Aliases for MIR4476 Gene
Subcategory (RNA class) for MIR4476 Gene
miRNA
Quality Score for this RNA gene is
8
External Ids for MIR4476 Gene
- HGNC: 41793
- Entrez Gene: 100616456
- Ensembl: ENSG00000265368
- miRBase: hsa-mir-4476
ORGUL Members for MIR4476 Gene
Previous GeneCards Identifiers for MIR4476 Gene
- GC09U901713
Summaries for MIR4476 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR4476 Gene
MIR4476 (MicroRNA 4476) is an RNA Gene, and is affiliated with the miRNA class.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4476 Gene
Genomics for MIR4476 Gene
Regulatory Elements for MIR4476 Gene
Enhancers for MIR4476 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH09G036903 | 1.1 | ENCODE dbSUPER | 0.4 | -10.4 | -10378 | 0.2 | INSM2 KLF17 FEZF1 ZNF121 ZNF366 ZSCAN5C FOS USF2 ZEB2 ZNF843 | LOC105376032 PAX5 MIR4476 |
| GH09G036923 | 1.2 | ENCODE dbSUPER | 0.3 | -30.4 | -30436 | 1.4 | PKNOX1 FOXA2 INSM2 KLF17 SIN3A ZNF2 ZEB1 ZNF366 SCRT2 RCOR1 | MIR4476 LOC105376032 |
| GH09G036928 | 1.2 | ENCODE dbSUPER | 0.3 | -35.4 | -35408 | 0.2 | PKNOX1 INSM2 KLF17 FEZF1 ZNF2 GLIS2 ZSCAN5C FOS RELB ETV6 | MIR4476 LOC105376032 |
| GH09G036868 | 1 | ENCODE | 0.3 | +25.3 | 25323 | 0.2 | FOXA2 MLX ARID4B DMAP1 ZNF48 ZNF143 SP5 MXD4 MIER2 PPARG | MIR4540 MIR4476 |
| GH09G036924 | 0.8 | FANTOM5 dbSUPER | 0.3 | -31.5 | -31505 | 0.1 | CTCF KLF1 POLR2A TCF7L2 | MELK MIR4476 LOC105376032 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around MIR4476 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for MIR4476 Gene
- Chromosome:
- 9
- Start:
- 36,893,462 bp from pter
- End:
- 36,893,531 bp from pter
- Size:
- 70 bases
- Orientation:
- Minus strand
Genomic View for MIR4476 Gene
Genes around MIR4476 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9p13.2 by Ensembl
- 9p13.2 by Entrez Gene
- 9p13.2 by HGNC
MIR4476 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR4476 Gene
ORGUL Member Location for MIR4476 Gene
Proteins for MIR4476 Gene
Post-translational modifications for MIR4476 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MIR4476
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR4476
- Origene Custom Protein Services for MIR4476
- Search GeneTex for Proteins for MIR4476
No data available for DME Specific Peptides for MIR4476 Gene
Domains & Families for MIR4476 Gene
Gene Families for MIR4476 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4476 Gene
Function for MIR4476 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR4476
-
- Search ViGene Biosciences for MIR4476
CRISPR Products
- Browse CRISPR knockouts for MIR4476
miRNA Products
- Search ViGene Biosciences for MIR4476
-
Origene geneexpression products in human, mouse, rat for MIR4476
- Browse OriGene miRNA Products For MIR4476
Inhibitory RNA Products
- Search ViGene Biosciences for MIR4476
Clone Products
- GenScript: Custom all cDNA clones Services for MIR4476
- VectorBuilder custom plasmid, inducible vectors for MIR4476
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4476
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4476 Gene
Localization for MIR4476 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4476 Gene
Transcripts for MIR4476 Gene
mRNA/cDNA for MIR4476 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR4476
miRNA Products
- Search ViGene Biosciences for MIR4476
-
Origene geneexpression products in human, mouse, rat for MIR4476
- Browse OriGene miRNA Products For MIR4476
Inhibitory RNA Products
- Search ViGene Biosciences for MIR4476
Clone Products
- GenScript: Custom all cDNA clones Services for MIR4476
- VectorBuilder custom plasmid, inducible vectors for MIR4476
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4476
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for MIR4476 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR4476 Gene:
MIR4476
No Expression Related Data Available
Primer Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4476 Gene
Orthologs for MIR4476 Gene
No data available for Orthologs for MIR4476 Gene
Paralogs for MIR4476 Gene
No data available for Paralogs for MIR4476 Gene
Variants for MIR4476 Gene
| SNP ID | Clin | Chr 09 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000309182 | -- | 36,894,040(+) | GACCT(C/T)CAGGA | intron-variant, upstream-variant-2KB | |
| rs1001730561 | -- | 36,893,359(+) | TCCCA(A/G)GCTGG | intron-variant, downstream-variant-500B | |
| rs1001927032 | -- | 36,894,381(+) | AAATG(-/A)AAAAA | intron-variant, upstream-variant-2KB | |
| rs1001983567 | -- | 36,893,080(+) | CATGT(A/G)TGTAT | intron-variant, downstream-variant-500B | |
| rs1002396856 | -- | 36,895,040(+) | TGAGA(C/T)AGCTC | intron-variant, upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1125318 | OTHER | inversion | 24896259 |
| nsv438102 | CNV | loss | 16468122 |
Relevant External Links for MIR4476 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR4476
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4476 Gene
Disorders for MIR4476 Gene
Relevant External Links for MIR4476
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- MIR4476
No disorders were found for MIR4476 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4476 Gene
Publications for MIR4476 Gene
- miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
- Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
Products for MIR4476 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
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- Browse OriGene Antibodies
- Custom Antibody Services
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- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR4476
- Origene Custom Protein Services for MIR4476
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- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for MIR4476
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Origene geneexpression products in human, mouse, rat for MIR4476
- Browse OriGene miRNA Products For MIR4476
- GenScript: Custom all cDNA clones Services for MIR4476
- GenScript Custom Purified and Recombinant Proteins Services for MIR4476
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- GenScript Custom overexpressing Cell Line Services for MIR4476
- Browse GenScript CRISPR for MIR4476
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for MIR4476
- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Search GeneTex for Antibodies for MIR4476
- Search GeneTex for Proteins for MIR4476
- Search ViGene Biosciences for MIR4476
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR4476
- VectorBuilder custom plasmid, inducible vectors for MIR4476
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR4476
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for MIR4476 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer