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Aliases for MIR4506 Gene

Subcategory (RNA class) for MIR4506 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4506 Gene

  • MicroRNA 4506 2 3 5
  • Hsa-Mir-4506 3

External Ids for MIR4506 Gene

Previous GeneCards Identifiers for MIR4506 Gene

  • GC14U901280
  • GC14M094416

Summaries for MIR4506 Gene

Entrez Gene Summary for MIR4506 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4506 Gene

MIR4506 (MicroRNA 4506) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4506 Gene

Genomics for MIR4506 Gene

Regulatory Elements for MIR4506 Gene

Enhancers for MIR4506 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14G093953 2 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -11.7 -11699 13.2 HDGF PKNOX1 FOXA2 MLX WRNIP1 ZFP64 SIN3A ARID4B FEZF1 DMAP1 SERPINA1 C14orf48 UBR7 IFI27L2 IFI27 RPSAP4 FAM181A-AS1 ASB2 DDX24 MIR4506
GH14G093944 1.1 ENCODE dbSUPER 0.7 +2.6 2578 3.5 ELF3 ARID4B RAD21 YY1 SLC30A9 FOS IKZF2 MIXL1 ZNF654 JUNB MIR4506 ENSG00000258987
GH14G093966 1.4 Ensembl ENCODE dbSUPER 0.4 -19.9 -19868 3.2 PKNOX1 TBL1XR1 ZSCAN4 ARID4B BMI1 ZNF2 RAD21 ZNF143 RELB ETV6 ASB2 MIR4506
GH14G093940 1.3 Ensembl ENCODE dbSUPER 0.4 +6.6 6624 2.6 FEZF1 ZIC2 TEAD3 POLR2A EED PATZ1 FOS ZNF600 MAFK TCF7L2 ENSG00000258987 MIR4506
GH14G093970 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.3 -22.7 -22699 1.5 HDGF PKNOX1 TBL1XR1 BMI1 RAD21 RFX5 ZNF143 ZNF207 RELB ETV6 SERPINA1 ASB2 MIR4506
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4506 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4506 Gene

Chromosome:
14
Start:
93,948,226 bp from pter
End:
93,948,302 bp from pter
Size:
77 bases
Orientation:
Minus strand

Genomic View for MIR4506 Gene

Genes around MIR4506 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4506 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4506 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4506 Gene

Proteins for MIR4506 Gene

Post-translational modifications for MIR4506 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4506 Gene

Domains & Families for MIR4506 Gene

Gene Families for MIR4506 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4506: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4506 Gene

Function for MIR4506 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4506 Gene

Localization for MIR4506 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4506 Gene

Pathways & Interactions for MIR4506 Gene

SuperPathways for MIR4506 Gene

No Data Available

Interacting Proteins for MIR4506 Gene

Gene Ontology (GO) - Biological Process for MIR4506 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4506 Gene

Drugs & Compounds for MIR4506 Gene

No Compound Related Data Available

Transcripts for MIR4506 Gene

mRNA/cDNA for MIR4506 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4506 Gene

No ASD Table

Relevant External Links for MIR4506 Gene

GeneLoc Exon Structure for
MIR4506
ECgene alternative splicing isoforms for
MIR4506

Expression for MIR4506 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4506 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4506 Gene:

MIR4506
genes like me logo Genes that share expression patterns with MIR4506: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4506 Gene

Orthologs for MIR4506 Gene

Evolution for MIR4506 Gene

ENSEMBL:
Gene Tree for MIR4506 (if available)
TreeFam:
Gene Tree for MIR4506 (if available)

No data available for Orthologs for MIR4506 Gene

Paralogs for MIR4506 Gene

No data available for Paralogs for MIR4506 Gene

Variants for MIR4506 Gene

Sequence variations from dbSNP and Humsavar for MIR4506 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1001966271 -- 93,948,083(+) ATGCT(G/T)GTTTT intron-variant, downstream-variant-500B
rs1002032440 -- 93,949,561(+) GCCTC(C/T)GGCCT intron-variant, upstream-variant-2KB
rs1003077656 -- 93,949,984(+) AGGGT(A/G)GGGTG intron-variant, upstream-variant-2KB
rs1004291189 -- 93,949,669(+) CAAGA(A/G)AAATA intron-variant, upstream-variant-2KB
rs1004301064 -- 93,949,910(+) GTTCC(C/G)CACTG intron-variant, upstream-variant-2KB

Relevant External Links for MIR4506 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4506

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4506 Gene

Disorders for MIR4506 Gene

Relevant External Links for MIR4506

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4506

No disorders were found for MIR4506 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4506 Gene

Publications for MIR4506 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4506 Gene

Sources for MIR4506 Gene

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