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Aliases for MIR4477B Gene

Subcategory (RNA class) for MIR4477B Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4477B Gene

  • MicroRNA 4477b 2 3
  • Hsa-Mir-4477b 3

External Ids for MIR4477B Gene

Previous GeneCards Identifiers for MIR4477B Gene

  • GC09U901734
  • GC09P068418
  • GC09P068421
  • GC09P068425

Summaries for MIR4477B Gene

Entrez Gene Summary for MIR4477B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4477B Gene

MIR4477B (MicroRNA 4477b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4477B Gene

Genomics for MIR4477B Gene

Genomic Location for MIR4477B Gene

Start:
63,819,574 bp from pter
End:
63,819,654 bp from pter
Size:
81 bases
Orientation:
Plus strand

Genomic View for MIR4477B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4477B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4477B Gene

No data available for Regulatory Elements for MIR4477B Gene

Proteins for MIR4477B Gene

Post-translational modifications for MIR4477B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4477B Gene

Domains for MIR4477B Gene

Gene Families for MIR4477B Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4477B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4477B Gene

Function for MIR4477B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR4477B Gene

Localization for MIR4477B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4477B Gene

Pathways for MIR4477B Gene

SuperPathways for MIR4477B Gene

No Data Available

Interacting Proteins for MIR4477B Gene

Gene Ontology (GO) - Biological Process for MIR4477B Gene

None

No data available for Pathways by source for MIR4477B Gene

Transcripts for MIR4477B Gene

mRNA/cDNA for MIR4477B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4477B Gene

No ASD Table

Relevant External Links for MIR4477B Gene

GeneLoc Exon Structure for
MIR4477B
ECgene alternative splicing isoforms for
MIR4477B

Expression for MIR4477B Gene

mRNA expression in normal human tissues for MIR4477B Gene

genes like me logo Genes that share expressions with MIR4477B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR4477B Gene

Orthologs for MIR4477B Gene

Evolution for MIR4477B Gene

ENSEMBL:
Gene Tree for MIR4477B (if available)
TreeFam:
Gene Tree for MIR4477B (if available)

No data available for Orthologs for MIR4477B Gene

Paralogs for MIR4477B Gene

No data available for Paralogs for MIR4477B Gene

Variants for MIR4477B Gene

Sequence variations from dbSNP and Humsavar for MIR4477B Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs901786 -- 63,817,662(+) CTCCA(C/T)ACCAA upstream-variant-2KB
rs1061921 -- 63,817,987(+) GGAGG(C/T)CTCCG upstream-variant-2KB
rs1136362 -- 63,818,779(+) ttctg(C/T)gctct upstream-variant-2KB
rs1806918 -- 63,818,066(+) TCCAG(C/G)CCCAC upstream-variant-2KB
rs1809617 -- 63,817,757(+) TCCAG(A/C/G)AGAGC upstream-variant-2KB

Relevant External Links for MIR4477B Gene

HapMap Linkage Disequilibrium report
MIR4477B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MIR4477B Gene

Disorders for MIR4477B Gene

No disorders were found for MIR4477B Gene.

No data available for UniProtKB/Swiss-Prot for MIR4477B Gene

Publications for MIR4477B Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3

Products for MIR4477B Gene

Sources for MIR4477B Gene

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