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Aliases for MIR4487 Gene

Subcategory (RNA class) for MIR4487 Gene


Quality Score for this RNA gene is


Aliases for MIR4487 Gene

  • MicroRNA 4487 2 3 5
  • Hsa-Mir-4487 3
  • Mir-4487 3

External Ids for MIR4487 Gene

Previous GeneCards Identifiers for MIR4487 Gene

  • GC11U901878

Summaries for MIR4487 Gene

Entrez Gene Summary for MIR4487 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4487 Gene

MIR4487 (MicroRNA 4487) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4487 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4487 Gene

Genomics for MIR4487 Gene

Regulatory Elements for MIR4487 Gene

Enhancers for MIR4487 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H047399 1.6 FANTOM5 ENCODE dbSUPER 0.7 -0.2 -210 2.5 HDGF PKNOX1 ZNF2 TCF12 GLIS2 ELK1 RUNX3 REST SMARCA4 GLIS1 SPI1 PSMC3 FNBP4 ENSG00000255197 MADD C11orf49 CELF1 MIR4487
GH11H047397 0.5 dbSUPER 0.7 -2.5 -2530 1.3 GLIS1 ZBTB33 MLLT1 C1QTNF4 PSMC3 ENSG00000255197 MIR4487 SPI1
GH11H047398 0.5 dbSUPER 0.7 -3.6 -3607 0.6 BCOR ZMYM3 KDM1A C1QTNF4 ENSG00000255197 SPI1 MIR4487
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4487 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4487 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000039677 -770 801 HDGF PTBP1 TBL1XR1 ZNF2 ZEB1 TCF12 ELK1 EGR1 RCOR1 RUNX3

Genomic Locations for MIR4487 Gene

Genomic Locations for MIR4487 Gene
73 bases
Plus strand

Genomic View for MIR4487 Gene

Genes around MIR4487 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4487 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4487 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4487 Gene

Proteins for MIR4487 Gene

Post-translational modifications for MIR4487 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4487 Gene

Domains & Families for MIR4487 Gene

Gene Families for MIR4487 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4487: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4487 Gene

Function for MIR4487 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4487 Gene

Localization for MIR4487 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4487 Gene

Pathways & Interactions for MIR4487 Gene

SuperPathways for MIR4487 Gene

No Data Available

Interacting Proteins for MIR4487 Gene

Gene Ontology (GO) - Biological Process for MIR4487 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4487 Gene

Drugs & Compounds for MIR4487 Gene

No Compound Related Data Available

Transcripts for MIR4487 Gene

mRNA/cDNA for MIR4487 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4487 Gene

No ASD Table

Relevant External Links for MIR4487 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4487 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4487 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4487 Gene

Orthologs for MIR4487 Gene

Evolution for MIR4487 Gene

Gene Tree for MIR4487 (if available)
Gene Tree for MIR4487 (if available)

No data available for Orthologs for MIR4487 Gene

Paralogs for MIR4487 Gene

No data available for Paralogs for MIR4487 Gene

Variants for MIR4487 Gene

Sequence variations from dbSNP and Humsavar for MIR4487 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1002200556 -- 47,400,658(+) CAGGT(-/GTGG)GGGGG upstream-variant-2KB
rs1002777002 -- 47,399,284(+) ATCCA(C/G)CCACC upstream-variant-2KB
rs1003371674 -- 47,400,415(+) ACGGG(A/C/G/T)GGGGG upstream-variant-2KB
rs1003402702 -- 47,400,617(+) ACCTC(C/G/T)CCCCA upstream-variant-2KB
rs1004583171 -- 47,400,674(+) AGAGA(A/G)AAGCG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4487 Gene

Variant ID Type Subtype PubMed ID
nsv832141 CNV loss 17160897
nsv825871 CNV gain 20364138
nsv554210 CNV loss 21841781
nsv1138018 CNV deletion 24896259
esv2744437 CNV deletion 23290073

Relevant External Links for MIR4487 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4487 Gene

Disorders for MIR4487 Gene

Relevant External Links for MIR4487

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4487 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4487 Gene

Publications for MIR4487 Gene

  1. Identification of ULK1 as a novel biomarker involved in miR-4487 and miR-595 regulation in neuroblastoma SH-SY5Y cell autophagy. (PMID: 26183158) Chen Y … Liu B (Scientific reports 2015) 3 60
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  3. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 60
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4487 Gene

Sources for MIR4487 Gene

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