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Aliases for MIR4481 Gene

Subcategory (RNA class) for MIR4481 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4481 Gene

  • MicroRNA 4481 2 3 5
  • Hsa-Mir-4481 3

External Ids for MIR4481 Gene

Previous GeneCards Identifiers for MIR4481 Gene

  • GC10U901561

Summaries for MIR4481 Gene

Entrez Gene Summary for MIR4481 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4481 Gene

MIR4481 (MicroRNA 4481) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4481 Gene

Genomics for MIR4481 Gene

Regulatory Elements for MIR4481 Gene

Enhancers for MIR4481 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10F012656 0.7 ENCODE 0.8 -3.5 -3530 0.2 CTCF ZNF654 CBX3 ZNF140 TRIM22 ZNF501 REST RAD21 CBX5 KLF16 ENSG00000228302 ENSG00000239665 CAMK1D MIR548Q CCDC3 OPTN MIR4481 GC10P012703
GH10F012637 0.8 Ensembl ENCODE 0.4 +14.9 14946 0.9 ZNF664 KLF1 MAZ ZNF341 ZNF600 ZIC2 MIR548Q CAMK1D CCDC3 OPTN GC10M012628 MIR4481
GH10F012632 0.7 ENCODE 0.3 +20.7 20662 0.8 ELF3 TFAP4 PKNOX1 MNT ZNF48 ZNF121 ZNF341 HNF4G FOS HNF4A MIR548Q CAMK1D CCDC3 OPTN GC10M012628 MIR4481
GH10F012631 0.7 ENCODE 0.3 +21.2 21241 0.1 ELF3 PKNOX1 SAP130 FOXA3 MNT ZNF48 RAD21 ZNF121 FOS SETDB1 MIR548Q CAMK1D CCDC3 OPTN GC10M012628 MIR4481
GH10F012635 0.6 Ensembl 0.3 +17.8 17797 0.4 ZFP69B JUND ZNF692 POLR2A PRDM10 FOS MIR548Q CAMK1D CCDC3 OPTN GC10M012628 MIR4481
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4481 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4481 Gene

Chromosome:
10
Start:
12,653,138 bp from pter
End:
12,653,197 bp from pter
Size:
60 bases
Orientation:
Minus strand

Genomic View for MIR4481 Gene

Genes around MIR4481 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4481 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4481 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4481 Gene

Proteins for MIR4481 Gene

Post-translational modifications for MIR4481 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4481 Gene

Domains & Families for MIR4481 Gene

Gene Families for MIR4481 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4481: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4481 Gene

Function for MIR4481 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4481 Gene

Localization for MIR4481 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4481 Gene

Pathways & Interactions for MIR4481 Gene

SuperPathways for MIR4481 Gene

No Data Available

Interacting Proteins for MIR4481 Gene

Gene Ontology (GO) - Biological Process for MIR4481 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4481 Gene

Transcripts for MIR4481 Gene

mRNA/cDNA for MIR4481 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4481 Gene

No ASD Table

Relevant External Links for MIR4481 Gene

GeneLoc Exon Structure for
MIR4481
ECgene alternative splicing isoforms for
MIR4481

Expression for MIR4481 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4481 Gene:

MIR4481
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4481 Gene

Orthologs for MIR4481 Gene

Evolution for MIR4481 Gene

ENSEMBL:
Gene Tree for MIR4481 (if available)
TreeFam:
Gene Tree for MIR4481 (if available)

No data available for Orthologs for MIR4481 Gene

Paralogs for MIR4481 Gene

No data available for Paralogs for MIR4481 Gene

Variants for MIR4481 Gene

Sequence variations from dbSNP and Humsavar for MIR4481 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs10906196 -- 12,654,148(+) CCCAG(C/T)GTCTT intron-variant, upstream-variant-2KB
rs11257930 -- 12,654,121(+) ACCTC(A/G)AAGAT intron-variant, upstream-variant-2KB
rs116191316 -- 12,655,023(+) TAGCA(C/T)GTATC intron-variant, upstream-variant-2KB
rs116590673 -- 12,653,938(+) TGGTC(A/G)TGGGT intron-variant, upstream-variant-2KB
rs117848404 -- 12,653,803(+) CCAGT(A/T)GCTTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4481 Gene

Variant ID Type Subtype PubMed ID
esv3622363 CNV gain 21293372
nsv1041648 CNV gain 25217958
nsv831786 CNV loss 17160897

Relevant External Links for MIR4481 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4481

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4481 Gene

Disorders for MIR4481 Gene

Relevant External Links for MIR4481

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4481

No disorders were found for MIR4481 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4481 Gene

Publications for MIR4481 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4481 Gene

Sources for MIR4481 Gene

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