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Aliases for MIR4493 Gene

Subcategory (RNA class) for MIR4493 Gene


Quality Score for this RNA gene is


Aliases for MIR4493 Gene

  • MicroRNA 4493 2 3 5
  • Hsa-Mir-4493 3

External Ids for MIR4493 Gene

Previous GeneCards Identifiers for MIR4493 Gene

  • GC11U901854
  • GC11M123254

Summaries for MIR4493 Gene

Entrez Gene Summary for MIR4493 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4493 Gene

MIR4493 (MicroRNA 4493) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4493 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4493 Gene

Genomics for MIR4493 Gene

Regulatory Elements for MIR4493 Gene

Enhancers for MIR4493 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H123381 0.8 ENCODE 0.7 -0.3 -301 1.6 HDGF MAX CEBPG BMI1 EBF1 BATF RELA EED ZNF143 ATF7 MIR4493 GC11P123388
GH11H123377 0.5 ENCODE 0.7 +3.0 2957 1.6 SCRT1 SCRT2 TCF7L2 MIR4493 GC11M123369
GH11H123373 0.5 ENCODE 0.4 +6.9 6938 1.3 POLR2A JUNB RUNX3 GC11M123369 MIR4493
GH11H123386 0.2 ENCODE 0.4 -5.6 -5610 1.1 GC11P123388 MIR4493
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4493 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4493 Gene

Genomic Locations for MIR4493 Gene
73 bases
Minus strand

Genomic View for MIR4493 Gene

Genes around MIR4493 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4493 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4493 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4493 Gene

Proteins for MIR4493 Gene

Post-translational modifications for MIR4493 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4493 Gene

Domains & Families for MIR4493 Gene

Gene Families for MIR4493 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4493: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4493 Gene

Function for MIR4493 Gene

Phenotypes From GWAS Catalog for MIR4493 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4493 Gene

Localization for MIR4493 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4493 Gene

Pathways & Interactions for MIR4493 Gene

SuperPathways for MIR4493 Gene

No Data Available

Interacting Proteins for MIR4493 Gene

Gene Ontology (GO) - Biological Process for MIR4493 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4493 Gene

Drugs & Compounds for MIR4493 Gene

No Compound Related Data Available

Transcripts for MIR4493 Gene

mRNA/cDNA for MIR4493 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4493 Gene

No ASD Table

Relevant External Links for MIR4493 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4493 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4493 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4493 Gene

Orthologs for MIR4493 Gene

Evolution for MIR4493 Gene

Gene Tree for MIR4493 (if available)
Gene Tree for MIR4493 (if available)

No data available for Orthologs for MIR4493 Gene

Paralogs for MIR4493 Gene

No data available for Paralogs for MIR4493 Gene

Variants for MIR4493 Gene

Sequence variations from dbSNP and Humsavar for MIR4493 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1003337517 -- 123,382,881(+) GGGAG(A/G)AGCTG intron-variant, upstream-variant-2KB
rs1006176282 -- 123,381,492(+) TCACC(A/G)GAAGG intron-variant, nc-transcript-variant
rs1007444432 -- 123,381,689(+) CACTG(A/G)ATGCT intron-variant, upstream-variant-2KB
rs1007518522 -- 123,383,270(+) GTGGT(A/G)GGGAA intron-variant, upstream-variant-2KB
rs1011453251 -- 123,382,374(+) ACTTG(-/T)TTTTT intron-variant, upstream-variant-2KB

Relevant External Links for MIR4493 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4493 Gene

Disorders for MIR4493 Gene

Relevant External Links for MIR4493

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4493 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4493 Gene

Publications for MIR4493 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4493 Gene

Sources for MIR4493 Gene

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