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Aliases for MIR4473 Gene

Subcategory (RNA class) for MIR4473 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4473 Gene

  • MicroRNA 4473 2 3 5
  • Hsa-Mir-4473 3

External Ids for MIR4473 Gene

Previous GeneCards Identifiers for MIR4473 Gene

  • GC09U901732

Summaries for MIR4473 Gene

Entrez Gene Summary for MIR4473 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4473 Gene

MIR4473 (MicroRNA 4473) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4473 Gene

Genomics for MIR4473 Gene

Regulatory Elements for MIR4473 Gene

Enhancers for MIR4473 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09G020408 0.8 ENCODE 0.7 +2.6 2573 1.0 PKNOX1 ARNT ZNF384 FEZF1 ZIC2 CTBP1 ZNF600 TCF7L2 SCRT1 BHLHE40 MIR4473 GC09M020330
GH09G020382 0.9 ENCODE 0.3 +28.3 28341 0.3 PKNOX1 FOXA2 ARNT KLF17 INSM2 SIN3A FEZF1 ZNF2 RARA ZSCAN5C MIR4473 GC09M020330
GH09G020353 1.2 Ensembl ENCODE 0.2 +55.9 55851 4.3 PKNOX1 ARID4B FEZF1 ZNF48 RAD21 YY1 ZNF366 ZSCAN5C CREM DEK MLLT3 GC09M020330 MIR4473
GH09G020376 0.6 ENCODE 0.3 +34.4 34359 1.2 GATAD2A SOX13 CEBPA CEBPB CEBPG PRDM1 MIR4473 GC09M020330
GH09G020398 0.2 ENCODE 0.4 +12.5 12461 0.2 MIR4473 GC09M020330
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4473 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4473 Gene

Chromosome:
9
Start:
20,411,148 bp from pter
End:
20,411,238 bp from pter
Size:
91 bases
Orientation:
Minus strand

Genomic View for MIR4473 Gene

Genes around MIR4473 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4473 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4473 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4473 Gene

Proteins for MIR4473 Gene

Post-translational modifications for MIR4473 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4473 Gene

Domains & Families for MIR4473 Gene

Gene Families for MIR4473 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4473: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4473 Gene

Function for MIR4473 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4473 Gene

Localization for MIR4473 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4473 Gene

Pathways & Interactions for MIR4473 Gene

SuperPathways for MIR4473 Gene

No Data Available

Interacting Proteins for MIR4473 Gene

Gene Ontology (GO) - Biological Process for MIR4473 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4473 Gene

Drugs & Compounds for MIR4473 Gene

No Compound Related Data Available

Transcripts for MIR4473 Gene

mRNA/cDNA for MIR4473 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4473 Gene

No ASD Table

Relevant External Links for MIR4473 Gene

GeneLoc Exon Structure for
MIR4473
ECgene alternative splicing isoforms for
MIR4473

Expression for MIR4473 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4473 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4473 Gene:

MIR4473
genes like me logo Genes that share expression patterns with MIR4473: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4473 Gene

Orthologs for MIR4473 Gene

Evolution for MIR4473 Gene

ENSEMBL:
Gene Tree for MIR4473 (if available)
TreeFam:
Gene Tree for MIR4473 (if available)

No data available for Orthologs for MIR4473 Gene

Paralogs for MIR4473 Gene

No data available for Paralogs for MIR4473 Gene

Variants for MIR4473 Gene

Sequence variations from dbSNP and Humsavar for MIR4473 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1002991343 -- 20,412,181(+) CAACA(G/T)CATTT intron-variant, upstream-variant-2KB
rs1003106855 -- 20,412,426(+) GTCCT(A/C)ATCTG intron-variant, upstream-variant-2KB
rs1003411992 -- 20,411,292(+) CCAAA(C/T)AAAGC intron-variant, upstream-variant-2KB
rs1003685637 -- 20,411,119(+) GCCTG(C/T)CCCAA intron-variant, downstream-variant-500B
rs1006893812 -- 20,412,538(+) ACCCA(G/T)AACAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4473 Gene

Variant ID Type Subtype PubMed ID
esv3576640 CNV gain 25503493
esv3576641 CNV gain 25503493
nsv1023995 CNV gain 25217958
nsv613745 CNV loss 21841781

Relevant External Links for MIR4473 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4473

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4473 Gene

Disorders for MIR4473 Gene

Relevant External Links for MIR4473

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4473

No disorders were found for MIR4473 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4473 Gene

Publications for MIR4473 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4473 Gene

Sources for MIR4473 Gene

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