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Aliases for MIR4486 Gene

Subcategory (RNA class) for MIR4486 Gene


Quality Score for this RNA gene is


Aliases for MIR4486 Gene

  • MicroRNA 4486 2 3 5
  • Hsa-Mir-4486 3

External Ids for MIR4486 Gene

Previous GeneCards Identifiers for MIR4486 Gene

  • GC11U901868
  • GC11P019599

Summaries for MIR4486 Gene

Entrez Gene Summary for MIR4486 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4486 Gene

MIR4486 (MicroRNA 4486) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4486 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4486 Gene

Genomics for MIR4486 Gene

Regulatory Elements for MIR4486 Gene

Enhancers for MIR4486 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H019576 1.3 FANTOM5 Ensembl ENCODE dbSUPER 0.7 +3.0 2996 3.2 JUND POLR2A NR2F2 NAV2 MIR4486 GC11M019584
GH11H019563 1.2 Ensembl ENCODE dbSUPER 0.4 -10.9 -10936 1.4 CTCF ZNF654 MAZ RB1 TRIM22 REST ZNF2 RAD21 CC2D1A ZNF341 ENSG00000207407 NAV2-AS4 MIR4486 GC11M019543
GH11H019573 0.4 dbSUPER 0.7 -1.4 -1426 1.7 GLIS1 ZIC2 MIR4486 GC11M019543
GH11H019557 0.7 ENCODE 0.4 -17.5 -17462 0.2 GTF2F1 CTCF ZNF654 BHLHE40 INSM2 TRIM22 MAX REST RAD21 TEAD3 GC11M019543 MIR4486
GH11H019553 0.7 ENCODE 0.3 -21.4 -21392 0.1 CTCF ZNF654 RB1 ZNF10 TRIM22 REST ZNF2 RAD21 HIC1 MYNN GC11M019543 MIR4486
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4486 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4486 Gene

Genomic Locations for MIR4486 Gene
63 bases
Plus strand

Genomic View for MIR4486 Gene

Genes around MIR4486 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4486 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4486 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4486 Gene

Proteins for MIR4486 Gene

Post-translational modifications for MIR4486 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4486 Gene

Domains & Families for MIR4486 Gene

Gene Families for MIR4486 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4486: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4486 Gene

Function for MIR4486 Gene

Phenotypes From GWAS Catalog for MIR4486 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4486 Gene

Localization for MIR4486 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4486 Gene

Pathways & Interactions for MIR4486 Gene

SuperPathways for MIR4486 Gene

No Data Available

Interacting Proteins for MIR4486 Gene

Gene Ontology (GO) - Biological Process for MIR4486 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4486 Gene

Drugs & Compounds for MIR4486 Gene

No Compound Related Data Available

Transcripts for MIR4486 Gene

mRNA/cDNA for MIR4486 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4486 Gene

No ASD Table

Relevant External Links for MIR4486 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4486 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4486 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4486 Gene

Orthologs for MIR4486 Gene

Evolution for MIR4486 Gene

Gene Tree for MIR4486 (if available)
Gene Tree for MIR4486 (if available)

No data available for Orthologs for MIR4486 Gene

Paralogs for MIR4486 Gene

No data available for Paralogs for MIR4486 Gene

Variants for MIR4486 Gene

Sequence variations from dbSNP and Humsavar for MIR4486 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000615788 -- 19,575,114(+) TGCCA(A/G)GATGT intron-variant, upstream-variant-2KB
rs1003245323 -- 19,575,350(+) TAGAT(A/G)CTTGC intron-variant, nc-transcript-variant
rs1003324652 -- 19,573,810(+) GGGCT(A/G)GAAGG intron-variant, upstream-variant-2KB
rs1003968244 -- 19,574,401(+) GTTAA(C/T)TCCCT intron-variant, upstream-variant-2KB
rs1004147712 -- 19,573,743(+) AGCCC(A/T)CCCCT intron-variant, upstream-variant-2KB

Relevant External Links for MIR4486 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4486 Gene

Disorders for MIR4486 Gene

Relevant External Links for MIR4486

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4486 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4486 Gene

Publications for MIR4486 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4486 Gene

Sources for MIR4486 Gene

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