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Aliases for MIR4502 Gene

Subcategory (RNA class) for MIR4502 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4502 Gene

  • MicroRNA 4502 2 3 5
  • Hsa-Mir-4502 3

External Ids for MIR4502 Gene

Previous GeneCards Identifiers for MIR4502 Gene

  • GC13U900865
  • GC13P115041

Summaries for MIR4502 Gene

Entrez Gene Summary for MIR4502 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4502 Gene

MIR4502 (MicroRNA 4502) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4502 Gene

Genomics for MIR4502 Gene

Regulatory Elements for MIR4502 Gene

Enhancers for MIR4502 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH13F114262 0.7 Ensembl ENCODE 0.4 -9.4 -9404 4.1 PAF1 IKZF1 CDC16 CHAMP1 MIR4502 MIR548AR
GH13F114267 0.6 Ensembl ENCODE 0.4 -5.2 -5209 2.0 JUNB MIR4502 MIR548AR
GH13F114259 0.5 ENCODE 0.4 -13.0 -13015 2.4 CTCF ZNF341 ZIC2 CDC16 UPF3A CHAMP1 RASA3 MIR4502 MIR548AR
GH13F114249 0.4 ENCODE 0.3 -24.6 -24608 0.2 CTCF ZBTB33 MIR548AR MIR4502
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4502 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4502 Gene

Chromosome:
13
Start:
114,273,828 bp from pter
End:
114,273,908 bp from pter
Size:
81 bases
Orientation:
Plus strand

Genomic View for MIR4502 Gene

Genes around MIR4502 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4502 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4502 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4502 Gene

Proteins for MIR4502 Gene

Post-translational modifications for MIR4502 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4502 Gene

Domains & Families for MIR4502 Gene

Gene Families for MIR4502 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4502: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4502 Gene

Function for MIR4502 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4502 Gene

Localization for MIR4502 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4502 Gene

Pathways & Interactions for MIR4502 Gene

SuperPathways for MIR4502 Gene

No Data Available

Interacting Proteins for MIR4502 Gene

Gene Ontology (GO) - Biological Process for MIR4502 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4502 Gene

Transcripts for MIR4502 Gene

mRNA/cDNA for MIR4502 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4502 Gene

No ASD Table

Relevant External Links for MIR4502 Gene

GeneLoc Exon Structure for
MIR4502
ECgene alternative splicing isoforms for
MIR4502

Expression for MIR4502 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4502 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4502 Gene:

MIR4502
genes like me logo Genes that share expression patterns with MIR4502: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4502 Gene

Orthologs for MIR4502 Gene

Evolution for MIR4502 Gene

ENSEMBL:
Gene Tree for MIR4502 (if available)
TreeFam:
Gene Tree for MIR4502 (if available)

No data available for Orthologs for MIR4502 Gene

Paralogs for MIR4502 Gene

No data available for Paralogs for MIR4502 Gene

Variants for MIR4502 Gene

Sequence variations from dbSNP and Humsavar for MIR4502 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs112063020 -- 114,273,077(+) TTGGA(-/GTTT)GTTTG intron-variant, nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB
rs114368937 -- 114,273,959(+) TTGAT(G/T)GACTC intron-variant, downstream-variant-500B
rs11554301 -- 114,272,534(-) GTCAC(A/G)TTAGG intron-variant, nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB, utr-variant-3-prime
rs12583365 -- 114,271,891(+) GCAAC(C/T)GCATG intron-variant, nc-transcript-variant, upstream-variant-2KB
rs12854357 -- 114,273,851(+) atctt(C/T)ttgct intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4502 Gene

Variant ID Type Subtype PubMed ID
nsv563534 CNV gain 21841781
nsv563533 CNV loss 21841781
nsv563532 CNV gain 21841781
nsv456143 CNV gain 19166990
nsv1050622 CNV gain 25217958
nsv1043111 CNV gain 25217958
esv3633644 CNV gain 21293372
esv3633643 CNV gain 21293372
esv3633642 CNV gain 21293372
esv3582871 CNV gain 25503493
esv25715 CNV gain+loss 19812545
dgv1748n100 CNV gain 25217958
dgv1747n100 CNV gain 25217958
dgv1746n100 CNV gain 25217958
dgv1745n100 CNV gain 25217958

Relevant External Links for MIR4502 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4502

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4502 Gene

Disorders for MIR4502 Gene

Relevant External Links for MIR4502

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4502

No disorders were found for MIR4502 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4502 Gene

Publications for MIR4502 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4502 Gene

Sources for MIR4502 Gene

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