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Aliases for MIR4443 Gene

Subcategory (RNA class) for MIR4443 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4443 Gene

  • MicroRNA 4443 2 3
  • Hsa-Mir-4443 3

External Ids for MIR4443 Gene

Summaries for MIR4443 Gene

Entrez Gene Summary for MIR4443 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4443 Gene

MIR4443 (MicroRNA 4443) is an RNA Gene, and belongs to the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4443 Gene

Genomics for MIR4443 Gene

Genomic Location for MIR4443 Gene

Start:
48,196,564 bp from pter
End:
48,196,616 bp from pter
Size:
53 bases
Orientation:
Plus strand

Genomic View for MIR4443 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4443 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4443 Gene

No data available for Regulatory Elements for MIR4443 Gene

Proteins for MIR4443 Gene

Post-translational modifications for MIR4443 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4443 Gene

Domains for MIR4443 Gene

Gene Families for MIR4443 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4443: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4443 Gene

Function for MIR4443 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR4443 Gene

Localization for MIR4443 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4443 Gene

Pathways for MIR4443 Gene

SuperPathways for MIR4443 Gene

No Data Available

Interacting Proteins for MIR4443 Gene

Gene Ontology (GO) - Biological Process for MIR4443 Gene

None

No data available for Pathways by source for MIR4443 Gene

Transcripts for MIR4443 Gene

mRNA/cDNA for MIR4443 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4443 Gene

No ASD Table

Relevant External Links for MIR4443 Gene

GeneLoc Exon Structure for
MIR4443
ECgene alternative splicing isoforms for
MIR4443

Expression for MIR4443 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR4443 Gene

Orthologs for MIR4443 Gene

Evolution for MIR4443 Gene

ENSEMBL:
Gene Tree for MIR4443 (if available)
TreeFam:
Gene Tree for MIR4443 (if available)

No data available for Orthologs for MIR4443 Gene

Paralogs for MIR4443 Gene

No data available for Paralogs for MIR4443 Gene

Variants for MIR4443 Gene

Sequence variations from dbSNP and Humsavar for MIR4443 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs2885337 -- 48,195,086(-) cctcc(A/C)taagt upstream-variant-2KB
rs6796490 -- 48,195,614(+) CGAGG(G/T)GTTGC upstream-variant-2KB
rs7647817 -- 48,195,017(+) TCTCA(A/G)TTGTA upstream-variant-2KB
rs9861298 -- 48,196,649(+) AGGCC(C/G)ATTCC downstream-variant-500B
rs11299572 -- 48,195,742(+) ACTGC(-/T)TTTTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4443 Gene

Variant ID Type Subtype PubMed ID
nsv834682 CNV Gain 17160897

Relevant External Links for MIR4443 Gene

HapMap Linkage Disequilibrium report
MIR4443

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR4443 Gene

Disorders for MIR4443 Gene

No disorders were found for MIR4443 Gene.

No data available for UniProtKB/Swiss-Prot for MIR4443 Gene

Publications for MIR4443 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3

Products for MIR4443 Gene

Sources for MIR4443 Gene

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