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Aliases for MIR4494 Gene

Subcategory (RNA class) for MIR4494 Gene


Quality Score for this RNA gene is


Aliases for MIR4494 Gene

  • MicroRNA 4494 2 3
  • Hsa-Mir-4494 3

External Ids for MIR4494 Gene

Previous GeneCards Identifiers for MIR4494 Gene

  • GC12U901596
  • GC12M047759

Summaries for MIR4494 Gene

Entrez Gene Summary for MIR4494 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4494 Gene

MIR4494 (MicroRNA 4494) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4494 Gene

Genomics for MIR4494 Gene

Genomic Location for MIR4494 Gene

47,364,186 bp from pter
47,364,269 bp from pter
84 bases
Minus strand

Genomic View for MIR4494 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4494 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4494 Gene

No data available for Regulatory Elements for MIR4494 Gene

Proteins for MIR4494 Gene

Post-translational modifications for MIR4494 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4494 Gene

Domains for MIR4494 Gene

Gene Families for MIR4494 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4494: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4494 Gene

Function for MIR4494 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4494 Gene

Localization for MIR4494 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4494 Gene

Pathways for MIR4494 Gene

SuperPathways for MIR4494 Gene

No Data Available

Interacting Proteins for MIR4494 Gene

Gene Ontology (GO) - Biological Process for MIR4494 Gene


No data available for Pathways by source for MIR4494 Gene

Transcripts for MIR4494 Gene

mRNA/cDNA for MIR4494 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4494 Gene

No ASD Table

Relevant External Links for MIR4494 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4494 Gene

mRNA expression in normal human tissues for MIR4494 Gene

genes like me logo Genes that share expressions with MIR4494: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR4494 Gene

Orthologs for MIR4494 Gene

Evolution for MIR4494 Gene

Gene Tree for MIR4494 (if available)
Gene Tree for MIR4494 (if available)

No data available for Orthologs for MIR4494 Gene

Paralogs for MIR4494 Gene

No data available for Paralogs for MIR4494 Gene

Variants for MIR4494 Gene

Sequence variations from dbSNP and Humsavar for MIR4494 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs73299471 -- 47,366,051(+) ACCAA(G/T)ATGAC upstream-variant-2KB
rs73299470 -- 47,365,274(+) GTAAT(A/G)ATAGT upstream-variant-2KB
rs61929785 -- 47,364,626(+) AAATT(A/T)AAATG upstream-variant-2KB
rs59823822 -- 47,364,606(+) AAAAA(-/A)TTTAA upstream-variant-2KB
rs34692456 -- 47,366,263(+) TAAAA(A/T)CAGGC upstream-variant-2KB

Relevant External Links for MIR4494 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MIR4494 Gene

Disorders for MIR4494 Gene

No disorders were found for MIR4494 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR4494 Gene

Publications for MIR4494 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3

Products for MIR4494 Gene

Sources for MIR4494 Gene

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