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Aliases for MIR4443 Gene

Subcategory (RNA class) for MIR4443 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4443 Gene

  • MicroRNA 4443 2 3 5
  • Hsa-Mir-4443 3
  • Mir-4443 3

External Ids for MIR4443 Gene

Previous GeneCards Identifiers for MIR4443 Gene

  • GC03U901809
  • GC03P048242

Summaries for MIR4443 Gene

Entrez Gene Summary for MIR4443 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4443 Gene

MIR4443 (MicroRNA 4443) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4443 Gene

Genomics for MIR4443 Gene

Regulatory Elements for MIR4443 Gene

Enhancers for MIR4443 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03G048194 1.1 Ensembl ENCODE 0.7 -1.9 -1864 0.6 CTCF ESRRA MXI1 TAL1 MAX ZNF384 YBX1 EBF1 THRB RAD21 MIR4443 CDC25A
GH03G048191 0.9 ENCODE 0.4 -5.4 -5399 0.2 ARID4B DMAP1 ZNF2 SP3 MIER2 REST TBX21 ZNF518A KAT8 NBN CDC25A MIR4443
GH03G048190 0.4 ENCODE 0.4 -6.1 -6090 0.6 BHLHE40 KDM1A QRICH1 CDC25A MIR4443
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4443 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4443 Gene

Chromosome:
3
Start:
48,196,564 bp from pter
End:
48,196,616 bp from pter
Size:
53 bases
Orientation:
Plus strand

Genomic View for MIR4443 Gene

Genes around MIR4443 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4443 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4443 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4443 Gene

Proteins for MIR4443 Gene

Post-translational modifications for MIR4443 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4443 Gene

Domains & Families for MIR4443 Gene

Gene Families for MIR4443 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4443: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4443 Gene

Function for MIR4443 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4443 Gene

Localization for MIR4443 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4443 Gene

Pathways & Interactions for MIR4443 Gene

SuperPathways for MIR4443 Gene

No Data Available

Interacting Proteins for MIR4443 Gene

Gene Ontology (GO) - Biological Process for MIR4443 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4443 Gene

Drugs & Compounds for MIR4443 Gene

No Compound Related Data Available

Transcripts for MIR4443 Gene

mRNA/cDNA for MIR4443 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4443 Gene

No ASD Table

Relevant External Links for MIR4443 Gene

GeneLoc Exon Structure for
MIR4443
ECgene alternative splicing isoforms for
MIR4443

Expression for MIR4443 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4443 Gene:

MIR4443
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4443 Gene

Orthologs for MIR4443 Gene

Evolution for MIR4443 Gene

ENSEMBL:
Gene Tree for MIR4443 (if available)
TreeFam:
Gene Tree for MIR4443 (if available)

No data available for Orthologs for MIR4443 Gene

Paralogs for MIR4443 Gene

No data available for Paralogs for MIR4443 Gene

Variants for MIR4443 Gene

Sequence variations from dbSNP and Humsavar for MIR4443 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1002367040 -- 48,196,872(+) CATGA(A/G)GAACC downstream-variant-500B
rs1003110764 -- 48,195,383(+) TCCCA(C/T)ACAGA upstream-variant-2KB
rs1003121414 -- 48,195,893(+) CCCGC(C/T)ACCAC upstream-variant-2KB
rs1003240250 -- 48,197,100(+) CAGCG(A/G)GGTAG downstream-variant-500B
rs1003723443 -- 48,196,887(+) TCACA(A/G)AGAAT downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4443 Gene

Variant ID Type Subtype PubMed ID
nsv1012024 CNV gain 25217958
nsv834682 CNV gain 17160897

Relevant External Links for MIR4443 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4443

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4443 Gene

Disorders for MIR4443 Gene

Relevant External Links for MIR4443

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4443

No disorders were found for MIR4443 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4443 Gene

Publications for MIR4443 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4443 Gene

Sources for MIR4443 Gene

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