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Aliases for MIR4435-2HG Gene

Subcategory (RNA class) for MIR4435-2HG Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4435-2HG Gene

  • MIR4435-2 Host Gene 2 3 5
  • Long Intergenic Non-Protein Coding RNA 978 2 3
  • Adipogenesis Down-Regulated Transcript 2 2 3
  • MIR4435-1 Host Gene (Non-Protein Coding) 2 3
  • MIR4435-1 Host Gene 2
  • MIR4435-1HG 3
  • LINC00978 3
  • AK001796 3
  • AGD2 3

External Ids for MIR4435-2HG Gene

Previous HGNC Symbols for MIR4435-2HG Gene

  • MIR4435-1HG

Summaries for MIR4435-2HG Gene

GeneCards Summary for MIR4435-2HG Gene

MIR4435-2HG (MIR4435-2 Host Gene) is an RNA Gene, and is affiliated with the miRNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4435-2HG Gene

Genomics for MIR4435-2HG Gene

Regulatory Elements for MIR4435-2HG Gene

Enhancers for MIR4435-2HG Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F111493 1.5 FANTOM5 ENCODE 5.4 -0.7 -713 4.8 HDGF PKNOX1 MLX CREB3L1 ZFP64 ARID4B SIN3A DMAP1 FEZF1 YY1 LOC105373559 MIR4435-2HG MERTK BCL2L11 PIR35996
GH02F111622 1.5 FANTOM5 Ensembl ENCODE 5 -129.5 -129461 4.5 HDAC1 PKNOX1 CBX3 ATF1 TBL1XR1 RAD21 CHAMP1 GATA2 RCOR1 FOS MIR4435-2HG LOC105373559 RPL34P8
GH02F111658 1.6 FANTOM5 Ensembl ENCODE 4.3 -166.4 -166356 6.0 PKNOX1 ARID4B DMAP1 GATA2 CBX5 FOS NCOA1 REST ZNF592 SMARCA4 MIR4435-2HG RPL34P8 LOC105373559
GH02F111478 1 Ensembl ENCODE 6.5 +14.9 14915 3.6 CTCF SCRT1 KLF1 MAFG ZIC2 ZNF121 ZFP69B ZFHX2 ZNF692 GLIS1 MIR4435-2HG EEF1E1P1 LOC105373557 ENSG00000280878
GH02F111510 0.6 Ensembl 4.6 -15.9 -15887 1.6 CBX3 GLIS1 FEZF1 ZIC2 ZNF423 MIR4435-2HG LOC105373559 PIR35996
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4435-2HG on UCSC Golden Path with GeneCards custom track

Promoters for MIR4435-2HG Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000596631 1015 2201 ELF3 HDAC1 NFRKB ZNF76 ARID4B FEZF1 ZNF366 FOS REST ZEB2

Genomic Location for MIR4435-2HG Gene

Chromosome:
2
Start:
111,196,350 bp from pter
End:
111,495,115 bp from pter
Size:
298,766 bases
Orientation:
Minus strand

Genomic View for MIR4435-2HG Gene

Genes around MIR4435-2HG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4435-2HG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4435-2HG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4435-2HG Gene

Proteins for MIR4435-2HG Gene

Post-translational modifications for MIR4435-2HG Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4435-2HG Gene

Domains & Families for MIR4435-2HG Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4435-2HG Gene

Function for MIR4435-2HG Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4435-2HG Gene

Localization for MIR4435-2HG Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4435-2HG Gene

Pathways & Interactions for MIR4435-2HG Gene

SuperPathways for MIR4435-2HG Gene

No Data Available

Interacting Proteins for MIR4435-2HG Gene

Gene Ontology (GO) - Biological Process for MIR4435-2HG Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4435-2HG Gene

Transcripts for MIR4435-2HG Gene

mRNA/cDNA for MIR4435-2HG Gene

(20) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4435-2HG Gene

No ASD Table

Relevant External Links for MIR4435-2HG Gene

GeneLoc Exon Structure for
MIR4435-2HG
ECgene alternative splicing isoforms for
MIR4435-2HG

Expression for MIR4435-2HG Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4435-2HG Gene

Orthologs for MIR4435-2HG Gene

Evolution for MIR4435-2HG Gene

ENSEMBL:
Gene Tree for MIR4435-2HG (if available)
TreeFam:
Gene Tree for MIR4435-2HG (if available)

No data available for Orthologs for MIR4435-2HG Gene

Paralogs for MIR4435-2HG Gene

No data available for Paralogs for MIR4435-2HG Gene

Variants for MIR4435-2HG Gene

Sequence variations from dbSNP and Humsavar for MIR4435-2HG Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1004117 -- 111,441,600(+) GGAAC(A/G)TGGTT intron-variant
rs1004504 -- 111,442,889(-) TTCTC(A/G)TCTGC intron-variant
rs1009790 -- 111,319,273(-) CAGGC(A/G)GGGAA intron-variant
rs1009791 -- 111,319,216(-) GCAAA(C/G)GAAAC intron-variant
rs1009792 -- 111,318,973(-) actcc(A/G)tctct intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4435-2HG Gene

Variant ID Type Subtype PubMed ID
nsv998690 CNV gain 25217958
nsv961868 CNV duplication 23825009
nsv953797 CNV duplication 24416366
nsv834332 CNV gain+loss 17160897
nsv821628 CNV gain 15273396
nsv818077 CNV gain 17921354
nsv582700 CNV loss 21841781
nsv582699 CNV loss 21841781
nsv522475 CNV gain 19592680
nsv521956 CNV loss 19592680
nsv469744 CNV gain 16826518
nsv441774 CNV gain 18776908
nsv428402 CNV loss 18775914
nsv2878 CNV insertion 18451855
nsv1149522 OTHER inversion 26484159
nsv1147924 CNV duplication 26484159
nsv1077889 CNV duplication 25765185
nsv1076491 CNV duplication 25765185
nsv1014545 CNV gain 25217958
nsv10126 CNV gain+loss 18304495
nsv1001733 CNV gain+loss 25217958
esv3893082 CNV gain 25118596
esv3591987 CNV gain 21293372
esv3591986 CNV gain 21293372
esv3591985 CNV loss 21293372
esv3584012 CNV loss 25503493
esv3347759 CNV duplication 20981092
esv32858 CNV loss 17666407
esv2759083 CNV gain+loss 17122850
esv2720518 CNV deletion 23290073
esv26325 CNV gain+loss 19812545
dgv731e214 CNV gain 21293372
dgv4052n100 CNV gain 25217958
dgv4051n100 CNV gain 25217958
dgv4050n100 CNV gain 25217958
dgv4049n100 CNV gain 25217958
dgv4047n100 CNV loss 25217958
dgv1995n106 CNV duplication 24896259

Relevant External Links for MIR4435-2HG Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4435-2HG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4435-2HG Gene

Disorders for MIR4435-2HG Gene

Relevant External Links for MIR4435-2HG

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4435-2HG

No disorders were found for MIR4435-2HG Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4435-2HG Gene

Publications for MIR4435-2HG Gene

  1. A novel long noncoding RNA AK001796 acts as an oncogene and is involved in cell growth inhibition by resveratrol in lung cancer. (PMID: 25888808) Yang Q. … Jiang Y. (Toxicol. Appl. Pharmacol. 2015) 2 3 64
  2. Transcripts of unknown function in multiple-signaling pathways involved in human stem cell differentiation. (PMID: 19531736) Kikuchi K. … Aizawa Y. (Nucleic Acids Res. 2009) 2 3 64
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  4. Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population. (PMID: 23042114) Hirota T. … Tamari M. (Nat. Genet. 2012) 3 64
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64

Products for MIR4435-2HG Gene

Sources for MIR4435-2HG Gene

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