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Aliases for MIR4461 Gene

Subcategory (RNA class) for MIR4461 Gene


Quality Score for this RNA gene is


Aliases for MIR4461 Gene

  • MicroRNA 4461 2 3 5
  • Hsa-Mir-4461 3
  • Mir-4461 3

External Ids for MIR4461 Gene

Previous GeneCards Identifiers for MIR4461 Gene

  • GC05U901562
  • GC05M134307
  • GC05M134310
  • GC05M134317
  • GC05P134266

Summaries for MIR4461 Gene

Entrez Gene Summary for MIR4461 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4461 Gene

MIR4461 (MicroRNA 4461) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4461 Gene

Genomics for MIR4461 Gene

Regulatory Elements for MIR4461 Gene

Enhancers for MIR4461 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05F134928 0.6 ENCODE 0.8 +0.2 227 0.2 MTND4LP30 MIR4461
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4461 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4461 Gene

134,928,039 bp from pter
134,928,112 bp from pter
74 bases
Plus strand

Genomic View for MIR4461 Gene

Genes around MIR4461 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4461 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4461 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4461 Gene

Proteins for MIR4461 Gene

Post-translational modifications for MIR4461 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4461 Gene

Domains & Families for MIR4461 Gene

Gene Families for MIR4461 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4461: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4461 Gene

Function for MIR4461 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4461 Gene

Localization for MIR4461 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4461 Gene

Pathways & Interactions for MIR4461 Gene

SuperPathways for MIR4461 Gene

No Data Available

Interacting Proteins for MIR4461 Gene

Gene Ontology (GO) - Biological Process for MIR4461 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4461 Gene

Transcripts for MIR4461 Gene

mRNA/cDNA for MIR4461 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4461 Gene

No ASD Table

Relevant External Links for MIR4461 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4461 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4461 Gene

mRNA expression in normal human tissues for MIR4461 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4461 Gene:

genes like me logo Genes that share expression patterns with MIR4461: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4461 Gene

Orthologs for MIR4461 Gene

Evolution for MIR4461 Gene

Gene Tree for MIR4461 (if available)
Gene Tree for MIR4461 (if available)

No data available for Orthologs for MIR4461 Gene

Paralogs for MIR4461 Gene

No data available for Paralogs for MIR4461 Gene

Variants for MIR4461 Gene

Sequence variations from dbSNP and Humsavar for MIR4461 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs10155566 -- 134,926,987(+) AGTAG(A/G)GTTTG intron-variant, upstream-variant-2KB
rs111258738 -- 134,928,108(+) AGGCC(C/T)ACTGC intron-variant, nc-transcript-variant
rs111345549 -- 134,927,461(+) AAGTT(A/G)TTGGC intron-variant, upstream-variant-2KB
rs111618963 -- 134,928,398(-) TTCGG(A/G)TCAGT intron-variant, downstream-variant-500B
rs111740989 -- 134,927,923(+) AGTAG(A/G)GGGAT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4461 Gene

Variant ID Type Subtype PubMed ID
dgv968n67 CNV gain 20364138
esv22702 CNV gain+loss 19812545
esv2511005 CNV gain 19546169
nsv599736 CNV gain 21841781
nsv599742 CNV gain+loss 21841781
nsv819528 CNV loss 19587683
nsv830494 CNV gain+loss 17160897
nsv950397 CNV duplication 24416366
nsv964940 CNV duplication 23825009

Relevant External Links for MIR4461 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4461 Gene

Disorders for MIR4461 Gene

Relevant External Links for MIR4461

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4461 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4461 Gene

Publications for MIR4461 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4461 Gene

Sources for MIR4461 Gene

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