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Aliases for MIR4462 Gene

Subcategory (RNA class) for MIR4462 Gene


Quality Score for this RNA gene is


Aliases for MIR4462 Gene

  • MicroRNA 4462 2 3 5
  • Hsa-Mir-4462 3

External Ids for MIR4462 Gene

Previous GeneCards Identifiers for MIR4462 Gene

  • GC06U902214
  • GC06M037525

Summaries for MIR4462 Gene

Entrez Gene Summary for MIR4462 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4462 Gene

MIR4462 (MicroRNA 4462) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4462 Gene

Genomics for MIR4462 Gene

Regulatory Elements for MIR4462 Gene

Enhancers for MIR4462 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F037546 0.9 FANTOM5 Ensembl ENCODE 0.8 +4.3 4266 10.3 HDGF PKNOX1 WRNIP1 ZFP64 SIN3A YY1 ZNF143 ZNF207 FOS ZNF263 LOC100505530 CCDC167 CMTR1 ENSG00000229559 MIR4462
GH06F037556 1.3 FANTOM5 ENCODE 0.8 -1.7 -1704 1.0 HDGF TBP MAZ STAT1 SMAD5 BHLHE40 EBF1 REST RELA POLR2A LOC100505530 CCDC167 MIR4462 ENSG00000279942
GH06F037559 1 FANTOM5 ENCODE 0.4 -7.5 -7540 7.9 HDGF ZNF493 ZNF2 ZNF121 ZNF302 ZNF143 FOS ZNF202 NFYC REST CMTR1 CCDC167 LOC100505530 MDGA1 TMEM217 ENSG00000279942 MIR4462
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4462 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4462 Gene

37,555,365 bp from pter
37,555,422 bp from pter
58 bases
Minus strand

Genomic View for MIR4462 Gene

Genes around MIR4462 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4462 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4462 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4462 Gene

Proteins for MIR4462 Gene

Post-translational modifications for MIR4462 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4462 Gene

Domains & Families for MIR4462 Gene

Gene Families for MIR4462 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4462: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4462 Gene

Function for MIR4462 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4462 Gene

Localization for MIR4462 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4462 Gene

Pathways & Interactions for MIR4462 Gene

SuperPathways for MIR4462 Gene

No Data Available

Interacting Proteins for MIR4462 Gene

Gene Ontology (GO) - Biological Process for MIR4462 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4462 Gene

Transcripts for MIR4462 Gene

mRNA/cDNA for MIR4462 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4462 Gene

No ASD Table

Relevant External Links for MIR4462 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4462 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4462 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4462 Gene

Orthologs for MIR4462 Gene

Evolution for MIR4462 Gene

Gene Tree for MIR4462 (if available)
Gene Tree for MIR4462 (if available)

No data available for Orthologs for MIR4462 Gene

Paralogs for MIR4462 Gene

No data available for Paralogs for MIR4462 Gene

Variants for MIR4462 Gene

Sequence variations from dbSNP and Humsavar for MIR4462 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs114532997 -- 37,556,030(+) CTCTC(A/G)GGCAT upstream-variant-2KB
rs116377297 -- 37,555,799(+) TGGAA(C/T)GGGGA upstream-variant-2KB
rs11757931 -- 37,555,753(+) GCTCA(G/T)GGGAG upstream-variant-2KB
rs12529621 -- 37,557,118(+) TCCCC(A/C/G)TCCGG upstream-variant-2KB
rs138910605 -- 37,555,923(+) AGATT(C/T)TCTCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4462 Gene

Variant ID Type Subtype PubMed ID
esv1006017 CNV deletion 20482838
esv2752124 CNV gain 17911159
nsv1015689 CNV gain 25217958
nsv1016310 CNV gain 25217958

Relevant External Links for MIR4462 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4462 Gene

Disorders for MIR4462 Gene

Relevant External Links for MIR4462

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4462 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4462 Gene

Publications for MIR4462 Gene

  1. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini A.A. … Barker J.N. (Nat Commun 2014) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4462 Gene

Sources for MIR4462 Gene

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