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Aliases for MIR4444-1 Gene

Subcategory (RNA class) for MIR4444-1 Gene


Quality Score for this RNA gene is


Aliases for MIR4444-1 Gene

  • MicroRNA 4444-1 2 3 5
  • MicroRNA 4444 2 3
  • Hsa-Mir-4444-1 3
  • Hsa-Mir-4444 3
  • MIR4444 3

External Ids for MIR4444-1 Gene

Previous HGNC Symbols for MIR4444-1 Gene

  • MIR4444

Previous GeneCards Identifiers for MIR4444-1 Gene

  • GC02U902482
  • GC02P178078
  • GC02P178080

Summaries for MIR4444-1 Gene

Entrez Gene Summary for MIR4444-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4444-1 Gene

MIR4444-1 (MicroRNA 4444-1) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are mRNA Splicing - Major Pathway and Gene Expression.

Additional gene information for MIR4444-1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4444-1 Gene

Genomics for MIR4444-1 Gene

Regulatory Elements for MIR4444-1 Gene

Enhancers for MIR4444-1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02H177210 1.4 ENCODE dbSUPER 0.7 +0.5 507 5.4 HDGF PKNOX1 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 HNRNPA3 DNAJC19P5 RBM45 NFE2L2 LOC100130691 LOC105373754 MIR4444-1 LOC105373759
GH02H177215 0.6 dbSUPER 0.7 +3.7 3669 0.8 PAF1 POLR2A HLF CEBPB BACH1 SUPT5H MIR4444-1 LOC105373759
GH02H177222 0.6 dbSUPER 0.4 +9.9 9942 0.4 PAF1 SMAD5 ZBED1 CHD7 SSRP1 POLR2A RFXANK MYNN HOMEZ SUPT5H ENSG00000222043 NFE2L2 LOC100130691 LOC105373754 LOC105373759 MIR4444-1
GH02H177218 0.4 dbSUPER 0.4 +6.0 6049 1.2 POLR2A ENSG00000222043 NFE2L2 MIR4444-1 LOC105373759
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4444-1 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4444-1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Locations for MIR4444-1 Gene

Genomic Locations for MIR4444-1 Gene
74 bases
Plus strand

Genomic View for MIR4444-1 Gene

Genes around MIR4444-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4444-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4444-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4444-1 Gene

Proteins for MIR4444-1 Gene

Post-translational modifications for MIR4444-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4444-1 Gene

Domains & Families for MIR4444-1 Gene

Gene Families for MIR4444-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4444-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4444-1 Gene

Function for MIR4444-1 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4444-1 Gene

Localization for MIR4444-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4444-1 Gene

Pathways & Interactions for MIR4444-1 Gene

genes like me logo Genes that share pathways with MIR4444-1: view

Pathways by source for MIR4444-1 Gene

Interacting Proteins for MIR4444-1 Gene

Gene Ontology (GO) - Biological Process for MIR4444-1 Gene


No data available for SIGNOR curated interactions for MIR4444-1 Gene

Drugs & Compounds for MIR4444-1 Gene

No Compound Related Data Available

Transcripts for MIR4444-1 Gene

mRNA/cDNA for MIR4444-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4444-1 Gene

No ASD Table

Relevant External Links for MIR4444-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4444-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4444-1 Gene

genes like me logo Genes that share expression patterns with MIR4444-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4444-1 Gene

Orthologs for MIR4444-1 Gene

Evolution for MIR4444-1 Gene

Gene Tree for MIR4444-1 (if available)
Gene Tree for MIR4444-1 (if available)

No data available for Orthologs for MIR4444-1 Gene

Paralogs for MIR4444-1 Gene

No data available for Paralogs for MIR4444-1 Gene

Variants for MIR4444-1 Gene

Sequence variations from dbSNP and Humsavar for MIR4444-1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1001236041 -- 177,213,277(+) GATCC(A/G)CCGCC intron-variant, downstream-variant-500B, upstream-variant-2KB, reference, missense
rs1001603857 -- 177,213,162(+) AGGGC(A/G)GCATG intron-variant, downstream-variant-500B, upstream-variant-2KB, reference, missense
rs1002254146 -- 177,212,394(+) AACTA(A/G)AGGCC intron-variant, upstream-variant-2KB
rs1003322689 -- 177,212,585(+) GGCGC(A/G)CGCGC intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1003665974 -- 177,213,279(+) TCCGC(C/T)GCCGC intron-variant, downstream-variant-500B, upstream-variant-2KB, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for MIR4444-1 Gene

Variant ID Type Subtype PubMed ID
nsv963330 CNV duplication 23825009
nsv834736 CNV gain 17160897
nsv834465 CNV loss 17160897
nsv590641 CNV gain 21841781
nsv460704 CNV gain 19166990
nsv1002218 CNV loss 25217958
esv3893725 CNV gain 25118596
esv2422315 CNV deletion 17116639
esv2422240 CNV deletion 17116639

Relevant External Links for MIR4444-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4444-1 Gene

Disorders for MIR4444-1 Gene

Relevant External Links for MIR4444-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4444-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4444-1 Gene

Publications for MIR4444-1 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4444-1 Gene

Sources for MIR4444-1 Gene

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