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Aliases for MIR4440 Gene

Subcategory (RNA class) for MIR4440 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4440 Gene

  • MicroRNA 4440 2 3 5
  • Hsa-Mir-4440 3
  • Mir-4440 3

External Ids for MIR4440 Gene

Previous GeneCards Identifiers for MIR4440 Gene

  • GC02U902444
  • GC02M239992
  • GC02M239075
  • GC02M239083
  • GC02M239096
  • GC02M239099
  • GC02M239101

Summaries for MIR4440 Gene

Entrez Gene Summary for MIR4440 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4440 Gene

MIR4440 (MicroRNA 4440) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4440 Gene

Genomics for MIR4440 Gene

Regulatory Elements for MIR4440 Gene

Enhancers for MIR4440 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02G239083 0.7 dbSUPER 0.4 -16.0 -16008 2.0 SUZ12 TAL1 E2F7 TCF12 ZFHX2 GATA2 NCOR1 ZSCAN29 TRIM24 BCLAF1 HDAC4 MIR4441 MIR4440
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4440 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4440 Gene

Chromosome:
2
Start:
239,068,817 bp from pter
End:
239,068,914 bp from pter
Size:
98 bases
Orientation:
Minus strand

Genomic View for MIR4440 Gene

Genes around MIR4440 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4440 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4440 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4440 Gene

Proteins for MIR4440 Gene

Post-translational modifications for MIR4440 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4440 Gene

Domains & Families for MIR4440 Gene

Gene Families for MIR4440 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4440: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4440 Gene

Function for MIR4440 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4440 Gene

Localization for MIR4440 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4440 Gene

Pathways & Interactions for MIR4440 Gene

SuperPathways for MIR4440 Gene

No Data Available

Interacting Proteins for MIR4440 Gene

Gene Ontology (GO) - Biological Process for MIR4440 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4440 Gene

Drugs & Compounds for MIR4440 Gene

No Compound Related Data Available

Transcripts for MIR4440 Gene

mRNA/cDNA for MIR4440 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4440 Gene

No ASD Table

Relevant External Links for MIR4440 Gene

GeneLoc Exon Structure for
MIR4440
ECgene alternative splicing isoforms for
MIR4440

Expression for MIR4440 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4440 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4440 Gene:

MIR4440
genes like me logo Genes that share expression patterns with MIR4440: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4440 Gene

Orthologs for MIR4440 Gene

Evolution for MIR4440 Gene

ENSEMBL:
Gene Tree for MIR4440 (if available)
TreeFam:
Gene Tree for MIR4440 (if available)

No data available for Orthologs for MIR4440 Gene

Paralogs for MIR4440 Gene

No data available for Paralogs for MIR4440 Gene

Variants for MIR4440 Gene

Sequence variations from dbSNP and Humsavar for MIR4440 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1001443813 -- 239,070,231(+) CACCA(A/G)CACAC intron-variant, upstream-variant-2KB
rs1002475343 -- 239,069,975(+) CCGTG(C/T)CCACC intron-variant, upstream-variant-2KB
rs1002527802 -- 239,070,346(+) TTCTT(C/T)AAATT intron-variant, upstream-variant-2KB
rs1002652408 -- 239,070,572(+) CACCA(C/T)TGACT intron-variant, upstream-variant-2KB
rs1004872069 -- 239,068,322(+) GCTCT(C/T)TGGGG intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4440 Gene

Variant ID Type Subtype PubMed ID
nsv508896 CNV insertion 20534489
nsv818118 CNV gain 17921354
nsv834578 CNV loss 17160897

Relevant External Links for MIR4440 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4440

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4440 Gene

Disorders for MIR4440 Gene

Relevant External Links for MIR4440

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4440

No disorders were found for MIR4440 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4440 Gene

Publications for MIR4440 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4440 Gene

Sources for MIR4440 Gene

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