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Aliases for MIR4474 Gene

Subcategory (RNA class) for MIR4474 Gene


Quality Score for this RNA gene is


Aliases for MIR4474 Gene

  • MicroRNA 4474 2 3 5
  • Hsa-Mir-4474 3

External Ids for MIR4474 Gene

Previous GeneCards Identifiers for MIR4474 Gene

  • GC09U901719

Summaries for MIR4474 Gene

Entrez Gene Summary for MIR4474 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4474 Gene

MIR4474 (MicroRNA 4474) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4474 Gene

Genomics for MIR4474 Gene

Regulatory Elements for MIR4474 Gene

Enhancers for MIR4474 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F020511 0.9 Ensembl ENCODE 0.4 -10.4 -10409 2.1 SIN3A FEZF1 EP300 ZNF23 MAFF JUND ZSCAN16 MLLT1 MAFK ZBTB17 MLLT3 MIR4474 RPL7AP48
GH09F020477 1 Ensembl ENCODE 0.3 +25.2 25242 0.2 GATAD2A SOX13 SOX5 PKNOX1 TEAD1 SP5 RARA TEAD3 TCF7 SMAD4 MIR4474 RNU4-26P
GH09F020507 0.7 Ensembl 0.4 -5.5 -5460 1.6 FEZF1 CTBP1 GATA3 KLF8 MTA2 JUNB CEBPB ZNF843 OSR2 SMARCA4 MIR4474 RPL7AP48
GH09F020478 0.6 Ensembl 0.3 +23.8 23841 1.0 PKNOX1 FEZF1 RAD21 ZNF366 WT1 TRIM28 SP7 ZBTB17 MIR4474 RNU4-26P
GH09F020505 0.2 ENCODE 0.8 -2.8 -2766 0.1 MIR4474 RPL7AP48
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4474 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4474 Gene

20,502,265 bp from pter
20,502,342 bp from pter
78 bases
Minus strand

Genomic View for MIR4474 Gene

Genes around MIR4474 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4474 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4474 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4474 Gene

Proteins for MIR4474 Gene

Post-translational modifications for MIR4474 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4474 Gene

Domains & Families for MIR4474 Gene

Gene Families for MIR4474 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4474: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4474 Gene

Function for MIR4474 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4474 Gene

Localization for MIR4474 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4474 Gene

Pathways & Interactions for MIR4474 Gene

SuperPathways for MIR4474 Gene

No Data Available

Interacting Proteins for MIR4474 Gene

Gene Ontology (GO) - Biological Process for MIR4474 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4474 Gene

Transcripts for MIR4474 Gene

mRNA/cDNA for MIR4474 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4474 Gene

No ASD Table

Relevant External Links for MIR4474 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4474 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4474 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4474 Gene:

genes like me logo Genes that share expression patterns with MIR4474: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4474 Gene

Orthologs for MIR4474 Gene

Evolution for MIR4474 Gene

Gene Tree for MIR4474 (if available)
Gene Tree for MIR4474 (if available)

No data available for Orthologs for MIR4474 Gene

Paralogs for MIR4474 Gene

No data available for Paralogs for MIR4474 Gene

Variants for MIR4474 Gene

Sequence variations from dbSNP and Humsavar for MIR4474 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs10465020 -- 20,502,451(+) acgtg(A/G)tctta intron-variant, upstream-variant-2KB
rs10811354 -- 20,502,952(+) CACTA(C/T)AGCAA intron-variant, upstream-variant-2KB
rs10964580 -- 20,501,900(+) ATATG(C/G)TGAAA intron-variant, downstream-variant-500B
rs10964581 -- 20,501,926(+) AAATA(C/T)AAAAA intron-variant, downstream-variant-500B
rs111940935 -- 20,502,255(+) GAAGT(A/G)TGGTT intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4474 Gene

Variant ID Type Subtype PubMed ID
esv3576641 CNV gain 25503493

Relevant External Links for MIR4474 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4474 Gene

Disorders for MIR4474 Gene

Relevant External Links for MIR4474

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4474 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4474 Gene

Publications for MIR4474 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D. … den Boer M.L. (Leukemia 2011) 3 64
  3. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4474 Gene

Sources for MIR4474 Gene

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