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Aliases for MIR4485 Gene

Subcategory (RNA class) for MIR4485 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4485 Gene

  • MicroRNA 4485 2 3 5
  • Hsa-Mir-4485 3
  • Mir-4485 3

External Ids for MIR4485 Gene

Previous GeneCards Identifiers for MIR4485 Gene

  • GC11U901877
  • GC11M010542
  • GC11M010549
  • GC11M010516
  • GC11M010523
  • GC11M010545
  • GC11M010557
  • GC11M010564

Summaries for MIR4485 Gene

Entrez Gene Summary for MIR4485 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4485 Gene

MIR4485 (MicroRNA 4485) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4485 Gene

Genomics for MIR4485 Gene

Regulatory Elements for MIR4485 Gene

Enhancers for MIR4485 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G010502 1.3 FANTOM5 Ensembl ENCODE dbSUPER 0.7 +4.8 4826 2.2 ZNF512 MAX FOS RNF141 MRVI1-AS1 AMPD3 CTR9 LYVE1 MRVI1 SBF2 ZBED5 EIF4G2 MIR4485
GH11G010487 1.8 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +18.3 18315 5.2 PKNOX1 ATF1 ARNT SIN3A ZNF766 GATA2 ZMIZ1 FOS DEK JUNB LYVE1 AMPD3 MRVI1 ZBED5 MIR4485 GC11M010474
GH11G010505 1 ENCODE dbSUPER 0.7 +2.3 2318 1.9 PKNOX1 JUN HLF NR2F1 JUNB TBX21 JUND GATA2 EED IKZF1 MRVI1-AS1 RNF141 CTR9 LYVE1 MRVI1 MIR4485 GC11M010474
GH11G010507 0.5 Ensembl ENCODE 0.7 +0.3 285 0.5 MRVI1-AS1 MIR4485 GC11M010474
GH11G010473 0.7 dbSUPER 0.3 +29.0 29035 11.7 ZNF133 ZMYM3 ZIC2 ZKSCAN1 ZNF316 GATA2 POLR2A EGR1 SCRT2 FOS AMPD3 MTRNR2L8 LYVE1 MRVI1 GC11M010474 MIR4485
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4485 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4485 Gene

Chromosome:
11
Start:
10,508,270 bp from pter
End:
10,508,326 bp from pter
Size:
57 bases
Orientation:
Minus strand

Genomic View for MIR4485 Gene

Genes around MIR4485 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4485 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4485 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4485 Gene

Proteins for MIR4485 Gene

Post-translational modifications for MIR4485 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4485 Gene

Domains & Families for MIR4485 Gene

Gene Families for MIR4485 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4485: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4485 Gene

Function for MIR4485 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4485 Gene

Localization for MIR4485 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4485 Gene

Pathways & Interactions for MIR4485 Gene

SuperPathways for MIR4485 Gene

No Data Available

Interacting Proteins for MIR4485 Gene

Gene Ontology (GO) - Biological Process for MIR4485 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4485 Gene

Drugs & Compounds for MIR4485 Gene

No Compound Related Data Available

Transcripts for MIR4485 Gene

mRNA/cDNA for MIR4485 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4485 Gene

No ASD Table

Relevant External Links for MIR4485 Gene

GeneLoc Exon Structure for
MIR4485
ECgene alternative splicing isoforms for
MIR4485

Expression for MIR4485 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4485 Gene:

MIR4485
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4485 Gene

Orthologs for MIR4485 Gene

Evolution for MIR4485 Gene

ENSEMBL:
Gene Tree for MIR4485 (if available)
TreeFam:
Gene Tree for MIR4485 (if available)

No data available for Orthologs for MIR4485 Gene

Paralogs for MIR4485 Gene

No data available for Paralogs for MIR4485 Gene

Variants for MIR4485 Gene

Sequence variations from dbSNP and Humsavar for MIR4485 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000344130 -- 10,508,381(+) ATTTG(A/C)CGAGT upstream-variant-2KB, utr-variant-5-prime
rs1005664312 -- 10,510,101(+) CTTGA(C/T)ACCTG upstream-variant-2KB
rs1005695481 -- 10,509,858(+) AACTG(C/G)AGTTT upstream-variant-2KB
rs1005813493 -- 10,507,833(+) AGCTA(C/T)ACATG downstream-variant-500B
rs1006030691 -- 10,508,796(+) GGGTT(C/G/T)TGTGG upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for MIR4485 Gene

Variant ID Type Subtype PubMed ID
esv22967 CNV gain 19812545
esv3625358 CNV gain 21293372
nsv1044011 CNV gain 25217958
nsv972946 CNV duplication 23825009
nsv975881 CNV duplication 23825009

Relevant External Links for MIR4485 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4485

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4485 Gene

Disorders for MIR4485 Gene

Relevant External Links for MIR4485

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4485

No disorders were found for MIR4485 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4485 Gene

Publications for MIR4485 Gene

  1. Differential expression of microRNA in peripheral blood mononuclear cells as specific biomarker for major depressive disorder patients. (PMID: 25201637) Fan H.M. … Lu J. (J Psychiatr Res 2014) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4485 Gene

Sources for MIR4485 Gene

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