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Aliases for MIR4512 Gene

Subcategory (RNA class) for MIR4512 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4512 Gene

  • MicroRNA 4512 2 3 5
  • Hsa-Mir-4512 3

External Ids for MIR4512 Gene

Previous GeneCards Identifiers for MIR4512 Gene

  • GC15U901412
  • GC15M066804
  • GC15M066817
  • GC15M066825

Summaries for MIR4512 Gene

Entrez Gene Summary for MIR4512 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4512 Gene

MIR4512 (MicroRNA 4512) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4512 Gene

Genomics for MIR4512 Gene

Regulatory Elements for MIR4512 Gene

Enhancers for MIR4512 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15G066495 1.2 ENCODE 0.7 -0.2 -175 3.9 CREB3L1 AGO1 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 NFYC TIPIN SNAPC5 ENSG00000260773 SLC24A1 ZWILCH SNORD16 HACD3 DIS3L LOC105370868 MIR4512
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4512 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4512 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000078183 -466 1001 CREB3L1 AGO1 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 NFYC

Genomic Location for MIR4512 Gene

Chromosome:
15
Start:
66,496,958 bp from pter
End:
66,497,034 bp from pter
Size:
77 bases
Orientation:
Minus strand

Genomic View for MIR4512 Gene

Genes around MIR4512 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4512 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4512 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4512 Gene

ORGUL Member Location for MIR4512 Gene

ORGUL Member Location for MIR4512 gene

Proteins for MIR4512 Gene

Post-translational modifications for MIR4512 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4512 Gene

Domains & Families for MIR4512 Gene

Gene Families for MIR4512 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4512: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4512 Gene

Function for MIR4512 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4512 Gene

Localization for MIR4512 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4512 Gene

Pathways & Interactions for MIR4512 Gene

SuperPathways for MIR4512 Gene

No Data Available

Interacting Proteins for MIR4512 Gene

Gene Ontology (GO) - Biological Process for MIR4512 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4512 Gene

Drugs & Compounds for MIR4512 Gene

No Compound Related Data Available

Transcripts for MIR4512 Gene

mRNA/cDNA for MIR4512 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4512 Gene

No ASD Table

Relevant External Links for MIR4512 Gene

GeneLoc Exon Structure for
MIR4512
ECgene alternative splicing isoforms for
MIR4512

Expression for MIR4512 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4512 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4512 Gene:

MIR4512
genes like me logo Genes that share expression patterns with MIR4512: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4512 Gene

Orthologs for MIR4512 Gene

Evolution for MIR4512 Gene

ENSEMBL:
Gene Tree for MIR4512 (if available)
TreeFam:
Gene Tree for MIR4512 (if available)

No data available for Orthologs for MIR4512 Gene

Paralogs for MIR4512 Gene

No data available for Paralogs for MIR4512 Gene

Variants for MIR4512 Gene

Sequence variations from dbSNP and Humsavar for MIR4512 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1000114741 -- 66,498,688(+) ACCTC(C/T)CAGGT upstream-variant-2KB
rs1000615099 -- 66,497,138(+) TCCAG(A/G)CGTTA intron-variant, upstream-variant-2KB
rs1000964707 -- 66,497,350(+) GGCGA(C/T)GAACA intron-variant, upstream-variant-2KB
rs1001567249 -- 66,497,872(+) CCCCT(C/T)CCGGC upstream-variant-2KB
rs1001671524 -- 66,498,952(+) AAAAA(C/G)AACAC downstream-variant-500B, upstream-variant-2KB

Relevant External Links for MIR4512 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4512

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4512 Gene

Disorders for MIR4512 Gene

Relevant External Links for MIR4512

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4512

No disorders were found for MIR4512 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4512 Gene

Publications for MIR4512 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4512 Gene

Sources for MIR4512 Gene

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