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Aliases for MIR4509-1 Gene

Subcategory (RNA class) for MIR4509-1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4509-1 Gene

  • MicroRNA 4509-1 2 3 5
  • Hsa-Mir-4509-1 3

External Ids for MIR4509-1 Gene

Previous GeneCards Identifiers for MIR4509-1 Gene

  • GC15U901394
  • GC15M022675
  • GC15P023860
  • GC15P023945
  • GC15P023978

Summaries for MIR4509-1 Gene

Entrez Gene Summary for MIR4509-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4509-1 Gene

MIR4509-1 (MicroRNA 4509-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4509-1 Gene

Genomics for MIR4509-1 Gene

Genomic Location for MIR4509-1 Gene

Chromosome:
15
Start:
23,197,827 bp from pter
End:
23,197,920 bp from pter
Size:
94 bases
Orientation:
Plus strand

Genomic View for MIR4509-1 Gene

Genes around MIR4509-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4509-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4509-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4509-1 Gene

No data available for Regulatory Elements for MIR4509-1 Gene

Proteins for MIR4509-1 Gene

Post-translational modifications for MIR4509-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4509-1 Gene

Domains & Families for MIR4509-1 Gene

Gene Families for MIR4509-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4509-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4509-1 Gene

Function for MIR4509-1 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4509-1 Gene

Localization for MIR4509-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4509-1 Gene

Pathways & Interactions for MIR4509-1 Gene

SuperPathways for MIR4509-1 Gene

No Data Available

Interacting Proteins for MIR4509-1 Gene

Gene Ontology (GO) - Biological Process for MIR4509-1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4509-1 Gene

Drugs & Compounds for MIR4509-1 Gene

No Compound Related Data Available

Transcripts for MIR4509-1 Gene

mRNA/cDNA for MIR4509-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4509-1 Gene

No ASD Table

Relevant External Links for MIR4509-1 Gene

GeneLoc Exon Structure for
MIR4509-1
ECgene alternative splicing isoforms for
MIR4509-1

Expression for MIR4509-1 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4509-1 Gene

Orthologs for MIR4509-1 Gene

Evolution for MIR4509-1 Gene

ENSEMBL:
Gene Tree for MIR4509-1 (if available)
TreeFam:
Gene Tree for MIR4509-1 (if available)

No data available for Orthologs for MIR4509-1 Gene

Paralogs for MIR4509-1 Gene

No data available for Paralogs for MIR4509-1 Gene

Variants for MIR4509-1 Gene

Sequence variations from dbSNP and Humsavar for MIR4509-1 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs56279022 -- 23,196,307(-) CAGGC(A/C)TTTTC upstream-variant-2KB
rs57413612 -- 23,195,932(-) AAAAA(-/A)GTTTA upstream-variant-2KB
rs62010293 -- 23,196,942(-) GGAAA(A/G)ACAAC upstream-variant-2KB
rs71230786 -- 23,196,556(+) TGAAA(A/C)AAGAG upstream-variant-2KB
rs143769748 -- 23,196,507(-) GTCGC(A/C)AAATG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4509-1 Gene

Variant ID Type Subtype PubMed ID
dgv2403n100 CNV gain 25217958
dgv2404n100 CNV gain 25217958
dgv2405n100 CNV gain+loss 25217958
dgv2406n100 CNV gain 25217958
dgv2407n100 CNV gain+loss 25217958
dgv2408n100 CNV loss 25217958
dgv2491n100 CNV gain 25217958
dgv2492n100 CNV gain 25217958
dgv725e212 CNV loss 25503493
esv22824 CNV gain+loss 19812545
esv26019 CNV gain+loss 19812545
esv2674813 CNV deletion 23128226
esv2760021 CNV gain+loss 17122850
esv3892626 CNV gain+loss 25118596
nsv1036020 CNV loss 25217958
nsv1052131 CNV gain 25217958
nsv1076408 CNV duplication 25765185
nsv1132411 CNV duplication 24896259
nsv1148560 OTHER inversion 26484159
nsv1149868 CNV duplication 26484159
nsv428299 CNV loss 18775914
nsv433429 CNV gain 18776910
nsv509562 CNV insertion 20534489
nsv511042 OTHER inversion 20534489
nsv568662 CNV gain 21841781
nsv568674 CNV loss 21841781
nsv832941 CNV gain+loss 17160897
nsv9181 CNV gain+loss 18304495

Relevant External Links for MIR4509-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4509-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4509-1 Gene

Disorders for MIR4509-1 Gene

Relevant External Links for MIR4509-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4509-1

No disorders were found for MIR4509-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4509-1 Gene

Publications for MIR4509-1 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 65
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 65

Products for MIR4509-1 Gene

Sources for MIR4509-1 Gene

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