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Aliases for MIR4478 Gene

Subcategory (RNA class) for MIR4478 Gene


Quality Score for this RNA gene is


Aliases for MIR4478 Gene

  • MicroRNA 4478 2 3 5
  • Hsa-Mir-4478 3
  • Mir-4478 3

External Ids for MIR4478 Gene

Previous GeneCards Identifiers for MIR4478 Gene

  • GC09U901714
  • GC09M124884

Summaries for MIR4478 Gene

Entrez Gene Summary for MIR4478 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4478 Gene

MIR4478 (MicroRNA 4478) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4478 Gene

Genomics for MIR4478 Gene

Regulatory Elements for MIR4478 Gene

Enhancers for MIR4478 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F122123 0.8 ENCODE 0.8 -3.0 -3000 0.2 BCOR CTCF ESRRA ZMYM3 RAD21 TEAD3 ZNF143 SMC3 NR2F6 CREM MIR4478 NDUFA8
GH09F122122 0.8 Ensembl 0.8 -2.7 -2735 0.2 BCOR CTCF ESRRA ZMYM3 RAD21 TEAD3 ZNF143 NR2F6 DEK SMARCA5 DAB2IP MIR4478 NDUFA8
GH09F122134 1.2 Ensembl ENCODE 0.4 -14.8 -14834 0.8 TBP ATF1 ARID4B DMAP1 RAD21 ZSCAN9 YY1 RARA CREM THAP11 PTGS1 TTLL11 MIR4478 NDUFA8
GH09F122124 1.1 Ensembl ENCODE 0.4 -6.2 -6215 2.9 ELF3 PKNOX1 ARID4B DNMT3B ZNF2 RAD21 RFX5 ZNF143 RCOR1 CREM TTLL11 MRRF RBM18 PTGS1 OR1K1 MIR4478 NDUFA8
GH09F122116 0.5 ENCODE 0.8 +3.9 3921 0.2 POLR2A TEAD4 ZIC2 MIR4478 TTLL11
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4478 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4478 Gene

122,120,082 bp from pter
122,120,167 bp from pter
86 bases
Minus strand

Genomic View for MIR4478 Gene

Genes around MIR4478 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4478 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4478 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4478 Gene

Proteins for MIR4478 Gene

Post-translational modifications for MIR4478 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4478 Gene

Domains & Families for MIR4478 Gene

Gene Families for MIR4478 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4478: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4478 Gene

Function for MIR4478 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4478 Gene

Localization for MIR4478 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4478 Gene

Pathways & Interactions for MIR4478 Gene

SuperPathways for MIR4478 Gene

No Data Available

Interacting Proteins for MIR4478 Gene

Gene Ontology (GO) - Biological Process for MIR4478 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4478 Gene

Transcripts for MIR4478 Gene

mRNA/cDNA for MIR4478 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4478 Gene

No ASD Table

Relevant External Links for MIR4478 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4478 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4478 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4478 Gene:

genes like me logo Genes that share expression patterns with MIR4478: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4478 Gene

Orthologs for MIR4478 Gene

Evolution for MIR4478 Gene

Gene Tree for MIR4478 (if available)
Gene Tree for MIR4478 (if available)

No data available for Orthologs for MIR4478 Gene

Paralogs for MIR4478 Gene

No data available for Paralogs for MIR4478 Gene

Variants for MIR4478 Gene

Sequence variations from dbSNP and Humsavar for MIR4478 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs10116441 -- 122,119,736(+) gggca(A/G)ttttg downstream-variant-500B
rs10122562 -- 122,119,652(+) tccag(C/G)ctgga downstream-variant-500B
rs10985538 -- 122,121,728(+) TGCCC(C/T)AGGTG upstream-variant-2KB
rs10985539 -- 122,122,003(+) CTTTG(C/T)CCCAA upstream-variant-2KB
rs10985540 -- 122,122,091(+) GCCCA(C/T)TTGCC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4478 Gene

Variant ID Type Subtype PubMed ID
dgv7714n100 CNV gain 25217958
esv26681 CNV gain 19812545
nsv1036875 CNV gain 25217958
nsv525442 CNV gain 19592680
nsv831715 CNV gain 17160897

Relevant External Links for MIR4478 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4478 Gene

Disorders for MIR4478 Gene

Relevant External Links for MIR4478

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4478 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4478 Gene

Publications for MIR4478 Gene

  1. Decreased expression of fecal miR-4478 and miR-1295b-3p in early-stage colorectal cancer. (PMID: 25519020) Ghanbari R. … Knuutila S. (Cancer Biomark 2015) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4478 Gene

Sources for MIR4478 Gene

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