNF263 SP3 MEF2D GLIS1 RCOR2 CSK MIR4513 EDC3 SIN3A LOC441728 ULK3 ENSG00000260274 C15orf39 DNM1P35 ENSG00000203392
GH15I074808 Enhancer 0.8 ENCODE dbSUPER 0.4 -19.7 -19690 0.7 SMARCA5 MAX CEBPB CEBPG RFX5 ATF4 HDAC2 POLR2A TRIM24 KDM1A SCAMP5 LOC283731 LMAN1L MIR4513
GH15I074803 Enhancer 0.6 dbSUPER 0.4 -15.4 -15365 1.6 SCRT1 ZNF680 ZNF189 SMAD5 ZIC2 SSRP1 ZFP36 PRDM10 BCLAF1 ULK3 CPLX3 RPP25 LMAN1L MIR4513
GH15I074809 Enhancer 0.8 ENCODE dbSUPER 0.3 -20.3 -20328 0.2 SMARCA5 BCOR CTCF ZNF175 ZMYM3 CEBPG RAD21 HDAC2 KDM1A DNM1P35 MAN2C1 LOC441728 EDC3 LMAN1L MIR4513
GH15I074806 Enhancer 0.5 dbSUPER 0.4 -18.5 -18458 1.3 ZNF366 CBFA2T3 ZSCAN29 KDM1A ZIC2 RFX5 CPLX3 LOC283731 RPP25 LMAN1L MIR4513
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4513 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4513 Gene

Genomic Locations for MIR4513 Gene
chr15:74,788,672-74,788,757
(GRCh38/hg38)
Size:
86 bases
Orientation:
Minus strand
chr15:75,081,013-75,081,098
(GRCh37/hg19)

Genomic View for MIR4513 Gene

Genes around MIR4513 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4513 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4513 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4513 Gene

Proteins for MIR4513 Gene

Post-translational modifications for MIR4513 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4513 Gene

Domains & Families for MIR4513 Gene

Gene Families for MIR4513 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4513: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4513 Gene

Function for MIR4513 Gene

Phenotypes From GWAS Catalog for MIR4513 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4513 Gene

Localization for MIR4513 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4513 Gene

Pathways & Interactions for MIR4513 Gene

SuperPathways for MIR4513 Gene

No Data Available

Interacting Proteins for MIR4513 Gene

Gene Ontology (GO) - Biological Process for MIR4513 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4513 Gene

Drugs & Compounds for MIR4513 Gene

No Compound Related Data Available

Transcripts for MIR4513 Gene

mRNA/cDNA for MIR4513 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4513 Gene

No ASD Table

Relevant External Links for MIR4513 Gene

GeneLoc Exon Structure for
MIR4513
ECgene alternative splicing isoforms for
MIR4513

Expression for MIR4513 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4513 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4513 Gene:

MIR4513
genes like me logo Genes that share expression patterns with MIR4513: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4513 Gene

Orthologs for MIR4513 Gene

Evolution for MIR4513 Gene

ENSEMBL:
Gene Tree for MIR4513 (if available)
TreeFam:
Gene Tree for MIR4513 (if available)

No data available for Orthologs for MIR4513 Gene

Paralogs for MIR4513 Gene

No data available for Paralogs for MIR4513 Gene

Variants for MIR4513 Gene

Sequence variations from dbSNP and Humsavar for MIR4513 Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000384307 -- 74,788,984(-) C/A upstream_transcript_variant
rs1003116592 -- 74,790,663(-) T/C upstream_transcript_variant
rs1003517392 -- 74,789,820(-) T/C upstream_transcript_variant
rs1006170539 -- 74,789,851(-) A/T upstream_transcript_variant
rs1007082069 -- 74,788,238(-) CAAGCAAG/CAAG downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4513 Gene

Variant ID Type Subtype PubMed ID
nsv1121512 CNV deletion 24896259
nsv833055 CNV loss 17160897

Additional Variant Information for MIR4513 Gene

Human Gene Mutation Database (HGMD)
MIR4513
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4513

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4513 Gene

Disorders for MIR4513 Gene

Additional Disease Information for MIR4513

No disorders were found for MIR4513 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4513 Gene

Publications for MIR4513 Gene

  1. A genetic variant in the seed region of miR-4513 shows pleiotropic effects on lipid and glucose homeostasis, blood pressure, and coronary artery disease. (PMID: 25256095) Ghanbari M … Dehghan A (Human mutation 2014) 3 58
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4513 Gene

Sources for MIR4513 Gene

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