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Aliases for MIR4509-1 Gene

Subcategory (RNA class) for MIR4509-1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4509-1 Gene

  • MicroRNA 4509-1 2 3 5
  • Hsa-Mir-4509-1 3

External Ids for MIR4509-1 Gene

Previous GeneCards Identifiers for MIR4509-1 Gene

  • GC15U901394
  • GC15M022675
  • GC15P023860
  • GC15P023945

Summaries for MIR4509-1 Gene

Entrez Gene Summary for MIR4509-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4509-1 Gene

MIR4509-1 (MicroRNA 4509-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4509-1 Gene

Genomics for MIR4509-1 Gene

Regulatory Elements for MIR4509-1 Gene

Enhancers for MIR4509-1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR4509-1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4509-1 Gene

Chromosome:
15
Start:
23,197,827 bp from pter
End:
23,197,920 bp from pter
Size:
94 bases
Orientation:
Plus strand

Genomic View for MIR4509-1 Gene

Genes around MIR4509-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4509-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4509-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4509-1 Gene

Proteins for MIR4509-1 Gene

Post-translational modifications for MIR4509-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4509-1 Gene

Domains & Families for MIR4509-1 Gene

Gene Families for MIR4509-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4509-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4509-1 Gene

Function for MIR4509-1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4509-1 Gene

Localization for MIR4509-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4509-1 Gene

Pathways & Interactions for MIR4509-1 Gene

SuperPathways for MIR4509-1 Gene

No Data Available

Interacting Proteins for MIR4509-1 Gene

Gene Ontology (GO) - Biological Process for MIR4509-1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4509-1 Gene

Drugs & Compounds for MIR4509-1 Gene

No Compound Related Data Available

Transcripts for MIR4509-1 Gene

mRNA/cDNA for MIR4509-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4509-1 Gene

No ASD Table

Relevant External Links for MIR4509-1 Gene

GeneLoc Exon Structure for
MIR4509-1
ECgene alternative splicing isoforms for
MIR4509-1

Expression for MIR4509-1 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR4509-1 Gene

Orthologs for MIR4509-1 Gene

Evolution for MIR4509-1 Gene

ENSEMBL:
Gene Tree for MIR4509-1 (if available)
TreeFam:
Gene Tree for MIR4509-1 (if available)

No data available for Orthologs for MIR4509-1 Gene

Paralogs for MIR4509-1 Gene

No data available for Paralogs for MIR4509-1 Gene

Variants for MIR4509-1 Gene

Sequence variations from dbSNP and Humsavar for MIR4509-1 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs62010293 -- 23,196,942(-) GGAAA(A/G)ACAAC upstream-variant-2KB
rs71230786 -- 23,196,556(+) TGAAA(A/C)AAGAG upstream-variant-2KB
rs75806268 -- 23,197,015(+) CAAAC(A/G)TAGAA upstream-variant-2KB
rs377398510 -- 23,197,116(-) TTTTT(A/G)GCTTT upstream-variant-2KB
rs56279022 -- 23,196,307(-) CAGGC(A/C)TTTTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4509-1 Gene

Variant ID Type Subtype PubMed ID
dgv669e1 CNV Complex 17122850
nsv428296 CNV Gain+Loss 18775914
dgv93e55 CNV Gain 17911159
dgv2081n71 CNV Gain 21882294
nsv7260 OTHER Inversion 18451855
dgv679e1 CNV Complex 17122850
esv33051 CNV Gain+Loss 17666407
dgv44n16 CNV Insertion 17901297
dgv2110n71 CNV Gain 21882294
esv2751489 CNV Gain 17911159
dgv686e1 CNV Complex 17122850
dgv97e55 CNV Loss 17911159
dgv98e55 CNV Gain 17911159
esv34233 CNV Loss 17911159
essv13315 CNV CNV 17122850
dgv2200n71 CNV Gain 21882294
dgv2202n71 CNV Loss 21882294
dgv693e1 CNV Complex 17122850
dgv101e55 CNV Loss 17911159
nsv437797 CNV Loss 16327808
dgv695e1 CNV Complex 17122850
esv26683 CNV Gain+Loss 19812545
nsv469776 CNV Loss 16826518
nsv9181 CNV Gain+Loss 18304495
nsv511042 OTHER Inversion 20534489
nsv832922 CNV Gain+Loss 17160897
nsv903493 CNV Gain 21882294
nsv903494 CNV Gain 21882294
nsv433429 CNV Gain 18776910
nsv832923 CNV Gain+Loss 17160897
nsv903495 CNV Gain 21882294
nsv428299 CNV Loss 18775914
dgv712e1 CNV Complex 17122850
dgv713e1 CNV Complex 17122850
esv2674813 CNV Deletion 23128226
esv22824 CNV Gain+Loss 19812545
nsv509562 CNV Insertion 20534489
nsv832941 CNV Gain+Loss 17160897
esv26019 CNV Gain+Loss 19812545

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for MIR4509-1 Gene

Disorders for MIR4509-1 Gene

Relevant External Links for MIR4509-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4509-1

No disorders were found for MIR4509-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4509-1 Gene

Publications for MIR4509-1 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 67
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR4509-1 Gene

Sources for MIR4509-1 Gene

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