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MIR4476 Gene(RNA Gene)

MicroRNA 4476

GCID:
GC09M036895
GIFtS:
14
Genes Participants
UDN Logo

Aliases for MIR4476 Gene

Subcategory (RNA class) for MIR4476 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4476 Gene

  • MicroRNA 4476 2 3 5
  • Hsa-Mir-4476 3
  • Mir-4476 3

External Ids for MIR4476 Gene

ORGUL Members for MIR4476 Gene

Previous GeneCards Identifiers for MIR4476 Gene

  • GC09U901713

Summaries for MIR4476 Gene

Entrez Gene Summary for MIR4476 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4476 Gene

MIR4476 (MicroRNA 4476) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4476 Gene

Genomics for MIR4476 Gene

Products:

  1. Regulatory Element

Regulatory Elements for MIR4476 Gene

Enhancers for MIR4476 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F036903 0.8 ENCODE 0.4 -10.4 -10378 0.2 USF1 JUN INSM2 KLF17 FEZF1 FOSL1 ZNF121 HIC1 ZNF366 PATZ1 LOC105376032 PAX5 MIR4476
GH09F036868 1 ENCODE 0.3 +25.3 25323 0.2 MLX ARID4B DMAP1 ZNF48 SP5 MXD4 MIER2 PPARG KAT8 NFIL3 MIR4540 MIR4476
GH09F036928 0.9 ENCODE 0.3 -35.4 -35408 0.2 PKNOX1 INSM2 KLF17 FEZF1 ZNF2 GLIS2 ETV6 FOS EGR2 OVOL3 MIR4476 LOC105376032
GH09F036923 0.9 ENCODE 0.3 -30.4 -30436 1.4 PKNOX1 INSM2 KLF17 SIN3A ZNF2 ZEB1 ZNF366 SCRT2 ETV6 RCOR1 MIR4476 LOC105376032
GH09F036873 0.7 ENCODE 0.3 +20.1 20073 0.2 CTCF EBF1 ZNF2 RAD21 HBP1 HIC1 POLR2A SCRT2 ZNF143 SMC3 MIR4540 MIR4476
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4476 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4476 Gene

Chromosome:
9
Start:
36,893,462 bp from pter
End:
36,893,531 bp from pter
Size:
70 bases
Orientation:
Minus strand

Genomic View for MIR4476 Gene

Genes around MIR4476 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4476 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4476 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR4476 Gene

ORGUL Member Location for MIR4476 Gene

ORGUL Member Location for MIR4476 gene

Proteins for MIR4476 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR4476 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4476 Gene

Domains & Families for MIR4476 Gene

Gene Families for MIR4476 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4476: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4476 Gene

Function for MIR4476 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4476 Gene

Localization for MIR4476 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4476 Gene

Pathways & Interactions for MIR4476 Gene

SuperPathways for MIR4476 Gene

PathCards logo More details on SuperPathways for MIR4476
No Data Available

Interacting Proteins for MIR4476 Gene

Gene Ontology (GO) - Biological Process for MIR4476 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4476 Gene

Drugs & Compounds for MIR4476 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR4476 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for MIR4476 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4476 Gene

No ASD Table

Relevant External Links for MIR4476 Gene

GeneLoc Exon Structure for
MIR4476
ECgene alternative splicing isoforms for
MIR4476

Expression for MIR4476 Gene

Products:

  1. Primer

NURSA nuclear receptor signaling pathways regulating expression of MIR4476 Gene:

MIR4476
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4476 Gene

Orthologs for MIR4476 Gene

Evolution for MIR4476 Gene

ENSEMBL:
Gene Tree for MIR4476 (if available)
TreeFam:
Gene Tree for MIR4476 (if available)

No data available for Orthologs for MIR4476 Gene

Paralogs for MIR4476 Gene

No data available for Paralogs for MIR4476 Gene

Variants for MIR4476 Gene

Sequence variations from dbSNP and Humsavar for MIR4476 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs10758412 -- 36,894,659(+) ACATG(G/T)ATTAA intron-variant, upstream-variant-2KB
rs10814467 -- 36,895,102(+) CCCTA(C/T)CACAC intron-variant, upstream-variant-2KB
rs10814468 -- 36,895,147(+) GGTCC(A/G)AATAA intron-variant, upstream-variant-2KB
rs10973119 -- 36,894,500(+) TGTGC(A/G)ATGGG intron-variant, upstream-variant-2KB
rs10973120 -- 36,895,385(+) TATGA(A/G)GTAGA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4476 Gene

Variant ID Type Subtype PubMed ID
nsv1125318 OTHER inversion 24896259
nsv438102 CNV loss 16468122

Relevant External Links for MIR4476 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4476

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4476 Gene

Disorders for MIR4476 Gene

Relevant External Links for MIR4476

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4476

No disorders were found for MIR4476 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4476 Gene

Publications for MIR4476 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4476 Gene

Sources for MIR4476 Gene

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