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Aliases for MIR4463 Gene

Subcategory (RNA class) for MIR4463 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4463 Gene

  • MicroRNA 4463 2 3 5
  • Hsa-Mir-4463 3

External Ids for MIR4463 Gene

Previous GeneCards Identifiers for MIR4463 Gene

  • GC06U902222
  • GC06P076140

Summaries for MIR4463 Gene

Entrez Gene Summary for MIR4463 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4463 Gene

MIR4463 (MicroRNA 4463) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4463 Gene

Genomics for MIR4463 Gene

Regulatory Elements for MIR4463 Gene

Enhancers for MIR4463 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06G075430 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.7 +3.1 3087 2.1 RFX1 JUN GFI1B ZEB2 ZNF398 ZNF507 ZSCAN21 JUND SCRT2 FOS FILIP1 RNU1-34P RPL26P20 SENP6 MIR4463 PIR50339
GH06G075425 0.7 ENCODE 0.7 -3.1 -3068 0.1 RFX1 JUN ZNF843 EP300 OSR2 JUND PRDM6 IKZF1 FOSL2 FOS MIR4463 GC06P075402
GH06G075413 1.2 ENCODE dbSUPER 0.4 -14.8 -14832 1.0 FEZF1 FOS KLF7 TSHZ1 ZNF488 MBD2 GLIS1 STAT3 WT1 PRDM4 MIR4463 GC06P075402
GH06G075436 1 Ensembl ENCODE dbSUPER 0.4 +9.4 9436 3.1 ZNF146 FOS EP300 FILIP1 RNU1-34P RPL26P20 MIR4463 PIR50339
GH06G075419 0.9 FANTOM5 ENCODE 0.4 -10.0 -9963 0.3 MAFF JUND ZNF316 MTA2 JUN CEBPB NR3C1 FOS MAFK FILIP1 RPL26P20 MIR4463 GC06P075402
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4463 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4463 Gene

Chromosome:
6
Start:
75,428,407 bp from pter
End:
75,428,473 bp from pter
Size:
67 bases
Orientation:
Plus strand

Genomic View for MIR4463 Gene

Genes around MIR4463 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4463 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4463 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4463 Gene

Proteins for MIR4463 Gene

Post-translational modifications for MIR4463 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4463 Gene

Domains & Families for MIR4463 Gene

Gene Families for MIR4463 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4463: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4463 Gene

Function for MIR4463 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4463 Gene

Localization for MIR4463 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4463 Gene

Pathways & Interactions for MIR4463 Gene

SuperPathways for MIR4463 Gene

No Data Available

Interacting Proteins for MIR4463 Gene

Gene Ontology (GO) - Biological Process for MIR4463 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4463 Gene

Drugs & Compounds for MIR4463 Gene

No Compound Related Data Available

Transcripts for MIR4463 Gene

mRNA/cDNA for MIR4463 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4463 Gene

No ASD Table

Relevant External Links for MIR4463 Gene

GeneLoc Exon Structure for
MIR4463
ECgene alternative splicing isoforms for
MIR4463

Expression for MIR4463 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4463 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4463 Gene:

MIR4463
genes like me logo Genes that share expression patterns with MIR4463: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4463 Gene

Orthologs for MIR4463 Gene

Evolution for MIR4463 Gene

ENSEMBL:
Gene Tree for MIR4463 (if available)
TreeFam:
Gene Tree for MIR4463 (if available)

No data available for Orthologs for MIR4463 Gene

Paralogs for MIR4463 Gene

No data available for Paralogs for MIR4463 Gene

Variants for MIR4463 Gene

Sequence variations from dbSNP and Humsavar for MIR4463 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000954748 -- 75,426,728(+) GAACC(A/C)TGGGC intron-variant, upstream-variant-2KB
rs1001596022 -- 75,426,782(+) ACAGG(C/T)AGGAT intron-variant, upstream-variant-2KB
rs1001710642 -- 75,427,209(+) ATAGA(C/T)TAAGT intron-variant, upstream-variant-2KB
rs1002863390 -- 75,428,807(+) CAGAC(A/G)TGGTT intron-variant, downstream-variant-500B
rs1003268622 -- 75,428,756(+) GTTTA(A/G)ACTTG intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4463 Gene

Variant ID Type Subtype PubMed ID
esv3890880 CNV loss 25118596

Relevant External Links for MIR4463 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4463

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4463 Gene

Disorders for MIR4463 Gene

Relevant External Links for MIR4463

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4463

No disorders were found for MIR4463 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4463 Gene

Publications for MIR4463 Gene

  1. Altered Plasma MicroRNAs as Novel Biomarkers for Arteriosclerosis Obliterans. (PMID: 26370316) He X.M. … Zhou X.Y. (J. Atheroscler. Thromb. 2015) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4463 Gene

Sources for MIR4463 Gene

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