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Aliases for MIR4460 Gene

Subcategory (RNA class) for MIR4460 Gene


Quality Score for this RNA gene is


Aliases for MIR4460 Gene

  • MicroRNA 4460 2 3
  • Hsa-Mir-4460 3

External Ids for MIR4460 Gene

Previous GeneCards Identifiers for MIR4460 Gene

  • GC05U901580
  • GC05M128734

Summaries for MIR4460 Gene

Entrez Gene Summary for MIR4460 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4460 Gene

MIR4460 (MicroRNA 4460) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4460 Gene

Genomics for MIR4460 Gene

Genomic Location for MIR4460 Gene

129,397,062 bp from pter
129,397,147 bp from pter
86 bases
Minus strand

Genomic View for MIR4460 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4460 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4460 Gene

ORGUL Member Location for MIR4460 Gene

ORGUL Member Location for MIR4460 gene

No data available for Regulatory Elements for MIR4460 Gene

Proteins for MIR4460 Gene

Post-translational modifications for MIR4460 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4460 Gene

Domains for MIR4460 Gene

Gene Families for MIR4460 Gene

  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4460: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4460 Gene

Function for MIR4460 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR4460 Gene

Localization for MIR4460 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4460 Gene

Pathways for MIR4460 Gene

SuperPathways for MIR4460 Gene

No Data Available

Interacting Proteins for MIR4460 Gene

Gene Ontology (GO) - Biological Process for MIR4460 Gene


No data available for Pathways by source for MIR4460 Gene

Transcripts for MIR4460 Gene

mRNA/cDNA for MIR4460 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4460 Gene

No ASD Table

Relevant External Links for MIR4460 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4460 Gene

mRNA expression in normal human tissues for MIR4460 Gene

genes like me logo Genes that share expressions with MIR4460: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR4460 Gene

Orthologs for MIR4460 Gene

Evolution for MIR4460 Gene

Gene Tree for MIR4460 (if available)
Gene Tree for MIR4460 (if available)

No data available for Orthologs for MIR4460 Gene

Paralogs for MIR4460 Gene

No data available for Paralogs for MIR4460 Gene

Variants for MIR4460 Gene

Sequence variations from dbSNP and Humsavar for MIR4460 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs7443230 -- 129,397,155(+) TGCCT(C/T)TCTGT upstream-variant-2KB
rs9632471 -- 129,398,302(+) CCCAG(C/G)CTGTC upstream-variant-2KB
rs12187568 -- 129,398,315(+) TCCCC(C/G)CTCAA upstream-variant-2KB
rs12233977 -- 129,398,277(+) CAGTG(A/G)ATGCA upstream-variant-2KB
rs12656592 -- 129,397,879(+) TAAGA(C/T)ACTTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4460 Gene

Variant ID Type Subtype PubMed ID
nsv882852 CNV Gain 21882294
dgv1849e1 CNV Complex 17122850
dgv1850e1 CNV Complex 17122850
dgv206e55 CNV Loss 17911159
nsv10749 CNV Loss 18304495
esv2659317 CNV Deletion 23128226
nsv818383 CNV Loss 17921354
esv2752060 CNV Gain 17911159
nsv882857 CNV Loss 21882294

Relevant External Links for MIR4460 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR4460 Gene

Disorders for MIR4460 Gene

No disorders were found for MIR4460 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR4460 Gene

Publications for MIR4460 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3

Products for MIR4460 Gene

Sources for MIR4460 Gene

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