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Aliases for MIR4503 Gene

Subcategory (RNA class) for MIR4503 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4503 Gene

  • MicroRNA 4503 2 3 5
  • Hsa-Mir-4503 3

External Ids for MIR4503 Gene

Previous GeneCards Identifiers for MIR4503 Gene

  • GC14U901281
  • GC14M037423

Summaries for MIR4503 Gene

Entrez Gene Summary for MIR4503 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4503 Gene

MIR4503 (MicroRNA 4503) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4503 Gene

Genomics for MIR4503 Gene

Regulatory Elements for MIR4503 Gene

Enhancers for MIR4503 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14G036952 0.7 ENCODE 0.7 -0.7 -690 1.3 FOXA2 JUN EP300 RAD21 FOXA1 CTBP1 JUND GATA3 MAFF STAT3 PAX9 MIR4503 GC14P036975
GH14G036944 0.9 ENCODE 0.4 +7.6 7567 0.3 ELF3 FOXA2 DMAP1 ZSCAN9 RAD21 RARA GATA4 SMARCC2 RCOR1 FOS MIR4503 ENSG00000258601
GH14G036942 0.7 ENCODE 0.4 +10.0 10011 0.1 CTCF HBP1 RAD21 GATA3 ZNF143 SMC3 NR2F6 HOMEZ MIXL1 THAP11 MIR4503 ENSG00000258601
GH14G036973 0.7 ENCODE 0.3 -21.8 -21769 1.0 STAT1 NRF1 JUN FEZF1 FOSL1 ARID1B JUND ATF3 SMARCA4 STAT3 GC14P036975 MIR4503
GH14G036848 0.7 FANTOM5 0.1 +104.1 104073 0.4 HDAC1 TBP PKNOX1 ZNF837 GFI1B CEBPB YBX1 CEBPG IRF9 ZSCAN21 MIPOL1 NKX2-8 SLC25A21 ENSG00000258601 MIR4503
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4503 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4503 Gene

Chromosome:
14
Start:
36,952,309 bp from pter
End:
36,952,391 bp from pter
Size:
83 bases
Orientation:
Minus strand

Genomic View for MIR4503 Gene

Genes around MIR4503 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4503 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4503 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4503 Gene

Proteins for MIR4503 Gene

Post-translational modifications for MIR4503 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4503 Gene

Domains & Families for MIR4503 Gene

Gene Families for MIR4503 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4503: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4503 Gene

Function for MIR4503 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4503 Gene

Localization for MIR4503 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4503 Gene

Pathways & Interactions for MIR4503 Gene

SuperPathways for MIR4503 Gene

No Data Available

Interacting Proteins for MIR4503 Gene

Gene Ontology (GO) - Biological Process for MIR4503 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4503 Gene

Drugs & Compounds for MIR4503 Gene

No Compound Related Data Available

Transcripts for MIR4503 Gene

mRNA/cDNA for MIR4503 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4503 Gene

No ASD Table

Relevant External Links for MIR4503 Gene

GeneLoc Exon Structure for
MIR4503
ECgene alternative splicing isoforms for
MIR4503

Expression for MIR4503 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4503 Gene:

MIR4503
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4503 Gene

Orthologs for MIR4503 Gene

Evolution for MIR4503 Gene

ENSEMBL:
Gene Tree for MIR4503 (if available)
TreeFam:
Gene Tree for MIR4503 (if available)

No data available for Orthologs for MIR4503 Gene

Paralogs for MIR4503 Gene

No data available for Paralogs for MIR4503 Gene

Variants for MIR4503 Gene

Sequence variations from dbSNP and Humsavar for MIR4503 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1000863825 -- 36,953,137(+) TTAAC(A/G)ATAAC intron-variant, upstream-variant-2KB
rs1000947724 -- 36,953,179(+) ATGTG(A/C)TTGAA intron-variant, upstream-variant-2KB
rs1001750875 -- 36,954,183(+) CCCCA(A/G)TAAAA intron-variant, upstream-variant-2KB
rs1002443428 -- 36,953,800(+) ACTTA(A/C)CACAT intron-variant, upstream-variant-2KB
rs1002909629 -- 36,953,524(+) CACAA(A/C/T)GTAGG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4503 Gene

Variant ID Type Subtype PubMed ID
esv3634080 CNV loss 21293372

Relevant External Links for MIR4503 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4503

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4503 Gene

Disorders for MIR4503 Gene

Relevant External Links for MIR4503

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4503

No disorders were found for MIR4503 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4503 Gene

Publications for MIR4503 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4503 Gene

Sources for MIR4503 Gene

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