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Aliases for MIR4444-2 Gene

Subcategory (RNA class) for MIR4444-2 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4444-2 Gene

  • MicroRNA 4444-2 2 3 5
  • Hsa-Mir-4444-2 3

External Ids for MIR4444-2 Gene

Previous GeneCards Identifiers for MIR4444-2 Gene

  • GC03U901823
  • GC02P178079

Summaries for MIR4444-2 Gene

Entrez Gene Summary for MIR4444-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4444-2 Gene

MIR4444-2 (MicroRNA 4444-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4444-2 Gene

Genomics for MIR4444-2 Gene

Regulatory Elements for MIR4444-2 Gene

Enhancers for MIR4444-2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR4444-2 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4444-2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MIR4444-2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4444-2 Gene

Chromosome:
3
Start:
75,214,476 bp from pter
End:
75,214,549 bp from pter
Size:
74 bases
Orientation:
Plus strand

Genomic View for MIR4444-2 Gene

Genes around MIR4444-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4444-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4444-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4444-2 Gene

Proteins for MIR4444-2 Gene

Post-translational modifications for MIR4444-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4444-2 Gene

Domains & Families for MIR4444-2 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4444-2 Gene

Function for MIR4444-2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4444-2 Gene

Localization for MIR4444-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4444-2 Gene

Pathways & Interactions for MIR4444-2 Gene

SuperPathways for MIR4444-2 Gene

No Data Available

Interacting Proteins for MIR4444-2 Gene

Gene Ontology (GO) - Biological Process for MIR4444-2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4444-2 Gene

Drugs & Compounds for MIR4444-2 Gene

No Compound Related Data Available

Transcripts for MIR4444-2 Gene

mRNA/cDNA for MIR4444-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4444-2 Gene

No ASD Table

Relevant External Links for MIR4444-2 Gene

GeneLoc Exon Structure for
MIR4444-2
ECgene alternative splicing isoforms for
MIR4444-2

Expression for MIR4444-2 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR4444-2 Gene

Orthologs for MIR4444-2 Gene

Evolution for MIR4444-2 Gene

ENSEMBL:
Gene Tree for MIR4444-2 (if available)
TreeFam:
Gene Tree for MIR4444-2 (if available)

No data available for Orthologs for MIR4444-2 Gene

Paralogs for MIR4444-2 Gene

No data available for Paralogs for MIR4444-2 Gene

Variants for MIR4444-2 Gene

Sequence variations from dbSNP and Humsavar for MIR4444-2 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs7635785 -- 75,214,571(+) CGCCC(A/G)GTCGC downstream-variant-500B
rs7637795 -- 75,214,213(+) GAACA(G/T)TTGGG upstream-variant-2KB
rs7637796 -- 75,214,214(+) AACAT(C/T)TGGGA upstream-variant-2KB
rs55902535 -- 75,214,849(+) AAGGT(C/T)GATGG downstream-variant-500B
rs143269893 -- 75,213,612(+) AAAAT(C/T)GAGCT upstream-variant-2KB

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for MIR4444-2 Gene

Disorders for MIR4444-2 Gene

Relevant External Links for MIR4444-2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4444-2

No disorders were found for MIR4444-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4444-2 Gene

Publications for MIR4444-2 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 67
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR4444-2 Gene

Sources for MIR4444-2 Gene

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