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Aliases for MIR4438 Gene

Subcategory (RNA class) for MIR4438 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4438 Gene

  • MicroRNA 4438 2 3 5
  • Hsa-Mir-4438 3

External Ids for MIR4438 Gene

Previous GeneCards Identifiers for MIR4438 Gene

  • GC02U902424
  • GC02P214624

Summaries for MIR4438 Gene

Entrez Gene Summary for MIR4438 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4438 Gene

MIR4438 (MicroRNA 4438) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4438 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4438 Gene

Genomics for MIR4438 Gene

Regulatory Elements for MIR4438 Gene

Enhancers for MIR4438 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02H213722 0.5 ENCODE 0.3 -34.7 -34666 1 MAFF GATA3 ATF7 ATF2 MAFK MIR4438 GC02P213538
GH02H213687 0.4 ENCODE 0.2 -69.9 -69860 0 POU5F1 SPAG16 MIR4438 GC02P213538
GH02H213702 0.3 FANTOM5 0.2 -55.9 -55887 0 SPAG16 LOC100130451 MIR4438 GC02P213538
GH02H213664 0.2 ENCODE 0.2 -93.2 -93170 1 MIR4438 GC02P213538
GH02H213594 0.2 ENCODE 0.1 -163.3 -163328 0 GC02P213538 MIR4438
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4438 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4438 Gene

Chromosome:
2
Start:
213,758,067 bp from pter
End:
213,758,159 bp from pter
Size:
93 bases
Orientation:
Plus strand

Genomic View for MIR4438 Gene

Genes around MIR4438 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4438 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4438 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4438 Gene

Proteins for MIR4438 Gene

Post-translational modifications for MIR4438 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4438 Gene

Domains & Families for MIR4438 Gene

Gene Families for MIR4438 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4438: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4438 Gene

Function for MIR4438 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4438
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4438 Gene

Localization for MIR4438 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4438 Gene

Pathways & Interactions for MIR4438 Gene

SuperPathways for MIR4438 Gene

No Data Available

Interacting Proteins for MIR4438 Gene

Gene Ontology (GO) - Biological Process for MIR4438 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4438 Gene

Drugs & Compounds for MIR4438 Gene

No Compound Related Data Available

Transcripts for MIR4438 Gene

mRNA/cDNA for MIR4438 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4438
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4438 Gene

No ASD Table

Relevant External Links for MIR4438 Gene

GeneLoc Exon Structure for
MIR4438
ECgene alternative splicing isoforms for
MIR4438

Expression for MIR4438 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4438 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4438 Gene:

MIR4438
genes like me logo Genes that share expression patterns with MIR4438: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4438 Gene

Orthologs for MIR4438 Gene

Evolution for MIR4438 Gene

ENSEMBL:
Gene Tree for MIR4438 (if available)
TreeFam:
Gene Tree for MIR4438 (if available)

No data available for Orthologs for MIR4438 Gene

Paralogs for MIR4438 Gene

No data available for Paralogs for MIR4438 Gene

Variants for MIR4438 Gene

Sequence variations from dbSNP and Humsavar for MIR4438 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1002491089 -- 213,758,616(+) GTAAA(C/T)TTGAA intron-variant, downstream-variant-500B
rs1002824925 -- 213,757,022(+) ATAAA(C/T)GTATT intron-variant, upstream-variant-2KB
rs1002955737 -- 213,757,735(+) GCACA(A/T)GTTAC intron-variant, upstream-variant-2KB
rs1003160041 -- 213,758,121(+) CTTTG(G/T)CACAG intron-variant, nc-transcript-variant
rs1005528418 -- 213,756,971(+) TGGAA(C/T)GTAAA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4438 Gene

Variant ID Type Subtype PubMed ID
esv3893551 CNV loss 25118596
nsv1013630 CNV loss 25217958

Relevant External Links for MIR4438 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4438

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4438 Gene

Disorders for MIR4438 Gene

Relevant External Links for MIR4438

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4438

No disorders were found for MIR4438 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4438 Gene

Publications for MIR4438 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4438 Gene

Sources for MIR4438 Gene

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