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Aliases for MIR4445 Gene

Subcategory (RNA class) for MIR4445 Gene


Quality Score for this RNA gene is


Aliases for MIR4445 Gene

  • MicroRNA 4445 2 3 5
  • Hsa-Mir-4445 3

External Ids for MIR4445 Gene

Previous GeneCards Identifiers for MIR4445 Gene

  • GC03U901788
  • GC03P109324

Summaries for MIR4445 Gene

Entrez Gene Summary for MIR4445 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4445 Gene

MIR4445 (MicroRNA 4445) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4445 Gene

Genomics for MIR4445 Gene

Genomic Location for MIR4445 Gene

109,602,828 bp from pter
109,602,897 bp from pter
70 bases
Plus strand

Genomic View for MIR4445 Gene

Genes around MIR4445 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4445 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4445 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4445 Gene

No data available for Regulatory Elements for MIR4445 Gene

Proteins for MIR4445 Gene

Post-translational modifications for MIR4445 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4445 Gene

Domains & Families for MIR4445 Gene

Gene Families for MIR4445 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4445: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4445 Gene

Function for MIR4445 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4445 Gene

Localization for MIR4445 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4445 Gene

Pathways & Interactions for MIR4445 Gene

SuperPathways for MIR4445 Gene

No Data Available

Interacting Proteins for MIR4445 Gene

Gene Ontology (GO) - Biological Process for MIR4445 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4445 Gene

Transcripts for MIR4445 Gene

mRNA/cDNA for MIR4445 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4445 Gene

No ASD Table

Relevant External Links for MIR4445 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4445 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4445 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4445 Gene

Orthologs for MIR4445 Gene

Evolution for MIR4445 Gene

Gene Tree for MIR4445 (if available)
Gene Tree for MIR4445 (if available)

No data available for Orthologs for MIR4445 Gene

Paralogs for MIR4445 Gene

No data available for Paralogs for MIR4445 Gene

Variants for MIR4445 Gene

Sequence variations from dbSNP and Humsavar for MIR4445 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs111670681 -- 109,601,157(+) TTTCA(-/T)TTTTT upstream-variant-2KB
rs113651668 -- 109,602,744(+) CAAAA(A/G)CAAAT upstream-variant-2KB
rs114212353 -- 109,602,946(+) ACATC(C/T)GACAA downstream-variant-500B
rs12629205 -- 109,601,691(+) ttttt(C/T)tgttt upstream-variant-2KB
rs139254201 -- 109,602,737(+) AAGAA(C/T)CCAAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4445 Gene

Variant ID Type Subtype PubMed ID
nsv591268 CNV loss 21841781
nsv470827 CNV loss 18288195
nsv460814 CNV loss 19166990

Relevant External Links for MIR4445 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4445 Gene

Disorders for MIR4445 Gene

Relevant External Links for MIR4445

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4445 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4445 Gene

Publications for MIR4445 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4445 Gene

Sources for MIR4445 Gene

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