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Aliases for MIR4485 Gene

Subcategory (RNA class) for MIR4485 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4485 Gene

  • MicroRNA 4485 2 3 5
  • Hsa-Mir-4485 3
  • Mir-4485 3

External Ids for MIR4485 Gene

Previous GeneCards Identifiers for MIR4485 Gene

  • GC11U901877
  • GC11M010542
  • GC11M010549
  • GC11M010516
  • GC11M010523
  • GC11M010545
  • GC11M010557
  • GC11M010564
  • GC11M010569

Summaries for MIR4485 Gene

Entrez Gene Summary for MIR4485 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4485 Gene

MIR4485 (MicroRNA 4485) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4485 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4485 Gene

Genomics for MIR4485 Gene

Regulatory Elements for MIR4485 Gene

Enhancers for MIR4485 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H010502 1.2 FANTOM5 Ensembl ENCODE dbSUPER 0.7 +4.8 4826 2 MAX RNF141 MRVI1-AS1 AMPD3 CTR9 LYVE1 MRVI1 SBF2 ZBED5 EIF4G2 MIR4485
GH11H010487 1.8 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +18.3 18315 5 PKNOX1 ATF1 ARNT ZNF766 ATF7 FOS RUNX3 DEK REST ZNF592 LYVE1 AMPD3 MRVI1 ZBED5 GC11M010474 MIR4485
GH11H010505 0.8 ENCODE dbSUPER 0.7 +2.3 2318 1 JUN ZKSCAN8 HLF PRDM4 MRVI1-AS1 RNF141 CTR9 LYVE1 MRVI1 MIR4485 GC11M010474
GH11H010507 0.5 Ensembl ENCODE 0.7 +0.3 285 0 MRVI1-AS1 MIR4485 GC11M010474
GH11H010494 0.5 dbSUPER 0.4 +11.5 11453 4 CEBPB REST ZIC2 MRVI1-AS1 RNF141 AMPD3 MIR4485 GC11M010474
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4485 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4485 Gene

Chromosome:
11
Start:
10,508,270 bp from pter
End:
10,508,326 bp from pter
Size:
57 bases
Orientation:
Minus strand

Genomic View for MIR4485 Gene

Genes around MIR4485 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4485 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4485 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4485 Gene

Proteins for MIR4485 Gene

Post-translational modifications for MIR4485 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4485 Gene

Domains & Families for MIR4485 Gene

Gene Families for MIR4485 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4485: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4485 Gene

Function for MIR4485 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4485
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4485 Gene

Localization for MIR4485 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4485 Gene

Pathways & Interactions for MIR4485 Gene

SuperPathways for MIR4485 Gene

No Data Available

Interacting Proteins for MIR4485 Gene

Gene Ontology (GO) - Biological Process for MIR4485 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4485 Gene

Drugs & Compounds for MIR4485 Gene

No Compound Related Data Available

Transcripts for MIR4485 Gene

mRNA/cDNA for MIR4485 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4485
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4485 Gene

No ASD Table

Relevant External Links for MIR4485 Gene

GeneLoc Exon Structure for
MIR4485
ECgene alternative splicing isoforms for
MIR4485

Expression for MIR4485 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4485 Gene:

MIR4485
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4485 Gene

Orthologs for MIR4485 Gene

Evolution for MIR4485 Gene

ENSEMBL:
Gene Tree for MIR4485 (if available)
TreeFam:
Gene Tree for MIR4485 (if available)

No data available for Orthologs for MIR4485 Gene

Paralogs for MIR4485 Gene

No data available for Paralogs for MIR4485 Gene

Variants for MIR4485 Gene

Sequence variations from dbSNP and Humsavar for MIR4485 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000344130 -- 10,508,381(+) ATTTG(A/C)CGAGT upstream-variant-2KB, utr-variant-5-prime
rs1005664312 -- 10,510,101(+) CTTGA(C/T)ACCTG upstream-variant-2KB
rs1005695481 -- 10,509,858(+) AACTG(C/G)AGTTT upstream-variant-2KB
rs1005813493 -- 10,507,833(+) AGCTA(C/T)ACATG downstream-variant-500B
rs1006030691 -- 10,508,796(+) GGGTT(C/G/T)TGTGG upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for MIR4485 Gene

Variant ID Type Subtype PubMed ID
esv22967 CNV gain 19812545
esv3625358 CNV gain 21293372
nsv1044011 CNV gain 25217958
nsv972946 CNV duplication 23825009
nsv975881 CNV duplication 23825009

Relevant External Links for MIR4485 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4485

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4485 Gene

Disorders for MIR4485 Gene

Relevant External Links for MIR4485

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4485

No disorders were found for MIR4485 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4485 Gene

Publications for MIR4485 Gene

  1. Differential expression of microRNA in peripheral blood mononuclear cells as specific biomarker for major depressive disorder patients. (PMID: 25201637) Fan HM … Lu J (Journal of psychiatric research 2014) 3 60
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  3. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 60
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4485 Gene

Sources for MIR4485 Gene

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