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Aliases for MIR4475 Gene

Subcategory (RNA class) for MIR4475 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4475 Gene

  • MicroRNA 4475 2 3 5
  • Hsa-Mir-4475 3

External Ids for MIR4475 Gene

Previous GeneCards Identifiers for MIR4475 Gene

  • GC09U901717

Summaries for MIR4475 Gene

Entrez Gene Summary for MIR4475 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4475 Gene

MIR4475 (MicroRNA 4475) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4475 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4475 Gene

Genomics for MIR4475 Gene

GeneHancer (GH) Regulatory Elements for MIR4475 Gene

Promoters and enhancers for MIR4475 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09I036819 Enhancer 0.5 ENCODE 0.8 +4.5 4460 0.2 MEIS2 PKNOX1 POLR2A SIN3A EZH2 MIR4475 LOC105376030
GH09I036818 Enhancer 0.3 Ensembl 0.8 +4.9 4898 0.2 EZH2 MIR4475 LOC105376030
GH09I036855 Enhancer 0.6 ENCODE 0.3 -32.1 -32060 0.2 HDGF BCOR CTCF RFX1 ZMYM3 EBF1 RAD21 ZFHX2 ZNF143 ZFP36 ENSG00000258885 GC09M036839 ENSG00000260100 MIR4475 PAX5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4475 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4475 Gene

Genomic Locations for MIR4475 Gene
chr9:36,823,539-36,823,599
(GRCh38/hg38)
Size:
61 bases
Orientation:
Minus strand
chr9:36,823,536-36,823,596
(GRCh37/hg19)

Genomic View for MIR4475 Gene

Genes around MIR4475 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4475 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4475 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4475 Gene

Proteins for MIR4475 Gene

Post-translational modifications for MIR4475 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4475 Gene

Domains & Families for MIR4475 Gene

Gene Families for MIR4475 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4475: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4475 Gene

Function for MIR4475 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4475 Gene

Localization for MIR4475 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4475 Gene

Pathways & Interactions for MIR4475 Gene

SuperPathways for MIR4475 Gene

No Data Available

Interacting Proteins for MIR4475 Gene

Gene Ontology (GO) - Biological Process for MIR4475 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4475 Gene

Drugs & Compounds for MIR4475 Gene

No Compound Related Data Available

Transcripts for MIR4475 Gene

mRNA/cDNA for MIR4475 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4475 Gene

No ASD Table

Relevant External Links for MIR4475 Gene

GeneLoc Exon Structure for
MIR4475
ECgene alternative splicing isoforms for
MIR4475

Expression for MIR4475 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4475 Gene:

MIR4475
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4475 Gene

Orthologs for MIR4475 Gene

Evolution for MIR4475 Gene

ENSEMBL:
Gene Tree for MIR4475 (if available)
TreeFam:
Gene Tree for MIR4475 (if available)

No data available for Orthologs for MIR4475 Gene

Paralogs for MIR4475 Gene

No data available for Paralogs for MIR4475 Gene

Variants for MIR4475 Gene

Sequence variations from dbSNP and Humsavar for MIR4475 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000115359 -- 36,825,397(-) T/C upstream_transcript_variant
rs1003285995 -- 36,824,627(-) A/C upstream_transcript_variant
rs1003690249 -- 36,823,707(-) A/C upstream_transcript_variant
rs1004699490 -- 36,823,346(-) C/T downstream_transcript_variant
rs1007668593 -- 36,825,003(-) C/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4475 Gene

Variant ID Type Subtype PubMed ID
nsv1125318 OTHER inversion 24896259
nsv471306 CNV loss 18288195

Additional Variant Information for MIR4475 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4475

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4475 Gene

Disorders for MIR4475 Gene

Additional Disease Information for MIR4475

No disorders were found for MIR4475 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4475 Gene

Publications for MIR4475 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4475 Gene

Sources for MIR4475 Gene

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