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Aliases for MIR4505 Gene

Subcategory (RNA class) for MIR4505 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4505 Gene

  • MicroRNA 4505 2 3 5
  • Hsa-Mir-4505 3
  • Mir-4505 3

External Ids for MIR4505 Gene

Previous GeneCards Identifiers for MIR4505 Gene

  • GC14U901283
  • GC14P074226

Summaries for MIR4505 Gene

Entrez Gene Summary for MIR4505 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4505 Gene

MIR4505 (MicroRNA 4505) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4505 Gene

Genomics for MIR4505 Gene

Regulatory Elements for MIR4505 Gene

Enhancers for MIR4505 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14G073748 1.8 FANTOM5 ENCODE dbSUPER 0.7 -1.1 -1122 17.4 MLX CREB3L1 AGO1 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 ELMSAN1 PNMA1 ZNF410 LOC100506476 PTGR2 ENSG00000223300 DNAL1 ACOT1 ENSG00000258944 NT5CP2
GH14G073767 1.9 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +12.8 12793 7.9 HDGF PKNOX1 MLX ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 SLC30A9 ENSG00000258559 RBM25 PTGR2 LOC100506476 PNMA1 ENSG00000223300 ELMSAN1 LINC02274 ACOT1 ENTPD5
GH14G073775 0.8 ENCODE dbSUPER 0.4 +17.4 17436 0.4 CBX8 PKNOX1 SUZ12 CBX2 EZH2 PNMA1 PTGR2 ENSG00000223300 ELMSAN1 GC14M073765 MIR4505
GH14G073776 0.8 ENCODE dbSUPER 0.4 +17.1 17126 0.2 CBX8 PKNOX1 RNF2 SUZ12 CBX2 EZH2 PNMA1 PTGR2 ENSG00000223300 GC14M073765 MIR4505
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4505 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4505 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000070665 753 2201 HDGF HNRNPUL1 PKNOX1 MLX CREB3L1 AGO1 ARID4B SIN3A FEZF1 DMAP1

Genomic Location for MIR4505 Gene

Chromosome:
14
Start:
73,758,747 bp from pter
End:
73,758,819 bp from pter
Size:
73 bases
Orientation:
Plus strand

Genomic View for MIR4505 Gene

Genes around MIR4505 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4505 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4505 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4505 Gene

Proteins for MIR4505 Gene

Post-translational modifications for MIR4505 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4505 Gene

Domains & Families for MIR4505 Gene

Gene Families for MIR4505 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4505: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4505 Gene

Function for MIR4505 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4505 Gene

Localization for MIR4505 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4505 Gene

Pathways & Interactions for MIR4505 Gene

SuperPathways for MIR4505 Gene

No Data Available

Interacting Proteins for MIR4505 Gene

Gene Ontology (GO) - Biological Process for MIR4505 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4505 Gene

Drugs & Compounds for MIR4505 Gene

No Compound Related Data Available

Transcripts for MIR4505 Gene

mRNA/cDNA for MIR4505 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4505 Gene

No ASD Table

Relevant External Links for MIR4505 Gene

GeneLoc Exon Structure for
MIR4505
ECgene alternative splicing isoforms for
MIR4505

Expression for MIR4505 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4505 Gene:

MIR4505
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4505 Gene

Orthologs for MIR4505 Gene

Evolution for MIR4505 Gene

ENSEMBL:
Gene Tree for MIR4505 (if available)
TreeFam:
Gene Tree for MIR4505 (if available)

No data available for Orthologs for MIR4505 Gene

Paralogs for MIR4505 Gene

No data available for Paralogs for MIR4505 Gene

Variants for MIR4505 Gene

Sequence variations from dbSNP and Humsavar for MIR4505 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1000221769 -- 73,759,302(+) CGCGC(C/T)TTCCG intron-variant, downstream-variant-500B
rs1003279188 -- 73,759,037(+) CGAGG(C/T)ACCGC intron-variant, downstream-variant-500B
rs1004339924 -- 73,758,843(+) CCCAG(A/G)GCACA intron-variant, downstream-variant-500B
rs1006685828 -- 73,756,955(+) ATGGA(A/G)ATCTT intron-variant, upstream-variant-2KB
rs1007229066 -- 73,758,430(+) CCTTC(A/G)GTCTC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4505 Gene

Variant ID Type Subtype PubMed ID
nsv1035460 CNV gain 25217958
nsv1053281 CNV gain 25217958

Relevant External Links for MIR4505 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4505

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4505 Gene

Disorders for MIR4505 Gene

Relevant External Links for MIR4505

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4505

No disorders were found for MIR4505 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4505 Gene

Publications for MIR4505 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4505 Gene

Sources for MIR4505 Gene

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