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Aliases for MIR4436A Gene

Subcategory (RNA class) for MIR4436A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4436A Gene

  • MicroRNA 4436a 2 3 5
  • Hsa-Mir-4436a 3
  • Mir-4436a 3

External Ids for MIR4436A Gene

Previous GeneCards Identifiers for MIR4436A Gene

  • GC02U902435
  • GC02P089113

Summaries for MIR4436A Gene

Entrez Gene Summary for MIR4436A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4436A Gene

MIR4436A (MicroRNA 4436a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4436A Gene

Genomics for MIR4436A Gene

Genomic Location for MIR4436A Gene

Chromosome:
2
Start:
88,812,370 bp from pter
End:
88,812,454 bp from pter
Size:
85 bases
Orientation:
Plus strand

Genomic View for MIR4436A Gene

Genes around MIR4436A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4436A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4436A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4436A Gene

No data available for Regulatory Elements for MIR4436A Gene

Proteins for MIR4436A Gene

Post-translational modifications for MIR4436A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4436A Gene

Domains & Families for MIR4436A Gene

Gene Families for MIR4436A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4436A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4436A Gene

Function for MIR4436A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4436A Gene

Localization for MIR4436A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4436A Gene

Pathways & Interactions for MIR4436A Gene

SuperPathways for MIR4436A Gene

No Data Available

Interacting Proteins for MIR4436A Gene

Gene Ontology (GO) - Biological Process for MIR4436A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4436A Gene

Drugs & Compounds for MIR4436A Gene

No Compound Related Data Available

Transcripts for MIR4436A Gene

mRNA/cDNA for MIR4436A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4436A Gene

No ASD Table

Relevant External Links for MIR4436A Gene

GeneLoc Exon Structure for
MIR4436A
ECgene alternative splicing isoforms for
MIR4436A

Expression for MIR4436A Gene

mRNA expression in normal human tissues for MIR4436A Gene

genes like me logo Genes that share expression patterns with MIR4436A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR4436A Gene

Orthologs for MIR4436A Gene

Evolution for MIR4436A Gene

ENSEMBL:
Gene Tree for MIR4436A (if available)
TreeFam:
Gene Tree for MIR4436A (if available)

No data available for Orthologs for MIR4436A Gene

Paralogs for MIR4436A Gene

No data available for Paralogs for MIR4436A Gene

Variants for MIR4436A Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4436A Gene

Variant ID Type Subtype PubMed ID
dgv61n16 CNV Deletion 17901297
nsv470476 CNV Gain 18288195
nsv874582 CNV Gain 21882294
nsv834290 CNV Loss 17160897
nsv874583 CNV Gain 21882294
dgv4228n71 CNV Gain 21882294
nsv2824 CNV Loss 18451855
nsv7318 OTHER Inversion 18451855
nsv190 CNV Loss 15895083
nsv508153 CNV Loss 20534489

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Variation tolerance and Relevant External Links for MIR4436A Gene

Disorders for MIR4436A Gene

Relevant External Links for MIR4436A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4436A

No disorders were found for MIR4436A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4436A Gene

Publications for MIR4436A Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 67
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3
  3. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR4436A Gene

Sources for MIR4436A Gene

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