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MIR4448 Gene(RNA Gene)

MicroRNA 4448

GCID:
GC03P183886
GIFtS:
12
Genes Participants
UDN Logo

Aliases for MIR4448 Gene

Subcategory (RNA class) for MIR4448 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4448 Gene

  • MicroRNA 4448 2 3 5
  • Hsa-Mir-4448 3

External Ids for MIR4448 Gene

Previous GeneCards Identifiers for MIR4448 Gene

  • GC03U901791
  • GC03P183609

Summaries for MIR4448 Gene

Entrez Gene Summary for MIR4448 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4448 Gene

MIR4448 (MicroRNA 4448) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4448 Gene

Genomics for MIR4448 Gene

Products:

  1. Regulatory Element

Regulatory Elements for MIR4448 Gene

Enhancers for MIR4448 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR4448 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4448 Gene

Chromosome:
3
Start:
183,886,800 bp from pter
End:
183,886,885 bp from pter
Size:
86 bases
Orientation:
Plus strand

Genomic View for MIR4448 Gene

Genes around MIR4448 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4448 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4448 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR4448 Gene

Proteins for MIR4448 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR4448 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4448 Gene

Domains & Families for MIR4448 Gene

Gene Families for MIR4448 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4448: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4448 Gene

Function for MIR4448 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4448 Gene

Localization for MIR4448 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4448 Gene

Pathways & Interactions for MIR4448 Gene

SuperPathways for MIR4448 Gene

PathCards logoMore details on SuperPathways for MIR4448
No Data Available

Interacting Proteins for MIR4448 Gene

Gene Ontology (GO) - Biological Process for MIR4448 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4448 Gene

Drugs & Compounds for MIR4448 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR4448 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for MIR4448 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4448 Gene

No ASD Table

Relevant External Links for MIR4448 Gene

GeneLoc Exon Structure for
MIR4448
ECgene alternative splicing isoforms for
MIR4448

Expression for MIR4448 Gene

Products:

  1. Primer

mRNA expression in normal human tissues for MIR4448 Gene

mRNA expression in normal human tissues for MIR4448 Gene
mRNA expression by BioGPS for MIR4448 GenemRNA expression by GTEx for MIR4448 Gene
genes like me logo Genes that share expression patterns with MIR4448: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR4448 Gene

Orthologs for MIR4448 Gene

Evolution for MIR4448 Gene

ENSEMBL:
Gene Tree for MIR4448 (if available)
TreeFam:
Gene Tree for MIR4448 (if available)

No data available for Orthologs for MIR4448 Gene

Paralogs for MIR4448 Gene

No data available for Paralogs for MIR4448 Gene

Variants for MIR4448 Gene

Sequence variations from dbSNP and Humsavar for MIR4448 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs4420923 -- 183,887,013(+) gtgga(G/T)ggcct downstream-variant-500B
rs34548593 -- 183,887,381(+) CTACC(A/G)GTCTC downstream-variant-500B
rs11926967 -- 183,887,218(+) ctcct(C/T)tctct downstream-variant-500B
rs11926985 -- 183,887,061(+) taacc(A/G)tctcc downstream-variant-500B
rs1829515 -- 183,886,935(-) tgaca(C/T)gctac downstream-variant-500B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for MIR4448 Gene

Disorders for MIR4448 Gene

No disorders were found for MIR4448 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for MIR4448 Gene

Publications for MIR4448 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 67
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR4448 Gene

Sources for MIR4448 Gene

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