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Aliases for MIR4488 Gene

Subcategory (RNA class) for MIR4488 Gene


Quality Score for this RNA gene is


Aliases for MIR4488 Gene

  • MicroRNA 4488 2 3 5
  • Hsa-Mir-4488 3
  • Mir-4488 3

External Ids for MIR4488 Gene

Previous GeneCards Identifiers for MIR4488 Gene

  • GC11U901857
  • GC11P061280

Summaries for MIR4488 Gene

Entrez Gene Summary for MIR4488 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4488 Gene

MIR4488 (MicroRNA 4488) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4488 Gene

Genomics for MIR4488 Gene

Regulatory Elements for MIR4488 Gene

Enhancers for MIR4488 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F061498 0.5 FANTOM5 0.4 -9.6 -9591 0.3 HDAC1 TBP TAL1 CDC5L ZBTB40 POLR2A NR2F6 ETV6 CREM BCLAF1 TMEM138 DDB1 TKFC LRRC10B LOC105369329 MIR4488
GH11F061499 0.2 ENCODE 0.4 -8.3 -8286 0.7 SOX13 ESRRA TFAP4 CBX3 SAP130 MLX ZNF48 YY1 RARA GATA2 DDB1 TKFC LOC105369329 MIR4488
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4488 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4488 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001768983 604 1201 CREB3L1 ARID4B ZNF48 ZNF2 GLIS2 SP3 MXD4 ZNF592 KAT8 ZNF610

Genomic Location for MIR4488 Gene

61,508,596 bp from pter
61,508,657 bp from pter
62 bases
Plus strand

Genomic View for MIR4488 Gene

Genes around MIR4488 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4488 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4488 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4488 Gene

Proteins for MIR4488 Gene

Post-translational modifications for MIR4488 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4488 Gene

Domains & Families for MIR4488 Gene

Gene Families for MIR4488 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4488: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4488 Gene

Function for MIR4488 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4488 Gene

Localization for MIR4488 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4488 Gene

Pathways & Interactions for MIR4488 Gene

SuperPathways for MIR4488 Gene

No Data Available

Interacting Proteins for MIR4488 Gene

Gene Ontology (GO) - Biological Process for MIR4488 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4488 Gene

Transcripts for MIR4488 Gene

mRNA/cDNA for MIR4488 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4488 Gene

No ASD Table

Relevant External Links for MIR4488 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4488 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4488 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4488 Gene

Orthologs for MIR4488 Gene

Evolution for MIR4488 Gene

Gene Tree for MIR4488 (if available)
Gene Tree for MIR4488 (if available)

No data available for Orthologs for MIR4488 Gene

Paralogs for MIR4488 Gene

No data available for Paralogs for MIR4488 Gene

Variants for MIR4488 Gene

Sequence variations from dbSNP and Humsavar for MIR4488 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs10792315 -- 61,507,318(+) CTTAC(G/T)TTCCA upstream-variant-2KB
rs11230726 -- 61,507,632(+) TTATA(A/G)TGCTG upstream-variant-2KB
rs11230727 -- 61,507,706(+) AGTGA(A/T)CCTTG upstream-variant-2KB
rs113188069 -- 61,508,840(+) TCCTC(C/G)CGGCC downstream-variant-500B, utr-variant-5-prime
rs11824439 -- 61,508,382(+) ATGGC(C/T)CGCAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4488 Gene

Variant ID Type Subtype PubMed ID
dgv1962n54 CNV loss 21841781
nsv1070462 CNV deletion 25765185
nsv468582 CNV loss 19166990
nsv555167 CNV loss 21841781
nsv555168 CNV loss 21841781
nsv825938 CNV gain 20364138
nsv832178 CNV gain+loss 17160897

Relevant External Links for MIR4488 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4488 Gene

Disorders for MIR4488 Gene

Relevant External Links for MIR4488

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4488 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4488 Gene

Publications for MIR4488 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4488 Gene

Sources for MIR4488 Gene

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