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Aliases for MIR4506 Gene

Subcategory (RNA class) for MIR4506 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4506 Gene

  • MicroRNA 4506 2 3 5
  • Hsa-Mir-4506 3

External Ids for MIR4506 Gene

Previous GeneCards Identifiers for MIR4506 Gene

  • GC14U901280
  • GC14M094416

Summaries for MIR4506 Gene

Entrez Gene Summary for MIR4506 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4506 Gene

MIR4506 (MicroRNA 4506) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4506 Gene

Genomics for MIR4506 Gene

Regulatory Elements for MIR4506 Gene

Enhancers for MIR4506 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F093944 1.1 Ensembl ENCODE 0.8 +2.6 2578 3.5 ELF3 SOX13 GTF2F1 CTCF SAP130 TEAD4 ARID4B RAD21 YY1 TEAD3 MIR4506 LOC105370632
GH14F093952 1.8 FANTOM5 Ensembl ENCODE 0.4 -14.1 -14099 19.2 HDGF PKNOX1 MLX WRNIP1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 SERPINA1 LINC00521 IFI27L2 IFI27 RPSAP4 FAM181A-AS1 ASB2 DDX24 MIR4506
GH14F093973 1.4 FANTOM5 Ensembl ENCODE 0.3 -28.1 -28144 5.9 HDGF TBP PKNOX1 TBL1XR1 WRNIP1 SIN3A YBX1 BMI1 RAD21 ZBTB40 IFI27L2 ASB2 SERPINA1 MIR4506
GH14F093940 1 Ensembl ENCODE 0.4 +6.6 6624 2.6 FEZF1 ZIC2 TEAD3 POLR2A PATZ1 FOS ZNF600 MAFK TCF7L2 MAZ LOC105370632 MIR4506
GH14F093943 0.6 ENCODE 0.4 +5.1 5061 0.1 GATAD2A NFIL3 CEBPA HLF KDM1A CEBPG LOC105370632 MIR4506
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4506 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4506 Gene

Chromosome:
14
Start:
93,948,226 bp from pter
End:
93,948,302 bp from pter
Size:
77 bases
Orientation:
Minus strand

Genomic View for MIR4506 Gene

Genes around MIR4506 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4506 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4506 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4506 Gene

Proteins for MIR4506 Gene

Post-translational modifications for MIR4506 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4506 Gene

Domains & Families for MIR4506 Gene

Gene Families for MIR4506 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4506: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4506 Gene

Function for MIR4506 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4506 Gene

Localization for MIR4506 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4506 Gene

Pathways & Interactions for MIR4506 Gene

SuperPathways for MIR4506 Gene

No Data Available

Interacting Proteins for MIR4506 Gene

Gene Ontology (GO) - Biological Process for MIR4506 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4506 Gene

Transcripts for MIR4506 Gene

mRNA/cDNA for MIR4506 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4506 Gene

No ASD Table

Relevant External Links for MIR4506 Gene

GeneLoc Exon Structure for
MIR4506
ECgene alternative splicing isoforms for
MIR4506

Expression for MIR4506 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4506 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4506 Gene:

MIR4506
genes like me logo Genes that share expression patterns with MIR4506: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4506 Gene

Orthologs for MIR4506 Gene

Evolution for MIR4506 Gene

ENSEMBL:
Gene Tree for MIR4506 (if available)
TreeFam:
Gene Tree for MIR4506 (if available)

No data available for Orthologs for MIR4506 Gene

Paralogs for MIR4506 Gene

No data available for Paralogs for MIR4506 Gene

Variants for MIR4506 Gene

Sequence variations from dbSNP and Humsavar for MIR4506 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs111779532 -- 93,949,913(+) CCCCA(C/G)TGCTC intron-variant, upstream-variant-2KB
rs112590198 -- 93,950,112(+) TGGGA(C/T)GAGCA intron-variant, upstream-variant-2KB
rs113039751 -- 93,947,886(+) CTACT(C/T)GGGAG intron-variant, downstream-variant-500B
rs113329088 -- 93,948,675(+) CACTT(A/G)TAATC intron-variant, upstream-variant-2KB
rs114293052 -- 93,948,118(+) ACATC(G/T)TGCTT intron-variant, downstream-variant-500B

Relevant External Links for MIR4506 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4506

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4506 Gene

Disorders for MIR4506 Gene

Relevant External Links for MIR4506

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4506

No disorders were found for MIR4506 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4506 Gene

Publications for MIR4506 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4506 Gene

Sources for MIR4506 Gene

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