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Aliases for MIR4492 Gene

Subcategory (RNA class) for MIR4492 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4492 Gene

  • MicroRNA 4492 2 3 5
  • Hsa-Mir-4492 3
  • Mir-4492 3

External Ids for MIR4492 Gene

Previous GeneCards Identifiers for MIR4492 Gene

  • GC11U901865
  • GC11P118783

Summaries for MIR4492 Gene

Entrez Gene Summary for MIR4492 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4492 Gene

MIR4492 (MicroRNA 4492) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4492 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4492 Gene

Genomics for MIR4492 Gene

GeneHancer (GH) Regulatory Elements for MIR4492 Gene

Promoters and enhancers for MIR4492 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I118906 Promoter/Enhancer 2.9 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.4 +8.1 8085 24.6 CLOCK MLX ZFP64 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 BCL9L DPAGT1 UBE4A ENSG00000254909 RPL23AP64 ARCN1 ENSG00000254428 RNF26 CCDC84 KMT2A
GH11I118898 Enhancer 0.4 ENCODE dbSUPER 0.4 -12.6 -12552 0 GC11P118898 MIR4492 BCL9L
GH11I118897 Enhancer 0.4 ENCODE dbSUPER 0.4 -12.8 -12781 0.2 GC11P118898 MIR4492 BCL9L
GH11I118899 Enhancer 0.4 dbSUPER 0.4 -10.6 -10616 1.3 ZNF512B ZBTB33 GC11P118898 MIR4492 BCL9L
GH11I118903 Enhancer 0.2 dbSUPER 0.4 -7.0 -7020 1.2 UPK2 ENSG00000222529 FOXR1 ENSG00000255121 CCDC84 HMBS H2AFX C2CD2L DPAGT1 GC11P118898
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4492 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4492 Gene

Genomic Locations for MIR4492 Gene
chr11:118,910,708-118,910,787
(GRCh38/hg38)
Size:
80 bases
Orientation:
Plus strand
chr11:118,781,417-118,781,496
(GRCh37/hg19)

Genomic View for MIR4492 Gene

Genes around MIR4492 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4492 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4492 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4492 Gene

Proteins for MIR4492 Gene

Post-translational modifications for MIR4492 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4492 Gene

Domains & Families for MIR4492 Gene

Gene Families for MIR4492 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4492: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4492 Gene

Function for MIR4492 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4492 Gene

Localization for MIR4492 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4492 Gene

Pathways & Interactions for MIR4492 Gene

SuperPathways for MIR4492 Gene

No Data Available

Interacting Proteins for MIR4492 Gene

Gene Ontology (GO) - Biological Process for MIR4492 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4492 Gene

Drugs & Compounds for MIR4492 Gene

No Compound Related Data Available

Transcripts for MIR4492 Gene

mRNA/cDNA for MIR4492 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4492 Gene

No ASD Table

Relevant External Links for MIR4492 Gene

GeneLoc Exon Structure for
MIR4492
ECgene alternative splicing isoforms for
MIR4492

Expression for MIR4492 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4492 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4492 Gene:

MIR4492
genes like me logo Genes that share expression patterns with MIR4492: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4492 Gene

Orthologs for MIR4492 Gene

Evolution for MIR4492 Gene

ENSEMBL:
Gene Tree for MIR4492 (if available)
TreeFam:
Gene Tree for MIR4492 (if available)

No data available for Orthologs for MIR4492 Gene

Paralogs for MIR4492 Gene

No data available for Paralogs for MIR4492 Gene

Variants for MIR4492 Gene

Sequence variations from dbSNP and Humsavar for MIR4492 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000607410 -- 118,911,250(+) G/C downstream_transcript_variant
rs1002664513 -- 118,909,149(+) T/A/C upstream_transcript_variant
rs1002912030 -- 118,910,067(+) A/G upstream_transcript_variant
rs1003375279 -- 118,910,382(+) C/T upstream_transcript_variant
rs1003842069 -- 118,909,414(+) C/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4492 Gene

Variant ID Type Subtype PubMed ID
nsv952743 CNV deletion 24416366

Additional Variant Information for MIR4492 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4492

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4492 Gene

Disorders for MIR4492 Gene

Additional Disease Information for MIR4492

No disorders were found for MIR4492 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4492 Gene

Publications for MIR4492 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4492 Gene

Sources for MIR4492 Gene

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