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Aliases for MIR4477A Gene

Subcategory (RNA class) for MIR4477A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4477A Gene

  • MicroRNA 4477a 2 3
  • Hsa-Mir-4477a 3

External Ids for MIR4477A Gene

Previous GeneCards Identifiers for MIR4477A Gene

  • GC09U901709
  • GC09P068417
  • GC09M068417

Summaries for MIR4477A Gene

Entrez Gene Summary for MIR4477A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4477A Gene

MIR4477A (MicroRNA 4477a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4477A Gene

Genomics for MIR4477A Gene

Genomic Location for MIR4477A Gene

Start:
41,233,755 bp from pter
End:
41,233,835 bp from pter
Size:
81 bases
Orientation:
Plus strand

Genomic View for MIR4477A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4477A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4477A Gene

No data available for Regulatory Elements for MIR4477A Gene

Proteins for MIR4477A Gene

Post-translational modifications for MIR4477A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4477A Gene

Domains for MIR4477A Gene

Gene Families for MIR4477A Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4477A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4477A Gene

Function for MIR4477A Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR4477A Gene

Localization for MIR4477A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4477A Gene

Pathways for MIR4477A Gene

SuperPathways for MIR4477A Gene

No Data Available

Interacting Proteins for MIR4477A Gene

Gene Ontology (GO) - Biological Process for MIR4477A Gene

None

No data available for Pathways by source for MIR4477A Gene

Transcripts for MIR4477A Gene

mRNA/cDNA for MIR4477A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4477A Gene

No ASD Table

Relevant External Links for MIR4477A Gene

GeneLoc Exon Structure for
MIR4477A
ECgene alternative splicing isoforms for
MIR4477A

Expression for MIR4477A Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR4477A Gene

Orthologs for MIR4477A Gene

Evolution for MIR4477A Gene

ENSEMBL:
Gene Tree for MIR4477A (if available)
TreeFam:
Gene Tree for MIR4477A (if available)

No data available for Orthologs for MIR4477A Gene

Paralogs for MIR4477A Gene

No data available for Paralogs for MIR4477A Gene

Variants for MIR4477A Gene

Sequence variations from dbSNP and Humsavar for MIR4477A Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs1586489 -- 63,820,203(+) ATGAC(G/T)TGGTA upstream-variant-2KB
rs1825857 -- 63,820,299(-) TATTA(A/G)TTATT upstream-variant-2KB
rs1825858 -- 63,820,431(-) GTGTA(A/G)GTTTT upstream-variant-2KB
rs1825859 -- 63,820,501(-) GGTTT(G/T)GTTCC upstream-variant-2KB
rs3177632 -- 63,820,245(+) CTGAC(A/G)TATTT upstream-variant-2KB

Relevant External Links for MIR4477A Gene

HapMap Linkage Disequilibrium report
MIR4477A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MIR4477A Gene

Disorders for MIR4477A Gene

No disorders were found for MIR4477A Gene.

No data available for UniProtKB/Swiss-Prot for MIR4477A Gene

Publications for MIR4477A Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3

Products for MIR4477A Gene

Sources for MIR4477A Gene

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