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Aliases for MIR4490 Gene

Subcategory (RNA class) for MIR4490 Gene


Quality Score for this RNA gene is


Aliases for MIR4490 Gene

  • MicroRNA 4490 2 3 5
  • Hsa-Mir-4490 3

External Ids for MIR4490 Gene

Previous GeneCards Identifiers for MIR4490 Gene

  • GC11U901883
  • GC11M090290

Summaries for MIR4490 Gene

Entrez Gene Summary for MIR4490 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4490 Gene

MIR4490 (MicroRNA 4490) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4490 Gene

Genomics for MIR4490 Gene

Genomic Location for MIR4490 Gene

90,555,774 bp from pter
90,555,857 bp from pter
84 bases
Minus strand

Genomic View for MIR4490 Gene

Genes around MIR4490 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4490 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4490 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4490 Gene

No data available for Regulatory Elements for MIR4490 Gene

Proteins for MIR4490 Gene

Post-translational modifications for MIR4490 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4490 Gene

Domains & Families for MIR4490 Gene

Gene Families for MIR4490 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4490: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4490 Gene

Function for MIR4490 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4490 Gene

Localization for MIR4490 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4490 Gene

Pathways & Interactions for MIR4490 Gene

SuperPathways for MIR4490 Gene

No Data Available

Interacting Proteins for MIR4490 Gene

Gene Ontology (GO) - Biological Process for MIR4490 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4490 Gene

Transcripts for MIR4490 Gene

mRNA/cDNA for MIR4490 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4490 Gene

No ASD Table

Relevant External Links for MIR4490 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4490 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4490 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4490 Gene

Orthologs for MIR4490 Gene

Evolution for MIR4490 Gene

Gene Tree for MIR4490 (if available)
Gene Tree for MIR4490 (if available)

No data available for Orthologs for MIR4490 Gene

Paralogs for MIR4490 Gene

No data available for Paralogs for MIR4490 Gene

Variants for MIR4490 Gene

Sequence variations from dbSNP and Humsavar for MIR4490 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs10765350 -- 90,557,341(+) ATACA(A/G)GTTTT intron-variant, upstream-variant-2KB
rs11019089 -- 90,555,549(+) atagg(G/T)tttaa intron-variant, downstream-variant-500B
rs112937431 -- 90,555,804(+) TTACC(A/G)GAGAC intron-variant, nc-transcript-variant
rs115305806 -- 90,557,746(+) GACCC(A/G)GGACC intron-variant, upstream-variant-2KB
rs138406907 -- 90,556,980(+) GCTAA(A/G)TGCTA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4490 Gene

Variant ID Type Subtype PubMed ID
esv3579993 CNV gain 25503493
esv3627209 CNV loss 21293372
esv3892062 CNV loss 25118596
nsv1053196 CNV loss 25217958
nsv1048624 CNV loss 25217958
nsv1039065 CNV gain 25217958
esv3892063 CNV loss 25118596

Relevant External Links for MIR4490 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4490 Gene

Disorders for MIR4490 Gene

Relevant External Links for MIR4490

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4490 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4490 Gene

Publications for MIR4490 Gene

  1. A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus. (PMID: 25130324) Cai D.C. … Hagoort P. (Genes Brain Behav. 2014) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4490 Gene

Sources for MIR4490 Gene

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