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Aliases for MIR4500 Gene

Subcategory (RNA class) for MIR4500 Gene


Quality Score for this RNA gene is


Aliases for MIR4500 Gene

  • MicroRNA 4500 2 3 5
  • Hsa-Mir-4500 3

External Ids for MIR4500 Gene

Previous GeneCards Identifiers for MIR4500 Gene

  • GC13U900859
  • GC13M088271

Summaries for MIR4500 Gene

Entrez Gene Summary for MIR4500 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4500 Gene

MIR4500 (MicroRNA 4500) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4500 Gene

Genomics for MIR4500 Gene

Regulatory Elements for MIR4500 Gene

Enhancers for MIR4500 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH13F087670 0.2 ENCODE 0.2 -52.5 -52492 1.2 TBP PKNOX1 SIN3A ZNF48 RAD21 RFX5 YY1 GLIS2 ELK1 ZNF366 SLITRK5 MIR4500
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4500 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4500 Gene

87,618,665 bp from pter
87,618,740 bp from pter
76 bases
Minus strand

Genomic View for MIR4500 Gene

Genes around MIR4500 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4500 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4500 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4500 Gene

ORGUL Member Location for MIR4500 Gene

ORGUL Member Location for MIR4500 gene

Proteins for MIR4500 Gene

Post-translational modifications for MIR4500 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4500 Gene

Domains & Families for MIR4500 Gene

Gene Families for MIR4500 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4500: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4500 Gene

Function for MIR4500 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4500 Gene

Localization for MIR4500 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4500 Gene

Pathways & Interactions for MIR4500 Gene

SuperPathways for MIR4500 Gene

No Data Available

Interacting Proteins for MIR4500 Gene

Gene Ontology (GO) - Biological Process for MIR4500 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4500 Gene

Transcripts for MIR4500 Gene

mRNA/cDNA for MIR4500 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4500 Gene

No ASD Table

Relevant External Links for MIR4500 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4500 Gene

mRNA expression in normal human tissues for MIR4500 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4500 Gene:

genes like me logo Genes that share expression patterns with MIR4500: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4500 Gene

Orthologs for MIR4500 Gene

Evolution for MIR4500 Gene

Gene Tree for MIR4500 (if available)
Gene Tree for MIR4500 (if available)

No data available for Orthologs for MIR4500 Gene

Paralogs for MIR4500 Gene

No data available for Paralogs for MIR4500 Gene

Variants for MIR4500 Gene

Sequence variations from dbSNP and Humsavar for MIR4500 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs113112831 -- 87,620,540(+) TGTGT(-/GT)GTGTG intron-variant, upstream-variant-2KB
rs114793992 -- 87,619,934(+) TATAA(C/T)TTACT intron-variant, upstream-variant-2KB
rs116574634 -- 87,620,263(+) AGCTC(C/T)GCAAA intron-variant, upstream-variant-2KB
rs138505635 -- 87,620,217(+) TAAGG(C/G)AGACA intron-variant, upstream-variant-2KB
rs138741629 -- 87,620,533(+) TGTGA(-/GTGT)GTGTG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4500 Gene

Variant ID Type Subtype PubMed ID
dgv1725n100 CNV loss 25217958
esv2759956 CNV loss 17122850
esv3580797 CNV loss 25503493
nsv1044071 CNV loss 25217958
nsv519480 CNV loss 19592680
nsv562629 CNV gain 21841781
nsv562630 CNV loss 21841781

Relevant External Links for MIR4500 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4500 Gene

Disorders for MIR4500 Gene

Relevant External Links for MIR4500

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4500 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4500 Gene

Publications for MIR4500 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4500 Gene

Sources for MIR4500 Gene

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